Vanit (400mg) 30 Tablets

Dexibuprofen, the active ingredient in the 400mg tablet, is a non-steroidal anti-inflammatory drug (NSAID) that primarily exerts its therapeutic effects through inhibiting the cyclooxygenase (COX) enzymes, particularly COX-1 and COX-2. By blocking these enzymes, dexibuprofen decreases the production of prostaglandins, which are key mediators of inflammation and pain. This inhibition of prostaglandin synthesis leads to reduced inflammation, pain relief, and fever reduction. The medication's mechanism of action is targeted at the peripheral tissues, where it suppresses the production of inflammatory mediators, thereby providing relief from symptoms associated with conditions such as arthritis, menstrual cramps, and other inflammatory conditions.

Dexibuprofen 400mg

NSAID (Non-steroidal anti-inflammatory drug)

Tablet

The following are the uses of Dexibuprofen 400mg Tablet:

• Used for relieving mild to moderate pain, such as headaches, toothaches, and menstrual cramps.
• Used for reducing inflammation and managing symptoms of rheumatoid arthritis and osteoarthritis.
• Used to lower fever and treat flu-like symptoms.
• Used for treating soft tissue injuries and sprains.
• Effective in reducing swelling and discomfort after surgical procedures.
• Used to alleviate pain and inflammation in conditions like tendonitis and bursitis.
• Provides relief from discomfort caused by muscle strains and sports injuries.

In the case of an overdose of Dexibuprofen 400mg Tablets, individuals may experience symptoms such as nausea, vomiting, abdominal pain, and gastrointestinal bleeding. The severity of these symptoms can vary depending on the amount ingested. It is important to seek medical advice promptly and provide healthcare professionals with details regarding the quantity consumed. They may recommend appropriate treatment options, including gastric lavage or administering activated charcoal to minimize further absorption. Timely intervention is essential to prevent potential complications.

In the case of a missed dose of Dexibuprofen 400mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss several doses, consult your healthcare professional for advice on how to proceed, as they may recommend adjusting your dosage or provide specific instructions for catching up on missed doses safely.

To take Dexibuprofen 400mg Tablets, swallow the tablet whole with a full glass of water, preferably with or after food, following the dosage instructions provided by your healthcare professional, typically taken once or twice a day as needed for pain relief.

Following are the conditions/situations when Dexibuprofen 400mg Tablet should not be taken:

• Avoid if you have a known allergy or hypersensitivity to Dexibuprofen or other NSAIDs (Non-Steroidal Anti-Inflammatory Drugs).
• Do not use if you have a history of gastrointestinal bleeding or perforation after taking NSAIDs.
• Contraindicated in individuals with severe heart failure or heart disease.
• Should not be used in patients with a history of asthma attacks or severe allergic reactions triggered by aspirin or other NSAIDs.
• Not recommended for individuals with active peptic ulcers or gastrointestinal bleeding.
• Avoid if you have severe kidney or liver impairment.
• Do not take if you have recently undergone coronary artery bypass graft (CABG) surgery.
• Contraindicated in individuals with a history of stroke or transient ischemic attacks (TIAs).

The side effects of Dexibuprofen 400mg Tablet may include:

• Stomach pain or upset
• Nausea and vomiting
• Diarrhea
• Dizziness or vertigo
• Headache
• Drowsiness or fatigue
• Skin rash or itching
• Increased blood pressure

Following are the precautions and warnings for Dexibuprofen 400mg Tablet:

• Do not use if you have a known allergy or hypersensitivity to Dexibuprofen or other NSAIDs (Non-Steroidal Anti-Inflammatory Drugs).
• Exercise caution in patients with a history of gastrointestinal bleeding, ulcers, or other gastrointestinal disorders, as this medication may increase the risk of bleeding.
• Patients with cardiovascular disease, hypertension, or those who have recently undergone heart surgery should use it with caution, as it may increase the risk of cardiovascular events.
• Not recommended for use in pregnant women, especially during the third trimester, due to potential harm to the fetus.
• Consult a healthcare professional before use if you have kidney or liver disease, as dosage adjustments may be necessary.
• Avoid using Dexibuprofen 400mg Tablet in combination with other NSAIDs or blood-thinning medications, as this may increase the risk of bleeding and gastrointestinal side effects.
• Discontinue use and seek medical attention if you experience severe skin reactions, difficulty breathing, or signs of anaphylaxis.

Following are the drug interactions for Dexibuprofen 400mg Tablet:

• May increase risk of bleeding when taken with anticoagulants like warfarin, clopidogrel, or aspirin.
• Can reduce the effectiveness of antihypertensive medications, including ACE inhibitors and beta-blockers.
• May increase blood levels of lithium, leading to potential lithium toxicity.
• Concurrent use with diuretics can decrease diuretic efficacy and increase the risk of renal toxicity.
• Dexibuprofen may reduce the efficacy of anti-diabetic medications, requiring careful blood sugar monitoring.
• Increased risk of gastrointestinal ulcers and bleeding when combined with corticosteroids or other NSAIDs.
• Can potentially decrease the effectiveness of certain antibiotics, such as ciprofloxacin or levofloxacin.

Following are the food interactions for Dexibuprofen 400mg Tablet:

• Alcohol consumption should be avoided as it can increase the risk of gastrointestinal bleeding and liver toxicity when combined with Dexibuprofen.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of Dexibuprofen, potentially increasing its levels in the body and the risk of side effects.
• High-fat meals may delay the absorption of Dexibuprofen, leading to a potential delay in pain relief.
• Avoid excessive caffeine intake as it can increase the risk of stomach irritation and may interfere with the absorption of Dexibuprofen.
• Avoid spicy foods as they can aggravate stomach irritation and potentially worsen symptoms.
• Dairy products may potentially reduce the absorption of Dexibuprofen, so consider separating the medication and dairy intake by a few hours.
• Antioxidant-rich foods like berries, nuts, and leafy greens may help reduce the risk of gastrointestinal side effects associated with long-term NSAID use.
• Stay well-hydrated by drinking plenty of water to reduce the risk of kidney-related side effects, especially if you have pre-existing kidney issues.

Dexibuprofen 400mg Tablets should be stored in a cool and dry place, preferably at room temperature (below 25°C). Keep the medication in its original container, tightly sealed, to ensure its integrity and protect it from light and moisture. It is crucial not to expose the tablets to excessive heat or cold, so avoid storing them in the bathroom or near hot appliances. Always check the expiration date, and if the tablets are expired or no longer needed, dispose of them responsibly. Do not flush or pour them into drainage systems; instead, follow local guidelines for pharmaceutical waste disposal. Keep the medication away from children and pets to prevent accidental consumption.

Following are the quick tips for Dexibuprofen 400mg Tablet:

• Consult your doctor before use, especially if you have a medical history or are taking other medications.
• Take the tablet with or after food to minimize stomach irritation.
• Swallow the tablet whole with a sufficient amount of water.
• Do not crush or chew the tablet.
• Maintain a gap of at least 8 hours between doses.
• Avoid taking with other NSAIDs or blood thinners.
• Inform your doctor if you have any allergies or kidney/liver issues.
• Store in a cool, dry place, away from direct sunlight.