Vermol 30ml Suspension

Mebendazole, the active ingredient in the 100mg syrup/suspension, acts by selectively inhibiting microtubule polymerization and assembly, which is vital for the survival and reproduction of susceptible parasites. It binds to the colchicine-sensitive site on β-tubulin, disrupting the microtubule structure and function. This interference leads to the immobilization and eventual death of the susceptible helminths by preventing glucose uptake, ATP production, and blocking the transport of secretory vesicles. Mebendazole primarily targets the adult stages of intestinal helminths, causing their paralysis and subsequent elimination from the body.

Mebendazole 100mg

Anthelmintic.

Suspension

The following are the uses of Mebendazole 100mg Syrup/Suspension:

• Used for treating intestinal worm infections such as roundworm, hookworm, and whipworm.
• Used for managing pinworm (threadworm) infections, especially in children.
• Used to eliminate or control tapeworm infestations.
• Used for the treatment of hydatid disease caused by tapeworm larvae.
• Used to prevent and control parasitic infections during travel to endemic areas.
• Used as part of mass deworming programs to reduce worm burden in communities.
• Used for the relief of symptoms associated with worm infections, including abdominal pain and diarrhea.

In the case of an overdose of Mebendazole 100mg Syrup/Suspension, symptoms may include nausea, vomiting, dizziness, and in severe cases, seizures or loss of consciousness. Prompt medical attention is necessary to manage the overdose effectively. Treatment may involve gastric lavage to remove the medication from the stomach, as well as supportive care to address any adverse effects. It is important to seek medical advice for proper management and to prevent potential complications.

In the case of a missed dose of Mebendazole 100mg Syrup/Suspension, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for advice on how to proceed and to ensure the treatment remains effective. It's crucial to adhere to the prescribed dosage and timing for optimal results.

To administer Mebendazole 100mg Syrup/Suspension, shake the bottle well, then measure the prescribed dose with a dosing spoon or oral syringe, and take it orally once or twice a day as directed by your healthcare provider, ensuring that it is taken consistently either with or without food for the duration of the treatment period.

Here are the conditions or situations when Mebendazole 100mg Syrup/Suspension should not be used:

• Do not use in individuals with a known allergy or hypersensitivity to Mebendazole or other similar anthelmintic medications.
• Contraindicated in patients with liver disease or known liver problems.
• Should not be used in individuals with a history of blood disorders or decreased bone marrow function.
• Not suitable for individuals with a known allergy to other ingredients in the suspension formulation.
• Avoid in patients with a history of seizures or epilepsy.
• Do not use in children under 2 years of age due to potential risks.
• Contraindicated during pregnancy, especially in the first trimester.
• Not recommended for breastfeeding mothers.

The side effects of Mebendazole 100mg Syrup/Suspension may include:

• Stomach pain or cramps
• Diarrhea
• Nausea and vomiting
• Headache
• Dizziness
• Itching or rash
• Fever
• Hair loss (rarely)

Following are the precautions and warnings for Mebendazole 100mg Syrup/Suspension:

• Mebendazole should not be used in patients with known hypersensitivity or allergy to the drug or its components.
• This medication is not recommended for individuals with liver disease or blood disorders, as it may worsen these conditions.
• Mebendazole should be used with caution in elderly patients, as they may be more susceptible to side effects.
• It is important to complete the full course of treatment, even if symptoms disappear after a few days.
• Avoid alcohol consumption during treatment as it may increase the risk of side effects.
• Mebendazole may cause dizziness or drowsiness; patients should avoid driving or operating heavy machinery until they know how the medication affects them.
• Consult a doctor if you are pregnant, planning to become pregnant, or breastfeeding, as Mebendazole may not be suitable in these cases.
• Keep this medication out of reach of children and pets.

Following are the drug interactions for Mebendazole 100mg Syrup/Suspension:

• Avoid co-administration with metronidazole, as it may increase the risk of neurotoxicity.
• Mebendazole may reduce the effectiveness of oral contraceptives, so alternative contraception methods are recommended.
• It can lower plasma concentrations of dexamethasone, potentially reducing its efficacy.
• The syrup may interact with cimetidine, increasing plasma levels of Mebendazole.
• Co-administration with other drugs that affect CYP3A4 enzyme activity should be done with caution, as it may alter Mebendazole's metabolism.
• May decrease the effectiveness of antacid medications, and should be taken at least 2 hours apart.
• Mebendazole may increase the risk of bleeding when taken with anticoagulant medications.

Following are the food interactions for Mebendazole 100mg Syrup/Suspension:

• Avoid consuming grapefruit or grapefruit juice as it can interfere with the medication's metabolism and potentially increase Mebendazole levels in the blood, leading to a higher risk of side effects.
• Alcohol consumption should be avoided as it can reduce the effectiveness of Mebendazole and increase the risk of liver-related side effects.
• High-fat meals may delay the absorption of Mebendazole, so it is best to take the medication on an empty stomach for optimal absorption.
• Avoid dairy products like milk, cheese, and yogurt for at least one hour after taking Mebendazole, as calcium can bind to the medication and reduce its effectiveness.
• Vitamin C-rich foods like citrus fruits and broccoli may decrease the absorption of Mebendazole, so it is advisable to consume them at a different time than the medication.
• Mebendazole may decrease the absorption of Vitamin B12, so consider taking a supplement or increasing your intake of B12-rich foods like meat, fish, and eggs.
• Avoid caffeine-containing beverages like coffee and energy drinks, as they can increase the medication's side effects, particularly nervousness and insomnia.
• Mebendazole may interact with herbal supplements, especially those that affect the liver, so consult your healthcare provider before taking any herbal remedies alongside this medication.

Mebendazole 100mg Syrup/Suspension should be stored in a secure location, maintaining a cool and dry environment, ideally at room temperature, ensuring protection from direct sunlight and moisture. It is crucial to keep the medication tightly sealed within its original packaging to maintain its integrity and prevent contamination. Avoid storing it in bathrooms or areas exposed to heat, as temperature fluctuations can compromise its effectiveness. Regularly check the expiration date, and for disposal, do not flush or pour it down the drain; instead, consult a pharmacist or healthcare professional for appropriate disposal methods. Always keep medicines out of children's reach to prevent accidental consumption.

Following are the quick tips for Mebendazole 100mg Syrup/Suspension:

• Consult a healthcare professional for the correct dosage and duration of treatment.
• Shake the bottle vigorously before each use to ensure proper medication distribution.
• Administer the syrup with a measuring cup or oral syringe for accurate dosing.
• Ensure you or your child completes the full course of medication as prescribed.
• Avoid sharing medication to prevent the spread of infections.
• Store the syrup at room temperature, away from direct sunlight and moisture.
• Dispose of any unused or expired medication safely and responsibly.