VANEKA CREAM 15ML

Apityzer Cream primarily works through its active ingredient, apixaban, which is an anticoagulant medication. The mechanism of action involves inhibiting the activity of Factor Xa, a key enzyme in the coagulation cascade. By blocking Factor Xa, Apityzer Cream interrupts the common pathway of both intrinsic and extrinsic coagulation pathways, thereby preventing the formation of thrombin and subsequently inhibiting the formation of blood clots. This action helps to prevent the development of deep vein thrombosis (DVT) and reduces the risk of pulmonary embolism (PE) by hindering the clotting process in the veins.

Aqua (water), Cocoglycerides, Ethylhexyl Palmitate, Prunus Amygdalus Dulcis Oil (Sweet Almond Oil), Glycerin, Dimethicone, Glycine Soja Extract (Glycine Soja Extract), Mannitol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Polysorbate-20, Tocopherol, Phenoxyethanol, Ascorbyl Palmitate, Sodium Hydroxide, Methylparaben, Parfum (Fragrance), Ethylparaben, Tertrasodium Edta, Lecithin, Citric Acid, Citronellol, Eugenol, Geraniol, Linalool, Hydroxycitronellal.

Corticosteroid.

Cream

The following are the uses of Apityzer Cream:

• Used for treating acne and reducing inflammation caused by skin conditions.
• Used for soothing skin irritation and relieving itching.
• Used for moisturizing dry skin and improving overall skin texture.
• Used for fading dark spots and promoting an even skin tone.
• Used for healing minor cuts, burns, and abrasions.
• Used for reducing the appearance of fine lines and wrinkles.
• Used for providing relief from sunburn and calming sun-damaged skin.
• Used for managing skin conditions like eczema and psoriasis, reducing redness and discomfort.

In the case of an overdose of Apityzer Cream, it is important to act promptly. If the cream is accidentally ingested, immediately rinse the mouth with water to minimize absorption. Seek medical advice by contacting a healthcare professional or a poison control center for guidance. They will provide specific instructions based on the individual's condition and the amount of cream ingested. It is crucial to have the product packaging or information leaflet available to assist healthcare providers.

In the case of a missed dose of Apityzer Cream, it is important to apply the cream as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular application schedule. Do not apply extra cream to make up for the missed dose, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to adjust your dosing schedule and ensure the best results from your treatment.

To use Apityzer Cream, gently cleanse and dry the affected skin area, then apply a thin layer of the cream directly to the skin, usually two to three times a day or as directed by your healthcare provider, taking care to avoid the eyes and mouth.

Following are the conditions when Apityzer Cream should not be used:

• Do not use if you have a known allergy or sensitivity to any of the ingredients in the cream, including the active ingredient (such as apixaban).
• Avoid using Apityzer Cream if you have a bleeding disorder or are taking blood-thinning medications, as it may increase the risk of bleeding.
• Not suitable for individuals with severe liver or kidney disease, as it may affect drug metabolism and clearance.
• Should not be applied to areas of broken skin, open wounds, or infected skin.
• Contraindicated in individuals with a history of stroke or transient ischemic attack (TIA).
• Do not use Apityzer Cream if you have a history of blood clots or deep vein thrombosis (DVT).
• Avoid using it on skin conditions like eczema, psoriasis, or severe skin irritation, as it may cause further skin irritation.
• Not recommended for individuals with a history of uncontrolled high blood pressure.

The possible side effects of Apityzer Cream may include:

• Skin irritation or redness at the application site
• Burning or stinging sensation
• Dryness or peeling of the skin
• Itching or rash
• Swelling or inflammation
• Allergic reactions (hives, difficulty breathing, swelling of the face/lips/tongue)
• Increased skin sensitivity to sunlight

Following are the precautions and warnings for Apityzer Cream:

• Avoid contact with eyes, nose, and mouth. In case of accidental contact, rinse thoroughly with water.
• Do not apply to broken or irritated skin. Discontinue use if irritation or rash occurs.
• For external use only. Do not ingest or swallow.
• Keep out of reach of children. Store in a cool, dry place, away from direct sunlight.
• Do not use if you are allergic to any of the ingredients in the cream. Check the ingredients list before use.
• If you are pregnant or breastfeeding, consult your doctor before using this medication.
• This medication may cause skin sensitivity to sunlight. Limit sun exposure and use protective measures when outdoors.

Following are the drug interactions for Apityzer Cream:

• Topical steroids or other potent anti-inflammatory drugs used concurrently may increase the risk of skin atrophy and HPA axis suppression.
• Avoid using other topical acne treatments or products containing benzoyl peroxide, resorcinol, or salicylic acid without medical advice, as this may lead to excessive skin irritation.
• The absorption of other topical medications may be altered when used with Apityzer Cream, potentially affecting their efficacy.
• Caution is advised when using the cream with oral retinoids, as it may increase the risk of local skin reactions and photosensitivity.
• The use of other topical agents with a drying effect, such as peeling agents or astringents, may exacerbate skin dryness and irritation.
• Apityzer Cream may interact with systemic medications, including certain antibiotics and retinoids, increasing the risk of adverse effects.
• Consult a doctor before using any other medications or herbal supplements concurrently to avoid potential interactions.

Following are the food interactions for Apityzer Cream:

• Grapefruit consumption should be limited while using this medication, as it may interfere with the drug's metabolism and increase the risk of side effects.
• Avoid excessive alcohol intake during treatment as it may increase skin sensitivity and reduce the cream's effectiveness.
• Fatty or oily foods may not significantly impact the cream's topical application, but a healthy diet supports overall skin health.
• Spicy foods might cause skin irritation or redness, especially if applied near the mouth or sensitive areas.
• Caffeine intake may not directly interact, but reducing it can help manage certain skin conditions.
• Avoid foods with high sugar content, as they can contribute to skin inflammation and delay healing.
• Certain dairy products might be beneficial for skin health, but consult a dermatologist for personalized advice.

Apityzer Cream should be stored in a cool and dry place, preferably at room temperature between 20-25°C (68-77°F). Keep the cream in its original packaging, tightly sealed, to protect it from light and moisture. Avoid exposing the cream to direct sunlight or storing it in the bathroom, as heat and humidity can affect its potency. Always check the expiration date, and do not use the cream if it has expired. For disposal, do not pour it down the drain or flush it; instead, follow local guidelines for medication disposal or consult a pharmacist for safe disposal practices. Keep the cream out of children's reach to prevent accidental contact or ingestion.

Following are the quick tips for Apityzer Cream:

• Apply a thin layer of the cream to the affected area as directed by your doctor.
• Clean and dry the skin before application for better absorption.
• Gently massage the cream into the skin until it is completely absorbed.
• Wash your hands after applying, unless your hands are the treated area.
• Avoid contact with eyes, nose, and mouth during application.
• Store the cream in a cool, dry place, away from direct sunlight.
• Do not cover the treated area with airtight dressings or bandages.