Veflox-D (0.3/0.1%) 5ml Eye Suspension

Dexamethasone, a potent synthetic corticosteroid, primarily works by suppressing inflammation and immune responses in the eye. It binds to glucocorticoid receptors in the ocular tissues, leading to the down-regulation of pro-inflammatory genes and the inhibition of various inflammatory mediators such as prostaglandins, leukotrienes, and cytokines. This reduces the signs and symptoms associated with ocular inflammation, including redness, swelling, and itching. Ofloxacin, on the other hand, is a broad-spectrum fluoroquinolone antibiotic that exerts its action by inhibiting bacterial DNA gyrase and topoisomerase IV enzymes, which are crucial for bacterial DNA replication and transcription. By preventing the replication and repair of bacterial DNA, ofloxacin effectively eliminates a wide range of bacteria that may cause eye infections.

Corticosteroid, Antibiotic.

Drop

The following are the uses of Dexamethasone, Ofloxacin Eye Drop:

• Used for reducing inflammation and treating various eye conditions, such as allergic conjunctivitis and uveitis.
• Used for treating eye infections, particularly bacterial conjunctivitis.
• Used for managing eye pain and discomfort associated with certain eye conditions.
• Used for preventing and treating eye damage caused by chemicals or radiation.
• Used for alleviating eye redness and irritation.
• Used for treating corneal ulcers or injuries.
• Used for providing short-term relief from dry eye symptoms.
• Used for supporting the healing process after eye surgeries or procedures.

In the case of an overdose of Dexamethasone or Ofloxacin Eye Drops, individuals may experience increased eye pressure, blurred vision, or eye discomfort. For Dexamethasone, symptoms can include fluid retention, weight gain, and elevated blood sugar levels. If you suspect an overdose, promptly contact a healthcare professional or a poison control center for guidance. They will provide specific instructions to address the situation effectively and ensure appropriate medical care.

In the case of a missed dose of Dexamethasone, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. For Ofloxacin Eye Drops, if you miss a dose, administer it as soon as possible. If it's almost time for your next dose, you can still apply the eye drops, but be careful not to overuse them. It is best to try to stick to your regular dosing schedule as much as possible.

To use Dexamethasone and Ofloxacin Eye Drops, gently tilt your head back, pull the lower eyelid down to create a pocket, and instill the prescribed number of drops into the eye without touching the dropper to any surfaces, then close your eyes gently and apply light pressure to the inner corner of the eye for a few seconds to help the medication absorb.

Here are the situations or conditions when Dexamethasone, Ofloxacin Eye Drops should not be used:

• Avoid using if you have a known allergy to any corticosteroids or fluoroquinolone antibiotics.
• Do not use if you have a history of hypersensitivity reactions to any of the ingredients in the eye drops.
• Contraindicated in patients with viral, fungal, or mycobacterial infections of the eye; it should only be used for bacterial infections.
• Not recommended for individuals with corneal ulcers or perforations.
• Avoid using if you have a history of glaucoma or elevated intraocular pressure (IOP).
• Do not use if you have a herpes simplex infection of the eye, as it can worsen the condition.
• Not suitable for individuals with a history of recent eye surgery, unless advised by an ophthalmologist.
• Do not use if the seal of the eye drop bottle is broken or if the solution appears discolored or contains particles.

The side effects of Dexamethasone may include:

• Increased intraocular pressure (pressure inside the eyes)
• Cataracts (clouding of the eye's lens)
• Delayed wound healing
• Thinning of the skin
• Easy bruising
• Weight gain
• Mood changes, including irritability and depression
• Sleep disturbances
• Eye burning or stinging
• Temporary blurred vision
• Eye redness or itching
• Watery eyes
• Sensitivity to light
• Dry eyes
• Headache

Following are the precautions and warnings for Dexamethasone, Ofloxacin Eye Drops:

