Vilgo-D Pus (2000IU) 5ml Oral Drops

Cholecalciferol, also known as vitamin D3, primarily works by aiding in the absorption and metabolism of calcium and phosphorus in the body. When administered, cholecalciferol is converted in the liver and kidneys to form the active hormone calcitriol (1,25-dihydroxyvitamin D3). This active form binds to vitamin D receptors in various tissues, primarily in the intestine, kidneys, and bones. It promotes calcium absorption in the small intestine by increasing the expression of calcium-binding proteins, allowing for more efficient uptake of calcium from the diet. In the kidneys, calcitriol regulates calcium and phosphorus reabsorption, maintaining proper mineral balance. Additionally, it stimulates osteoclast activity, promoting bone resorption and the release of calcium into the bloodstream, which is crucial for maintaining calcium homeostasis and supporting bone health.

Cholecalciferol 2,000iu

Vitamin D supplement

Drop

The following are the uses of Cholecalciferol 2,000iu Drop:

• Used for preventing and treating low levels of calcium or phosphate in the blood caused by certain disorders (e.g., hypoparathyroidism, pseudohypoparathyroidism, familial hypophosphatemia) or by removal of the parathyroid glands (sometimes done in patients undergoing thyroid surgery).
• Used for maintaining calcium and phosphate levels in patients whose kidneys or parathyroid glands (glands in the neck that release natural substances to control the body's calcium levels) are not working normally.
• Used for treating rickets (softening and weakening of bones in children, often caused by vitamin D deficiency) and a bone-thinning disorder called osteoporosis (mainly in older women).
• Used for treating a type of bone disorder that occurs in some people with kidney problems, called renal osteodystrophy.
• Used for preventing falls and fractures in people at risk for osteoporosis.
• Used for treating a bone disorder called osteomalacia (softening of bones in adults, often caused by vitamin D deficiency) in people with kidney disease who are not undergoing dialysis (a procedure to filter waste products from the blood).
• Used for preventing and treating bone changes in people with advanced breast cancer or overactive parathyroid glands (hyperparathyroidism).
• Used for increasing the body's ability to absorb calcium in people who cannot get enough calcium from their diets due to a medical condition called malabsorption syndrome.

In the case of an overdose of Cholecalciferol 2,000iu Drops, it is important to recognize the potential risks. Excessive intake may lead to symptoms such as nausea, vomiting, and an elevated calcium level in the blood. If you suspect an overdose, it is advisable to seek medical advice promptly. A healthcare professional can provide guidance and determine the appropriate course of action, which may include monitoring and supportive care. Timely intervention can help manage any adverse effects effectively.

In the case of a missed dose of Cholecalciferol 2,000 IU Drops, it is recommended to take the missed dose as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. It's important to maintain a consistent routine with this medication, but if you miss a dose occasionally, there is no cause for concern. Just resume your regular dosing schedule and ensure you take the medication as prescribed.

To use Cholecalciferol 2,000iu Drops, administer the prescribed number of drops directly into the mouth or as instructed by your healthcare provider, typically once a day or as directed.

Here are the situations when Cholecalciferol 2,000 IU drops should not be used:

• Do not use if you have a known allergy or hypersensitivity to Cholecalciferol or any of the excipients in the formulation.
• Avoid using this supplement if you have elevated calcium levels in your blood (hypercalcemia) or urine (hypercalciuria).
• Do not administer Cholecalciferol drops to infants with a history of sensitivity or allergies to any vitamins or any of the excipients.
• Not recommended for individuals with conditions causing calcium accumulation in tissues (calcification), such as arteriosclerosis.
• Avoid using this supplement if you have a history of kidney stones or kidney disease.
• Should not be used in individuals with Williams Syndrome, a genetic disorder affecting multiple systems.
• Contraindicated in those with hypervitaminosis D, a condition of abnormally high vitamin D levels.

