Ventolin (2mg) 120ml Syrup

Salbutamol syrup/suspension, a beta-2 adrenergic agonist, exerts its therapeutic effects primarily through stimulation of beta-2 receptors in the lungs. When administered, it binds to these receptors in the bronchial smooth muscles, leading to relaxation of the airways. This mechanism triggers a series of intracellular events, including activation of adenylate cyclase, increased production of cyclic AMP (cAMP), and subsequent activation of protein kinase A. These events result in the phosphorylation of specific proteins involved in smooth muscle contraction, ultimately leading to bronchodilation. By relaxing the bronchial smooth muscles, Salbutamol effectively relieves bronchospasm, reduces airway resistance, and increases airflow to the lungs, thereby improving respiratory function and alleviating symptoms associated with conditions such as asthma and chronic obstructive pulmonary disease (COPD).

Bronchodilator.

Suspension

The following are the uses of Salbutamol Syrup/Suspension:

• Used for relieving asthma symptoms and preventing asthma attacks.
• Used for treating chronic obstructive pulmonary disease (COPD) and opening up the airways.
• Used for managing exercise-induced bronchoconstriction, allowing easier breathing during physical activity.
• Used for treating wheezing and shortness of breath in various respiratory conditions.
• Used for providing quick relief during asthma flare-ups or sudden breathing difficulties.
• Used for reducing inflammation in the airways, making breathing easier.
• Used for preventing airway spasms and maintaining better lung function.

To be taken as per doctor's prescription

In the case of an overdose of Salbutamol Syrup/Suspension, individuals may experience symptoms such as rapid heart rate, tremors, nervousness, and headaches. Other signs can include nausea, dizziness, and muscle cramps. It is crucial to seek medical advice promptly, as excessive consumption can lead to more severe effects on the cardiovascular and nervous systems. Prompt intervention and support from healthcare professionals are essential to manage and mitigate the impact of an overdose.

In the case of a missed dose of Salbutamol Syrup/Suspension, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or using a pill organizer to help you stay on track with your medication regimen.

To use Salbutamol Syrup/Suspension, shake the bottle well, then measure the prescribed dose with a measuring cup or oral syringe, and take it orally as directed by your healthcare professional, typically two to four times a day, with or without food, ensuring you follow the dosage instructions for your age and medical condition.

Following are the conditions/situations when Salbutamol Syrup/Suspension should not be used:

• Do not use if the patient has a known allergy or hypersensitivity to Salbutamol or related beta-adrenergic medications.
• Contraindicated in patients with a history of severe cardiovascular disorders, including severe or uncontrolled high blood pressure, heart rhythm problems (arrhythmias), or coronary artery disease.
• Should not be used in patients with a history of severe or uncontrolled asthma attacks or status asthmaticus.
• Not recommended for individuals with diabetes, as it may mask the symptoms of low blood sugar.
• Avoid in patients with closed-angle glaucoma.
• Do not use in patients with a history of seizures or if they are taking medications that lower the seizure threshold.
• Contraindicated in individuals with an overactive thyroid (hyperthyroidism).
• Should not be given to infants or children under 2 years of age without medical advice.

The side effects of Salbutamol Syrup/Suspension may include:

• Restlessness or tremors
• Headache
• Nausea and vomiting
• Dry mouth and throat irritation
• Muscle cramps
• Rapid heart rate (tachycardia)
• Palpitations
• Dizziness or lightheadedness

Following are the precautions and warnings for Salbutamol Syrup/Suspension:

• Do not use in patients with a known allergy to salbutamol or related beta-adrenergic medications.
• This medication may cause paradoxical bronchospasm. Discontinue use if this occurs.
• Patients with cardiovascular disorders, hypertension, diabetes, or hyperthyroidism should use with caution and under medical supervision.
• Salbutamol can cause hypokalemia (low potassium levels); monitor potassium levels, especially in those at risk.
• May cause nervousness, tremors, or dizziness. Avoid activities requiring alertness if affected.
• Not recommended for use in children under 6 months of age.
• Consult a doctor before use during pregnancy and breastfeeding.