• Do not use if you are allergic to any of the ingredients, including dexamethasone or ofloxacin.
• This medication is for external use only; do not swallow or inject it.
• Avoid wearing contact lenses while using this medication; consult your doctor if you are a contact lens wearer.
• Do not touch the dropper tip to any surface, including the eye, to prevent contamination.
• Prolonged use of corticosteroid eye drops like dexamethasone may lead to increased intraocular pressure, glaucoma, and cataract formation. Regular eye pressure checks are advised.
• Do not use if you have a history of herpes viral infections in the eye; ofloxacin may cause a reactivation of the virus.
• Discontinue use and seek medical attention if you experience eye pain, changes in vision, or signs of an allergic reaction.
• Keep out of reach of children and pets.

Following are the drug interactions for Dexamethasone and Ofloxacin Eye Drops:

• Dexamethasone can increase the risk of systemic side effects when used with other drugs that suppress the immune system, such as cyclosporine or tacrolimus.
• Concomitant use of Ofloxacin with other fluoroquinolones or certain antibiotics (e.g., erythromycin) may increase the risk of adverse reactions and reduce its effectiveness.
• Antifungal medications like ketoconazole can increase the concentration of dexamethasone, potentially leading to increased side effects.
• Dexamethasone may reduce the effectiveness of live vaccines, so vaccination schedules should be adjusted accordingly.
• Nonsteroidal anti-inflammatory drugs (NSAIDs) may increase the risk of gastrointestinal bleeding when used with dexamethasone.
• The use of Ofloxacin Eye Drops with corticosteroid eye drops may prolong the effects of the corticosteroid, potentially leading to increased ocular pressure.
• Dexamethasone can alter the blood levels of certain medications, including phenytoin, warfarin, and rifampin, requiring close monitoring.

Following are the food interactions for Dexamethasone and Ofloxacin Eye Drops:

• Avoid consuming grapefruit and grapefruit juice during treatment with Dexamethasone, as it can increase the drug levels in the body, potentially causing adverse effects.
• Alcohol intake should be limited as it may worsen side effects like dizziness and blurred vision.
• Dairy products like milk and yogurt can affect the absorption of Dexamethasone, so it's best to take the medication on an empty stomach.
• Ofloxacin Eye Drops may be affected by certain foods; it's advisable to wait at least 30 minutes after eating before administering the eye drops.
• Avoid consuming foods high in vitamin K (like spinach, kale) while using Dexamethasone, as it may reduce the medication's effectiveness.
• No known specific food interactions with Ofloxacin Eye Drops, but maintaining a healthy diet is recommended for overall eye health.
• Always consult your healthcare provider for personalized advice regarding food and medication interactions.

Dexamethasone and Ofloxacin Eye Drops should be stored in a clean, dry, and cool environment, preferably at room temperature, away from excessive heat, direct sunlight, and moisture. Keep the eye drops in their original container, tightly sealed, to maintain sterility and prevent contamination. Ensure the bottle is kept upright and do not allow the dropper tip to touch any surfaces to avoid introducing bacteria. Do not freeze the eye drops or expose them to extreme temperatures. Check the expiration date regularly, and dispose of any unused or expired medication responsibly, avoiding flushing or pouring it down the drain. Consult a pharmacist or healthcare professional for guidance on proper disposal methods to ensure environmental safety.

Following are the quick tips for Dexamethasone and Ofloxacin Eye Drops:

• Wash your hands before using the eye drops to maintain hygiene.
• Tilt your head back, gently pull down your lower eyelid, and instill the prescribed number of drops into the eye.
• Close your eyes gently and apply light pressure to the inner corner of the eye for a few seconds to prevent the medication from draining out.
• Avoid touching the dropper tip to any surface to prevent contamination.
• If using multiple eye medications, wait at least 5 minutes between applying different drops to allow proper absorption.
• Do not share your eye drops with others to prevent the spread of infection.
• Store the eye drops at room temperature, away from direct sunlight and moisture.