Veloxen (400mg) 5 Tablets

Moxifloxacin 400mg Tablet exerts its antibacterial effect by inhibiting DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, and repair. It binds to these enzymes, preventing them from unwinding and supercoiling DNA, which ultimately leads to the disruption of bacterial DNA synthesis and cell death. This mechanism selectively targets bacterial topoisomerases, resulting in a potent and broad-spectrum antibacterial activity against a wide range of Gram-positive and Gram-negative pathogens. Moxifloxacin's unique structure allows it to maintain high activity against bacteria that have developed resistance to other antibiotics, making it effective in treating various infections.

Fluoroquinolone antibiotic.

Tablet

The following are the uses of Moxifloxacin 400mg Tablet:

• Used for treating acute bacterial sinusitis, providing relief from symptoms like facial pain and nasal congestion.
• Used for effectively managing community-acquired pneumonia, helping to clear lung infections.
• Used for treating chronic bronchitis exacerbations, reducing inflammation and improving breathing.
• Used for addressing acute bacterial exacerbations in cystic fibrosis patients, supporting respiratory health.
• Used for combating skin infections like cellulitis and folliculitis, promoting skin healing.
• Used for managing certain eye infections, including conjunctivitis and corneal ulcers.
• Used for preventing and controlling post-exposure inhalation anthrax, as part of a comprehensive treatment plan.

In the case of an overdose of Moxifloxacin 400mg Tablets, it is important to recognize the potential severity of this situation. Overdose symptoms may include dizziness, headache, and gastrointestinal issues. Promptly seek medical assistance and inform healthcare professionals about the overdose, as they can provide necessary guidance and treatment. They may recommend supportive care and monitor for any adverse effects, ensuring the patient's well-being and recovery. Immediate action is vital in such cases.

In the case of a missed dose of Moxifloxacin 400mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to adjust your medication regimen. It is recommended to set reminders or alarms to help you remember to take your medication at the correct times.

To take Moxifloxacin 400mg Tablet, swallow the tablet whole with a full glass of water, preferably at the same time each day, as directed by your healthcare professional, ensuring you complete the full course of medication as prescribed.

Here are the conditions and situations when Moxifloxacin 400mg Tablet should not be taken:

• Avoid if you have a known allergy to Moxifloxacin or other quinolone antibiotics.
• Do not use if you have a history of myasthenia gravis as it can worsen muscle weakness.
• Contraindicated in individuals with a history of tendon disorders or tendon rupture related to previous quinolone therapy.
• Not suitable for patients with epilepsy or other seizure disorders.
• Should not be used in patients with a slow or irregular heartbeat (cardiac arrhythmias).
• Avoid if you have a personal or family history of prolonged QT interval or heart rhythm problems.
• Do not administer to children, adolescents, or young adults due to the risk of bone and joint development issues.
• Contraindicated in patients with severe liver disease or liver failure.
• Should not be used in patients with a history of sensitivity to light (photosensitivity) or sunburn reactions.

The side effects of Moxifloxacin 400mg Tablet may include:

• Diarrhea
• Nausea and vomiting
• Dizziness
• Headache
• Skin rash or itching
• Confusion
• Sensitivity to sunlight
• Changes in blood sugar levels

Following are the precautions and warnings for Moxifloxacin 400mg Tablet:

• Avoid using Moxifloxacin if you are allergic to any quinolone antibiotics, as it may cause severe allergic reactions.
• This medication can cause tendonitis or tendon rupture, especially in individuals over 60 years old, so discontinue use and seek medical attention if you experience tendon pain or swelling.
• Moxifloxacin can affect the central nervous system, causing dizziness or lightheadedness. Avoid driving or operating machinery until you know how the medication affects you.
• It may cause liver damage; regular monitoring of liver function is recommended during treatment.
• Patients with a history of epilepsy or other seizure disorders should use it with caution as it may lower the seizure threshold.
• Not recommended for pregnant or breastfeeding women due to potential risks to the fetus or infant.
• May cause diarrhea, which can be severe. Stop using and consult a doctor if you experience persistent or severe diarrhea during treatment.
• Consult your doctor if you have a history of heart rhythm problems or if you are taking other medications that can affect heart rhythm.

Following are the drug interactions for Moxifloxacin 400mg Tablet:

• Concomitant use with other antibiotics like clindamycin or aminoglycosides can increase the risk of neuromuscular blockade and respiratory complications.
• Moxifloxacin may lower blood sugar levels, so careful monitoring is required when used with antidiabetic medications.
• Theophylline levels can be increased when taken with Moxifloxacin, requiring dosage adjustments.
• Non-steroidal anti-inflammatory drugs (NSAIDs) might enhance the risk of central nervous system (CNS) stimulation and seizures when combined with Moxifloxacin.
• Probenecid can reduce the elimination of Moxifloxacin, leading to increased drug levels in the body.
• Antacids containing aluminum, magnesium, or calcium can decrease the absorption of Moxifloxacin, so they should be taken at least 4 hours apart.
• The use of Moxifloxacin with other drugs that prolong the QT interval, such as certain antipsychotics or antiarrhythmics, can increase the risk of cardiac arrhythmias.

Following are the food interactions for Moxifloxacin 400mg Tablet:

• Avoid excessive caffeine intake, as Moxifloxacin may increase the effects of caffeine, leading to nervousness and rapid heartbeat.
• Limit dairy products and calcium-rich foods/supplements as they can affect the absorption of Moxifloxacin, reducing its effectiveness.
• Avoid grapefruit and grapefruit juice, as they may increase Moxifloxacin levels in the blood, potentially leading to an increased risk of side effects.
• Alcohol consumption should be minimized or avoided as it may increase the risk of liver-related side effects and central nervous system side effects.
• High-fat meals may delay the absorption of Moxifloxacin, so it is best to take the medication on an empty stomach.
• Stay hydrated and maintain a balanced diet to support overall health while taking this medication.
• Consult your healthcare provider for specific dietary recommendations and any necessary adjustments during Moxifloxacin treatment.

Moxifloxacin 400mg Tablets should be stored in a secure and dry location, away from direct sunlight, moisture, and heat. Maintain the tablets in their original packaging, ensuring the container is tightly sealed to prevent exposure to air and contamination. It is crucial to keep the medication out of the reach of children and pets. Regularly check the expiration date, and if the tablets are expired or no longer needed, dispose of them responsibly. Do not dispose of them via household waste or sewage systems; instead, follow local guidelines or consult a pharmacist for appropriate disposal methods to minimize environmental impact.

Following are the quick tips for Moxifloxacin 400mg Tablet:

• Take the tablet as directed by your doctor, typically once daily.
• Swallow the tablet whole with a full glass of water, preferably on an empty stomach.
• Maintain a consistent time for taking the medication each day.
• Avoid taking antacids, iron supplements, or multivitamins within 6 hours of taking the tablet.
• Complete the full prescribed course, even if you feel better early on.
• Inform your doctor if you have a history of myasthenia gravis or tendon disorders.
• Store the medication at room temperature, away from moisture and light.