Velosef (250mg/5ml) 90ml Suspension

Cephradine is a first-generation cephalosporin antibiotic. It works by inhibiting the synthesis of bacterial cell walls, which is essential for the bacteria's growth and survival. Specifically, Cephradine binds to penicillin-binding proteins (PBPs) located in the bacterial cell wall, disrupting the final stages of cell wall synthesis. This leads to the formation of defective cell walls and ultimately results in the death of the bacteria. Cephradine is effective against a wide range of gram-positive and some gram-negative bacteria.

Cephradine 250mg

cephalosporin antibiotics

Syrup/Suspension

The following are the uses of Cephradine 250 mg Syrup/Suspension:

• Treatment of respiratory tract infections such as pneumonia and bronchitis caused by susceptible bacteria.
• Management of urinary tract infections, including cystitis and pyelonephritis.
• Treatment of skin and soft tissue infections like cellulitis and abscesses.
• Management of ear infections (otitis media) caused by bacteria.
• Treatment of bone and joint infections, including osteomyelitis.
• Treatment of gastrointestinal infections caused by susceptible organisms.
• Management of mild to moderate infections due to susceptible strains of bacteria.

Following are the doses of Cephradine 250 mg Syrup/Suspension:

• The usual dose for adults and children over 12 years old is 250 mg every 6 hours, up to a maximum of 4 doses per day.
• For children aged 6 to 12 years, the typical dose is 125 mg every 6 hours.
• In some cases, based on the severity of the infection or as prescribed by a healthcare provider, the dose may be adjusted.
• For more severe infections, the dose may be increased, but it is important to follow the exact instructions given by the healthcare provider.
• For pediatric dosing, always follow the specific instructions given by your doctor based on the child's weight and condition.

In case of an overdose of Cephradine 250 mg Syrup/Suspension, immediate medical attention should be sought. An overdose may lead to symptoms such as nausea, vomiting, diarrhea, or an increased risk of kidney-related issues. If too much of the medication is accidentally ingested, it is important not to induce vomiting or take any other actions without consulting a healthcare provider.

If you miss a dose of Cephradine 250 mg Syrup/Suspension, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at once to make up for the missed dose, as this may increase the risk of side effects. Always follow the dosing instructions provided by your healthcare provider and consult them if you're unsure about how to proceed after missing a dose.

To use Cephradine 250 mg Syrup/Suspension, follow the instructions provided by your healthcare provider or as indicated on the prescription label. Typically, it should be taken 2-4 times a day, depending on the condition being treated. Shake the bottle well before each dose to ensure the medication is properly mixed. Use the provided measuring device to ensure accurate dosing. You can take the syrup with or without food, but taking it with food may help reduce stomach upset. Make sure to complete the full prescribed course of treatment, even if you start feeling better, to avoid the return of the infection or the development of antibiotic resistance.

Following are the situations when Cephradine 250 mg Syrup/Suspension should not be used:

• Should not be used in individuals with a known allergy to Cephradine or any of its components.
• Contraindicated in patients who have a history of hypersensitivity reactions to cephalosporins, penicillins, or other beta-lactam antibiotics.
• Should not be used in patients with a history of severe gastrointestinal conditions, such as colitis, as Cephradine may exacerbate these conditions.
• Contraindicated in individuals with significant renal impairment without dose adjustment, as the drug is primarily excreted by the kidneys.

The side effects of Cephradine 250 mg Syrup/Suspension may include:

• Diarrhea
• Nausea
• Vomiting
• Abdominal pain
• Rash
• Itching
• Dizziness
• Headache

Serious side effects may include

• Allergic reactions (e.g., swelling, difficulty breathing)
• Severe gastrointestinal issues, such as colitis
• Changes in blood cell counts (e.g., low white blood cells or platelets)

Following are the precautions and warnings for Cephradine 250 mg Syrup/Suspension:

• Should not be used in individuals with a known allergy to Cephradine or any of its components.
• Contraindicated in patients who have a history of hypersensitivity reactions to cephalosporins or penicillins.
• Use with caution in patients with a history of renal impairment, as Cephradine is excreted by the kidneys and dose adjustments may be necessary.
• Caution is advised in individuals with a history of gastrointestinal diseases, such as colitis, as Cephradine may cause gastrointestinal disturbances.
• Patients with a history of blood disorders should be monitored, as Cephradine may cause changes in blood cell counts.
• Use with caution in pregnant or breastfeeding women; consult a healthcare provider before use.
• Always complete the full course of Cephradine even if symptoms improve to avoid developing antibiotic resistance.

Following are the drug interactions for Cephradine 250 mg Syrup/Suspension:

• Concomitant use with probenecid may increase the levels of Cephradine in the blood, which could lead to an increased risk of side effects.
• Caution is advised when using Cephradine with other antibiotics (e.g., tetracyclines), as this may affect the effectiveness of either drug.
• Oral contraceptives may have reduced effectiveness when taken with Cephradine. It's advisable to consult with your healthcare provider about alternative contraception methods.
• Anticoagulants (e.g., warfarin) may interact with Cephradine and increase the risk of bleeding. Monitoring of blood clotting may be necessary.
• The use of antacids or iron supplements close to the time of taking Cephradine may reduce the absorption of the medication, potentially decreasing its effectiveness.

Following are the food interactions for Cephradine 250 mg Syrup/Suspension:

• There are no significant food interactions with Cephradine. It can be taken with or without food.
• However, consuming Cephradine with food may help reduce the risk of gastrointestinal upset, which can occasionally occur with antibiotics.
• Alcohol should be avoided during treatment with Cephradine, as it can increase the risk of side effects such as dizziness or stomach upset.

Cephradine 250 mg Syrup/Suspension should be stored at room temperature, away from direct heat, light, and moisture. Keep the bottle tightly closed and store it in a dry place, such as a cabinet or drawer, out of the reach of children and pets to prevent accidental ingestion. Do not store the syrup in the bathroom, as the humidity may affect the quality of the medication. Be sure to check the expiration date before using the medication.For disposal, do not flush Cephradine down the toilet or pour it into a drain unless specifically instructed to do so. If you have unused or expired syrup, consult your pharmacist or healthcare provider for proper disposal instructions. Some pharmacies offer medication take-back programs, or they may provide guidance on how to safely dispose of the syrup to avoid harm to others or the environment.

Following are the quick tips for Cephradine 250 mg Syrup/Suspension:

• Take Cephradine syrup exactly as prescribed by your healthcare provider for optimal results.
• Shake the bottle well before each dose to ensure the medication is evenly mixed.
• Use a proper measuring device (e.g., oral syringe or measuring cup) to ensure accurate dosing.
• Take the medication with or without food, as advised by your healthcare provider.
• Complete the full prescribed course, even if you start feeling better, to prevent the infection from returning.
• Inform your healthcare provider if you experience any side effects such as diarrhea, rash, or unusual tiredness.
• Keep track of any missed doses and take it as soon as possible unless it’s almost time for your next dose. Never take two doses at once to make up for a missed one.