Vechlor (0.5%) 10ml Eye Drops

Chloramphenicol, a broad-spectrum antibiotic, exerts its bactericidal effect primarily through the inhibition of protein synthesis in susceptible bacteria. It achieves this by binding to the 50S subunit of the bacterial ribosome, thereby preventing the formation of peptide bonds and subsequent protein assembly. Hydroxypropyl methylcellulose, on the other hand, is a viscous agent that forms a protective film on the ocular surface, providing lubrication and moisture retention. This combination ensures that the antibiotic remains in contact with the eye for an extended period, allowing for effective treatment of bacterial infections.

Chloramphenicol, Hydroxypropyl Methylcellulose

Antibiotic, Lubricant.

drop

The following are the uses of Chloramphenicol, Hydroxypropyl Methylcellulose Drop:

• Used for treating bacterial eye infections
• Used to prevent eye infections after eye surgery or injury
• Used for reducing inflammation and redness in the eye
• Used for providing eye lubrication and comfort
• Used for treating conjunctivitis and corneal ulcers
• Used to relieve eye dryness and irritation
• Used for preventing further eye damage and promoting healing

In the case of an overdose of Chloramphenicol or Hydroxypropyl Methylcellulose Drops, immediate medical attention is necessary. Symptoms may include nausea, vomiting, diarrhea, and in severe cases, seizures or respiratory distress. Promptly contact a healthcare professional or poison control center for guidance on managing the overdose. Quick action can help mitigate potential health risks associated with excessive ingestion of these medications.

In the case of a missed dose of Chloramphenicol, it is recommended to administer the eye drops as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra drops to make up for the missed dose. For Hydroxypropyl Methylcellulose Drop, if you miss a dose, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose and resume your regular dosing interval.

To use Chloramphenicol and Hydroxypropyl Methylcellulose Drops, gently shake the bottle, tilt your head back, and instill the prescribed number of drops into the affected eye(s) as directed by your healthcare professional, typically 1-2 drops into the eye(s) every 2-4 hours, or as instructed, ensuring accurate dosing with the provided dropper.

Following are the conditions when Chloramphenicol, Hydroxypropyl Methylcellulose Drops should not be used:

• Do not use if you have a known allergy or hypersensitivity to Chloramphenicol or any of the excipients in the eye drop formulation.
• Contraindicated in individuals with a history of serious adverse reactions to Chloramphenicol, including aplastic anemia or bone marrow suppression.
• Not suitable for individuals with known or suspected bacterial resistance to Chloramphenicol.
• Avoid using these drops if you have a viral or fungal infection in the eye, as they are only effective against bacterial infections.
• Do not use if the seal of the eye drop bottle is broken or if the solution appears discolored or cloudy.
• Not recommended for individuals with a history of eye conditions such as optic nerve disorders or corneal damage.

The side effects of Chloramphenicol, Hydroxypropyl Methylcellulose Eye Drops may include:

• Eye irritation or redness
• Burning or stinging sensation in the eye
• Blurred vision or temporary vision changes
• Eye itching or discomfort
• Increased sensitivity to light (photophobia)
• Watery eyes or excessive tearing
• Allergic reactions, such as rash, itching, or swelling around the eye

Following are the precautions and warnings for Chloramphenicol, Hydroxypropyl Methylcellulose Eye Drops:

• Do not use these eye drops if you are allergic to chloramphenicol or any other ingredients in the formulation.
• Prolonged use of chloramphenicol eye drops can lead to bacterial resistance and the potential risk of overgrowth of nonsusceptible organisms.
• These eye drops are for external use only and should not be ingested.
• Avoid wearing contact lenses while using these eye drops, as they may contain preservatives that can be absorbed by the lenses.
• If you have a history of liver or kidney disease, use with caution as these conditions may affect the metabolism and excretion of chloramphenicol.
• Discontinue use and consult a doctor if you experience severe or persistent eye irritation, redness, or vision changes.
• Keep out of reach of children. Store in a cool, dry place, away from direct sunlight.
• Do not use if the solution changes color or becomes cloudy, as this may indicate contamination.

Following are the drug interactions for Chloramphenicol, Hydroxypropyl Methylcellulose Drop:

• Chloramphenicol can interact with other antibiotics like penicillin, increasing the risk of side effects and altering the effectiveness of both drugs.
• It may reduce the effectiveness of oral contraceptives, so alternative birth control methods are recommended during treatment.
• Chloramphenicol can prolong the effects of anticoagulants, such as warfarin, requiring close monitoring of blood clotting time.
• Drugs metabolized by the liver, including certain anticonvulsants and antipsychotics, may have increased blood levels when taken with Chloramphenicol.
• Caution is advised when combining with medications affecting bone marrow function, as this may increase the risk of bone marrow suppression.
• Alcohol use should be avoided as it may increase the risk of side effects and liver toxicity.
• Hydroxypropyl Methylcellulose may slow the absorption of other medications taken concurrently, potentially affecting their effectiveness.

Following are the food interactions for Chloramphenicol, Hydroxypropyl Methylcellulose Drop:

• Avoid consuming grapefruit and grapefruit juice as they may interfere with the medication's metabolism and increase the risk of side effects.
• Alcohol consumption should be minimized or avoided as it can lead to increased drowsiness and dizziness, especially when combined with the medication's potential side effects.
• Fatty meals can delay the absorption of the medication, so it is best to take the drops on an empty stomach or as directed by your healthcare professional.
• Avoid dairy products like milk or yogurt immediately after taking the drops, as calcium can bind with the medication and reduce its effectiveness.
• Avoid caffeine-rich beverages like coffee or energy drinks, as they may increase the risk of side effects such as jitteriness and insomnia.
• Do not consume herbal supplements or alternative medicines without consulting your doctor, as some herbs may interact with the medication's effectiveness.
• Always follow the dosage instructions provided by your healthcare provider, as incorrect dosage can lead to reduced effectiveness or increased side effects.
• Inform your doctor about any dietary changes or restrictions to ensure the medication's safety and effectiveness.

Chloramphenicol, Hydroxypropyl Methylcellulose Drop should be stored in a cool and dry place, preferably at room temperature (around 25°C/77°F). Keep the dropper bottle tightly closed and protected from light. Ensure the medication is stored in its original packaging to maintain its integrity. Avoid freezing or exposing the drops to excessive heat as it may affect their potency. Dispose of any unused or expired medication responsibly by following local guidelines or consulting a pharmacist. Do not pour the medication down the drain or discard it with regular household waste; instead, utilize designated medication disposal programs or facilities to minimize environmental impact. Keep the drops out of children's reach to prevent accidental ingestion.

Following are the quick tips for this:

• Administer the eye drops as directed by your doctor for effective treatment.
• Wash your hands before using the drops to maintain hygiene.
• Tilt your head back, gently pull down your lower eyelid, and apply the prescribed number of drops into the eye.
• Avoid touching the dropper tip to your eye or any surface to prevent contamination.
• If you use other eye medications, wait at least 5 minutes before applying the next medication.
• Store the eye drops properly and keep them out of reach of children.
• Use the eye drops as directed by your eye specialist for best results.
• Ensure your hands are clean before applying the drops to prevent infection.
• Tilt your head back, gently pull down the lower eyelid, and place the prescribed number of drops into the eye.
• Refrain from rubbing or blinking immediately after applying the drops for better absorption.
• If you wear contact lenses, remove them before using the drops and wait the recommended time before reinserting them.
• Keep the bottle tightly closed and store it in a cool, dry place.