VICRYL 4/0 22MM (VCP310H) ETHICON

Polyglactin 22, a type of absorbable synthetic surgical suture, exhibits its mechanism of action through a carefully designed process of hydrolysis and absorption by the body's tissues. When implanted, the polyglactin filaments gradually undergo controlled degradation through hydrolysis, primarily initiated by water molecules present in the surrounding tissue. This hydrolysis process breaks down the long polymer chains of polyglactin into smaller, water-soluble fragments. The body's natural processes then clear these byproducts, resulting in the suture's absorption over time. The rate of absorption is carefully tailored to provide sufficient strength for wound support during the critical healing period, typically lasting several weeks, after which the suture material is safely absorbed, leaving the healed tissue intact.

Absorbable synthetic suture.

Surgical Surgical Suturess

The following are the uses of Polyglactin 22 Surgical:

• Used for suturing and repairing soft tissue, including muscle, fascia, and skin.
• Used for general surgery procedures, especially in areas with high tissue stress.
• Used for gynecological surgeries, providing support for weakened tissues.
• Used for pediatric surgeries, offering secure wound closure with minimal tissue reaction.
• Used for orthopedic procedures, aiding in the repair of tendons, ligaments, and bone flaps.
• Used for gastrointestinal surgeries, ensuring secure anastomoses and tissue approximation.
• Used for vascular surgeries, providing reliable vessel repair and ligation.

In the case of an overdose of Polyglactin 22 Surgical Sutures, it is important to note that this is a medical device and not a medication. Overdose typically does not apply in this context. However, if there is an adverse reaction or excessive use of these sutures, it is essential to seek medical advice promptly. The healthcare provider will assess the situation and provide appropriate guidance to address any potential complications related to the use of Polyglactin 22 sutures.

In the case of a missed dose of Polyglactin 22 Surgical, it is important to contact your healthcare provider or surgeon for guidance. They will advise you on the appropriate course of action, as the decision to administer a late dose or adjust the dosage schedule will depend on the specific surgical procedure and your individual health status. Do not attempt to double the dose or take extra medication to make up for the missed dose without consulting a medical professional.

To use Polyglactin 22 Surgical, administer the prescribed dosage by subcutaneous or intramuscular injection, following the instructions provided by your healthcare professional, ensuring proper hygiene and aseptic techniques for safe administration.

Following are the conditions when Polyglactin 22 Surgical Sutures should not be used:

• Not recommended for patients with a known allergy to Polyglactin 22 or any absorbable synthetic materials.
• Contraindicated in individuals with active infection at the site of implantation.
• Should not be used in patients with known sensitivity to lactide or glycolide.
• Not suitable for surgical procedures where extended tissue approximation is required due to its rapid absorption rate.
• Contraindicated in patients with conditions that may impair wound healing, such as compromised immune systems or connective tissue disorders.
• Should not be used in patients with a history of adverse reactions to similar surgical sutures.

The side effects of Polyglactin 22 Surgical Sutures may include:

• Swelling, redness, and pain at the suture site
• Infection or abscess formation
• Allergic reactions, such as itching, rash, or hives
• Tissue damage or necrosis
• Seroma (fluid accumulation)
• Delayed wound healing
• Suture granuloma (inflamed tissue around the suture)
• Temporary loss of sensation near the suture

Following are the precautions and warnings for Polyglactin 22 Surgical:

• It should only be used for surgical purposes under the supervision of a qualified healthcare professional.
• Not suitable for use in individuals with a known hypersensitivity or allergy to Polyglactin 22 or any related compounds.
• Must be used with caution in patients with compromised immune systems as it may increase the risk of infection.
• Patients with a history of wound healing problems or chronic diseases should be closely monitored.
• Avoid using in patients with severe bleeding disorders or those on anticoagulant therapy.
• Ensure proper wound care and management to prevent infection and other complications.
• Pregnant and breastfeeding women should consult their doctor before using this product.

Following are the drug interactions for Polyglactin 22 Surgical:

• It is generally considered safe for use with most medications as it is an absorbable suture material and is not systemically absorbed.
• No known significant drug interactions have been reported with Polyglactin 22.
• However, it is always advisable to inform healthcare professionals about all medications you are taking, including over-the-counter drugs and supplements, to ensure safe and effective treatment.
• Anticoagulant medications, Patients on blood thinners might have an increased risk of bleeding at the surgical site.
• Drugs affecting wound healing, Medications like corticosteroids or immunosuppressants may interfere with the body's ability to heal wounds.
• Topical antiseptics or disinfectants, Prolonged exposure to certain antiseptic solutions can potentially weaken the suture material.
• Antibiotic, While not a direct interaction, the choice of antibiotics for postoperative care should consider the suture material's compatibility to prevent suture-related infections.
• Local anesthetics, In rare cases, local anesthetics may interact with the body's response to the suture material.

Following are the food interactions for Polyglactin 22 Surgical:

• Polyglactin 22 Surgical is not meant for oral consumption, and therefore, direct food interactions are not applicable.
• This medication is used topically or as a surgical suture, and its effects are localized to the application site.
• Alcohol is not known to interact directly with Polyglactin 22, but it's advisable to avoid excessive alcohol consumption during the healing process to promote optimal wound healing.
• There is no specific dietary restriction associated with the use of Polyglactin 22 Surgical.
• Patients can generally maintain their regular diet unless advised otherwise by their healthcare provider based on their overall health condition.
• Maintaining a balanced diet with adequate protein, vitamins, and minerals can support the body's healing process.
• Certain foods that promote inflammation or irritate the gastrointestinal system might be avoided in case of post-surgical complications, but this is not a direct interaction with Polyglactin 22.
• Always follow the instructions provided by your healthcare professional regarding wound care, dietary recommendations, and any specific precautions related to your surgery.

Polyglactin 22 Surgical Sutures should be stored in a controlled environment, specifically a cool and dry place, with temperatures ranging from 20°C to 25°C (68°F to 77°F). Protect the sutures from direct sunlight, moisture, and heat sources as extreme temperatures can compromise their integrity. Store them in their original packaging, ensuring a tight seal to maintain sterility and prevent contamination. Always check the expiration date before use, and properly dispose of any unused or expired sutures. Do not flush them or dispose of them in regular trash; instead, follow local medical waste disposal guidelines or consult healthcare professionals for appropriate disposal methods. Keep these sutures out of the reach of children to prevent accidental contact or ingestion.

Following are the quick tips for Polyglactin 22 Surgical:

• Store sutures in a cool, dry place, away from direct sunlight.
• Check the expiration date before use and ensure the packaging is intact.
• Use sterile techniques when handling sutures to prevent infection.
• Follow the recommended suture removal schedule provided by your healthcare professional.
• Keep the wound clean and dry during the healing process.
• Avoid strenuous activities that may put tension on the sutures.
• Monitor the wound for any signs of infection and seek medical attention if needed.
• Consult your doctor if you have any concerns or experience unusual symptoms.