Veloxen (25/50mg) 10 Scored Tablets

Levofloxacin, a powerful antibiotic belonging to the fluoroquinolone class, exerts its therapeutic effect by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes vital for bacterial DNA replication and repair. This inhibition leads to the disruption of DNA synthesis, ultimately resulting in the death of susceptible bacteria. Specifically, levofloxacin targets the A subunit of these enzymes, forming a stable drug-enzyme-DNA complex that prevents the re-ligation of broken DNA strands, thereby inhibiting DNA replication and promoting bacterial cell death. This mechanism of action is highly effective against a broad spectrum of gram-positive and gram-negative bacteria, making levofloxacin a valuable tool in the treatment of various bacterial infections.

Levofloxacin 50mg

Fluoroquinolone antibiotic.

Tablet

The following are the uses of Levofloxacin 50mg Tablet:

• Used for treating bacterial infections such as pneumonia, bronchitis, and urinary tract infections.
• Used for controlling bacterial growth in severe cases of sinusitis and skin infections.
• Used to manage bacterial exacerbation in patients with chronic bronchitis.
• Used to treat infections in various body systems, including respiratory, skin, and urinary.
• Used for its broad-spectrum activity against a wide range of bacteria.
• Used as an alternative for patients allergic to penicillin-derived antibiotics.
• Used to prevent and treat anthrax exposure or infection.

In the case of an overdose of Levofloxacin 50mg Tablets, it is important to recognize the potential risks and take appropriate action. Symptoms of an overdose may include nausea, dizziness, and changes in heart rate or rhythm. If you suspect an overdose, seek medical advice immediately. Quick response and professional care are essential to manage any adverse effects and ensure the best possible outcome. It is crucial to act promptly and not delay seeking assistance.

In the case of a missed dose of Levofloxacin 50mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for advice, as they may recommend adjusting your dosing schedule or provide further instructions to ensure you receive the correct amount of medication.

To take Levofloxacin 50mg Tablet, swallow the tablet whole with a full glass of water, preferably at the same time each day, as directed by your healthcare professional, and ensure you complete the full course of medication as prescribed.

Here are the conditions or situations when Levofloxacin 50mg Tablet should not be used:

• Avoid if you have a known allergy to Levofloxacin or other quinolone antibiotics.
• Do not use if you have a history of myasthenia gravis, as it can worsen muscle weakness.
• Contraindicated in patients with a history of tendon disorders or tendon rupture related to previous quinolone use.
• Not recommended for individuals with epilepsy or other seizure disorders.
• Should not be used in patients with a slow or irregular heartbeat (cardiac arrhythmias).
• Avoid if you have a history of central nervous system disorders such as psychosis or severe anxiety.
• Contraindicated in patients with kidney disease or those on dialysis, as dosage adjustment is required.
• Not suitable for children and adolescents under 18 years of age due to potential risks to bone and joint development.
• Do not use if you have a deficiency of a specific enzyme called glucose-6-phosphate dehydrogenase (G6PD).

The side effects of Levofloxacin 50mg Tablet may include:

• Nausea and vomiting
• Diarrhea
• Headache
• Dizziness
• Insomnia (difficulty sleeping)
• Skin rash or itching
• Joint or muscle pain
• Increased sensitivity to sunlight

Following are the precautions and warnings for Levofloxacin 50mg Tablet:

• Do not use if you are allergic to Levofloxacin or any similar antibiotics from the fluoroquinolone class.
• This medication is not recommended for individuals with a history of myasthenia gravis, as it may worsen muscle weakness.
• Patients with a history of heart, kidney, or liver disease should use with caution and under medical supervision.
• Elderly patients may be more susceptible to side effects, especially tendon problems and irregular heart rhythm.
• Avoid excessive exposure to sunlight or UV rays as Levofloxacin can increase skin sensitivity.
• Inform your doctor if you have epilepsy or other seizure disorders before taking this medication.
• Levofloxacin may cause dizziness or lightheadedness; avoid driving or operating machinery until you know how it affects you.

Following are the drug interactions for Levofloxacin 50mg Tablet:

• May enhance the effects of anticoagulants like warfarin, increasing the risk of bleeding. Regular monitoring of coagulation parameters is necessary.
• Concomitant use with non-steroidal anti-inflammatory drugs (NSAIDs) may further enhance the risk of central nervous system (CNS) stimulation and seizures.
• Theophylline levels can be increased when used with Levofloxacin, leading to potential toxicity.
• The effectiveness of antidiabetic medications, such as insulin or oral hypoglycemic agents, may be altered, resulting in changes in blood sugar levels.
• Probenecid can decrease the elimination of Levofloxacin, leading to higher drug levels and increased risk of side effects.
• Levofloxacin may reduce the efficacy of live attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine.
• It may also interact with certain multivitamin formulations, especially those containing minerals like iron, zinc, or magnesium, reducing the absorption of Levofloxacin.

Following are the food interactions for Levofloxacin 50mg Tablet:

• Avoid caffeine-containing products like coffee, tea, energy drinks, and certain soft drinks. Caffeine can interact with Levofloxacin, leading to increased side effects and reduced drug effectiveness.
• Grapefruit and grapefruit juice should be consumed with caution. They can inhibit the metabolism of Levofloxacin, leading to increased drug levels in the blood and potential side effects.
• Alcohol should be avoided or limited during treatment. Alcohol can increase the risk of liver-related side effects and may also reduce the effectiveness of the medication.
• Dairy products like milk, yogurt, and cheese may decrease the absorption of Levofloxacin. Consider taking the medication 2 hours before or after consuming dairy.
• Avoid high-fat meals as they may delay the absorption of Levofloxacin, affecting its effectiveness.
• Iron-rich foods and supplements may interfere with Levofloxacin absorption. Take the medication 2 hours before or after consuming iron supplements or iron-rich meals.
• Antacids containing magnesium or aluminum may decrease the absorption of Levofloxacin. Separate the intake of these antacids and the medication by at least 2 hours.
• Vitamin and mineral supplements, especially those containing calcium, zinc, or iron, can interact with Levofloxacin. Consult your healthcare provider for appropriate timing and dosage adjustments.

Levofloxacin 50mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. The medication packaging should be kept tightly sealed to maintain its integrity. It is crucial not to store the tablets in the bathroom or kitchen, as these areas may expose them to heat and moisture, potentially affecting their effectiveness. Always check the expiration date before using the medication, and properly dispose of any unused or expired tablets. Do not dispose of them by flushing or pouring them down the drain; instead, consult a pharmacist or healthcare professional for safe disposal methods. Keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Levofloxacin 50mg Tablet:

• Take the tablet as directed by your doctor, usually once or twice daily.
• Swallow the tablet whole with a full glass of water, do not crush or chew.
• Maintain a consistent time for taking the tablet each day.
• Ensure you complete the full prescribed course, even if you feel better.
• Avoid excessive sunlight and use sunscreen when outdoors during treatment.
• Stay well-hydrated while taking this medication.
• Inform your doctor about all medications you are currently taking.