Following are the drug interactions for Salbutamol Syrup/Suspension:

• Concurrent use with other beta-agonists may increase the risk of cardiovascular side effects such as tachycardia, palpitations, and tremors due to additive sympathomimetic effects.
• Salbutamol may interact with non-selective beta-blockers (e.g., propranolol), which could reduce its bronchodilatory effects and worsen asthma symptoms.
• Use with diuretics (e.g., furosemide) may increase the risk of hypokalemia (low potassium levels), which can be exacerbated by Salbutamol’s potassium-lowering effects.
• The combination of Salbutamol with monoamine oxidase inhibitors (MAOIs) or tricyclic antidepressants (TCAs) may increase the risk of cardiovascular side effects such as hypertension, tachycardia, and arrhythmias.
• Caution is needed when using Salbutamol with other sympathomimetic drugs (e.g., pseudoephedrine), as it may increase the risk of overstimulation of the cardiovascular system.
• The effectiveness of Salbutamol may be reduced when combined with certain anti-hypertensive medications, including beta-blockers, as they can oppose the bronchodilatory effects of Salbutamol.
• When taken with other medications that cause hypokalemia (e.g., corticosteroids), the potassium-lowering effects of Salbutamol may be enhanced, increasing the risk of arrhythmias.
• The use of Salbutamol with corticosteroids, such as inhaled or oral steroids, may increase the risk of adverse effects like hyperglycemia, particularly in patients with diabetes.
• Caution should be used when combining Salbutamol with other drugs that affect the QT interval (e.g., some antiarrhythmics), as this may increase the risk of arrhythmias.
• Salbutamol may interact with certain antidepressants (e.g., selective serotonin reuptake inhibitors), potentially increasing the risk of serotonin syndrome when used in high doses or with other serotoninergic drugs.

Following are the food interactions for Salbutamol Syrup/Suspension:

• Consuming Caffeine-rich foods and beverages like coffee, tea, or energy drinks should be limited as they can increase heart rate and may cause nervousness or shakiness when combined with Salbutamol.
• Avoid Grapefruit and its juice as it can interfere with the metabolism of Salbutamol, leading to increased drug levels and potential side effects.
• Alcohol intake should be minimized as it may enhance the side effects of Salbutamol, including dizziness and lightheadedness.
• High-potassium foods like bananas, oranges, and spinach should be consumed in moderation as Salbutamol can cause potassium levels to rise.
• Avoid high-sugar meals and drinks as they can reduce the effectiveness of Salbutamol and potentially worsen respiratory symptoms.
• Chocolate may contain compounds that can interfere with Salbutamol's action, so it's best to limit its consumption.
• Dairy products might temporarily increase mucus production, which could potentially affect the effectiveness of Salbutamol.
• Always stay well-hydrated to ensure optimal medication absorption and respiratory function.

Salbutamol Syrup/Suspension should be stored in a secure location, away from direct sunlight and at room temperature, ensuring it remains in its original container with the cap tightly sealed to maintain its integrity and prevent contamination. Avoid exposing it to extreme temperatures, including heat sources like radiators or stoves, as this can impact the medication's effectiveness. Always be mindful of the expiration date, and when disposing of the medication, do not flush it or pour it down the drain; instead, seek guidance from a pharmacist or healthcare professional for safe disposal practices. Keep the medication out of children's reach to prevent accidental consumption.

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Following are the quick tips for Salbutamol Syrup/Suspension:

• Ensure you understand the prescribed dosage and administration instructions from your doctor or pharmacist.
• Shake the bottle vigorously before each use to ensure proper medication distribution.
• Administer the syrup with a clean measuring cup or spoon to ensure accurate dosing.
• Consume the syrup immediately after measuring to prevent medication loss.
• Store the syrup at room temperature, away from direct sunlight and moisture.
• Regularly check the expiration date and discard any expired medication.
• Inform your healthcare provider if you experience any side effects or if your symptoms worsen.
• Do not share your medication with others, even if they have similar symptoms.