Uzion (20/1680mg) 10 Sachets

Omeprazole 20mg and Sodium Bicarbonate work synergistically to provide rapid relief from gastric acidity. Omeprazole belongs to the proton pump inhibitor (PPI) class of drugs and acts by specifically inhibiting the hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) enzyme system, also known as the gastric proton pump, which is located on the secretory surface of the gastric parietal cells. By inhibiting this pump, Omeprazole suppresses gastric acid secretion, thereby increasing gastric pH. Sodium Bicarbonate, on the other hand, is a buffering agent that works by neutralizing gastric acid, providing immediate relief from acidity. The combination of these two mechanisms ensures effective control of gastric acidity, making it useful in the treatment of various acid-related disorders.

Proton pump inhibitor.

Oral

The following are the uses of Omeprazole 20mg, Sodium Bicarbonate Sachet:

• Used for treating acid reflux and heartburn
• Used to reduce stomach acid and relieve symptoms of gastroesophageal reflux disease (GERD)
• Used for managing symptoms of stomach ulcers
• Used to aid in the healing of erosive esophagitis
• Used for treating conditions where the stomach produces too much acid
• Used to relieve acid-related pain and discomfort
• Used as a short-term treatment for acid reflux and indigestion

In the case of an overdose of Omeprazole 20mg and Sodium Bicarbonate Sachet, individuals may experience an array of symptoms. These can include gastrointestinal issues such as nausea, vomiting, and abdominal pain. Additionally, rapid heart rate, confusion, and dizziness may occur. Prompt medical intervention is necessary to manage these symptoms effectively and prevent potential complications arising from excessive ingestion of these medications.

In the case of a missed dose of Omeprazole 20mg, it is recommended to take the missed dose as soon as you remember, but if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. For Sodium Bicarbonate Sachet, if you miss a dose, take it as soon as you remember, however, if it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one.

To take Omeprazole 20mg and Sodium Bicarbonate Sachet, empty the contents of the sachet into a glass of water, stir well until dissolved, and drink the entire mixture immediately, preferably in the morning, 30 minutes before breakfast, as directed by your healthcare professional.

Here are the conditions or situations when Omeprazole 20mg and Sodium Bicarbonate Sachet should not be taken:

• Do not take if you are allergic to Omeprazole, Sodium Bicarbonate, or any other proton pump inhibitors (PPIs).
• Contraindicated in patients with a history of severe kidney disease.
• Avoid using if you have low magnesium levels or conditions that cause low magnesium levels.
• Do not take if you have an allergy to aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs).
• Not recommended for individuals with a history of stomach surgery or a recent history of gastrointestinal (GI) bleeding.
• Should not be used if you have a rare condition called Zollinger-Ellison syndrome.
• Avoid using if you have a genetic condition causing poor liver function.
• Contraindicated in patients with a history of severe liver impairment.

The side effects of Omeprazole 20mg and Sodium Bicarbonate Sachet may include:

• Headache
• Nausea and vomiting
• Diarrhea
• Abdominal pain or discomfort
• Flatulence (excessive gas)
• Dizziness
• Skin rash or itching
• Joint pain

Following are the precautions and warnings for Omeprazole 20mg and Sodium Bicarbonate Sachet:

• This medication should not be taken by individuals with a known allergy to Omeprazole, Sodium Bicarbonate, or any other ingredients in the sachet.
• Long-term use of Omeprazole may lead to vitamin B12 deficiency, so regular monitoring is necessary, especially in patients with reduced vitamin B12 absorption.
• Patients with liver problems should exercise caution, as Omeprazole is metabolized in the liver and may require dosage adjustments.
• Those with osteoporosis or at risk of osteoporosis should be monitored, as long-term use of high-dose Omeprazole can slightly increase the risk of bone fractures.
• If you are taking other medications, especially those that require stomach acidity for absorption, consult your doctor as Omeprazole can reduce the absorption of certain drugs.
• Do not take this medication if you are also taking medicines that contain rilpivirine (used to treat HIV) or atazanavir (used to treat HIV and hepatitis B).
• Pregnant and breastfeeding women should consult their healthcare provider before taking this medication.
• If you have severe kidney problems, consult your doctor before using Sodium Bicarbonate.

Following are the drug interactions for Omeprazole 20mg and Sodium Bicarbonate Sachet:

• Omeprazole may decrease the absorption of drugs like ketoconazole, atazanavir, and digoxin, requiring monitoring and potential dose adjustments.
• It can reduce the effectiveness of clopidogrel, an antiplatelet medication, potentially increasing the risk of cardiovascular events.
• Sodium Bicarbonate can decrease the stomach's acidity, affecting the absorption of certain medications like iron supplements and tetracycline antibiotics.
• It may interact with lithium, potentially leading to increased lithium levels and toxicity.
• Concomitant use with diazepam or phenytoin can affect their metabolism, requiring dosage adjustments.
• Antacids containing sodium bicarbonate may reduce the absorption of fluoroquinolone antibiotics, such as ciprofloxacin.
• Omeprazole can prolong the elimination of diazepam and other benzodiazepines, potentially leading to increased sedation and respiratory depression.

Following are the food interactions for Omeprazole 20mg and Sodium Bicarbonate Sachet:

• Avoid excessive consumption of acidic foods like citrus fruits, tomatoes, and vinegar-based dressings, as they can irritate the stomach and reduce the effectiveness of Omeprazole.
• Alcohol should be consumed in moderation as it can increase acid production and potentially reduce the medication's efficacy.
• Avoid high-sodium foods as Sodium Bicarbonate can already increase sodium levels in the body.
• Avoid carbonated beverages as they can cause belching and potentially reduce the absorption of Omeprazole.
• Caffeine intake should be limited as it can stimulate acid secretion and potentially counteract the effects of both medications.
• Avoid spicy foods, as they can irritate the stomach lining and exacerbate symptoms, reducing the effectiveness of the treatment.
• Consuming a diet rich in fruits, vegetables, and whole grains can aid in digestion and support the medications' effectiveness.
• Ensure adequate hydration by drinking enough water to maintain a healthy digestive system.

Omeprazole 20mg and Sodium Bicarbonate Sachet should be stored in a cool, dry place, preferably at room temperature, ensuring protection from light and moisture. Keep the medication in its original packaging, tightly sealed, to maintain its integrity and prevent exposure to air. Avoid storing it in the bathroom cabinet or near heat-emitting appliances to prevent degradation. Always check the expiration date before use and dispose of any unused or expired medication responsibly. Do not dispose of it in wastewater or household garbage; instead, follow local guidelines or consult a pharmacist for safe disposal methods. Keep the medication away from children to prevent accidental consumption.

Following are the quick tips for Omeprazole 20mg and Sodium Bicarbonate Sachet:

• Take the medication as directed by your doctor, typically once daily in the morning.
• Swallow the Omeprazole capsule whole with a glass of water; do not crush or chew.
• Mix the contents of the Sodium Bicarbonate Sachet with a glass of water and drink it 30 minutes before taking Omeprazole.
• Avoid taking this medication with other medicines; maintain a gap of at least 2 hours.
• Do not consume alcohol while taking this medication as it may reduce its effectiveness.
• Store Omeprazole at room temperature, away from moisture and heat.
• Ensure you complete the full course of treatment as prescribed by your doctor.