Side effects of Cholecalciferol 2,000 IU Drop:

• Nausea
• Vomiting
• Constipation
• Weakness
• Loss of appetite
• Dry mouth
• Thirst
• Increased urination
• Fatigue
• Weight loss
• Headache
• Metallic taste
• Elevated blood calcium levels (hypercalcemia)

Following are the precautions and warnings for Cholecalciferol 2,000 IU Drop:

• Do not exceed the recommended dosage as high doses can lead to vitamin D toxicity.
• Regular monitoring of vitamin D levels is advised, especially in individuals with a history of kidney or liver disease.
• Patients with hypercalcemia (high calcium levels) should exercise caution and consult a healthcare professional before use.
• Those with a history of kidney stones or hypercalciuria (high urine calcium) should be closely monitored during treatment.
• Individuals with malabsorption syndromes may require higher doses, and their response to treatment should be monitored.
• This medication should be used with caution in patients with cardiovascular disease, as vitamin D may affect calcium metabolism.
• Elderly individuals may be more susceptible to vitamin D toxicity, so close monitoring is essential.
• Always consult a healthcare provider before using this medication if you are pregnant, planning to become pregnant, or breastfeeding.

Following are the drug interactions for Cholecalciferol 2,000 IU Drop:

• Anticonvulsants like phenobarbital, phenytoin, and carbamazepine can reduce the effectiveness of Cholecalciferol by increasing its metabolism.
• Thiazide diuretics may enhance the effect of vitamin D, potentially leading to hypercalcemia.
• Cholestyramine and colestipol can decrease the absorption of vitamin D when taken simultaneously.
• Orlistat, a weight-loss medication, may reduce the absorption of fat-soluble vitamins, including vitamin D.
• Mineral oil, when used as a laxative, can interfere with the absorption of fat-soluble vitamins, including vitamin D.
• Calcium supplements should be monitored as high doses of vitamin D can lead to hypercalcemia.
• Steroids, such as prednisone, may increase the metabolism of vitamin D, requiring higher doses to maintain adequate levels.
• Aluminum-containing antacids may decrease the absorption of vitamin D, especially with long-term use.

Following are the food interactions for Cholecalciferol 2,000 IU drops:

• Avoid excessive consumption of foods rich in vitamin D like fatty fish (salmon, mackerel), egg yolks, and fortified dairy products. High vitamin D intake can lead to hypervitaminosis D.
• Maintain a balanced diet with adequate calcium and phosphorus as these minerals work synergistically with vitamin D for bone health.
• Avoid excessive intake of calcium supplements while on Cholecalciferol therapy to prevent potential mineral imbalances.
• Limit the intake of grapefruit and grapefruit juice as they may interfere with vitamin D metabolism, although the interaction is not well established.
• Avoid high-fiber foods close to taking the drops as fiber can reduce vitamin D absorption. Space out fiber-rich meals and the medication dose.
• Alcohol may impair vitamin D absorption and utilization. Minimize alcohol consumption for optimal vitamin D levels.
• Certain medications like orlistat and cholestyramine can reduce vitamin D absorption from the gut. Discuss with your healthcare provider if you're on such medications.

Cholecalciferol 2,000 IU Drops should be stored in a cool and dry place, preferably at room temperature (around 25°C/77°F). Protect the medication from excessive heat, direct sunlight, and moisture by keeping it in its original packaging or container. Ensure the bottle is tightly sealed after each use to maintain its potency and prevent contamination. It is crucial not to store the drops in the bathroom or kitchen, as these areas can have temperature fluctuations. Always check the expiry date on the packaging, and do not use the medication if it has expired. For disposal, do not pour the drops down the sink or flush them down the toilet. Consult your pharmacist or local waste disposal company for guidance on how to safely dispose of any unused or expired medication, ensuring it is kept out of the reach of children and pets.

Following are the quick tips for Cholecalciferol 2,000iu Drop:

• Take the drops as directed by your doctor or pharmacist.
• Administer the prescribed number of drops directly into your mouth or as advised by your healthcare provider.
• Cholecalciferol drops can be taken at any time of the day, but try to be consistent with the timing.
• You can take the drops directly or mix them with a small amount of food or beverage as directed.
• If using the dropper, ensure it is clean and avoid touching it to prevent contamination.
• Store the drops in a cool, dry place away from direct sunlight and moisture.
• Regularly monitor your vitamin D levels as advised by your healthcare provider.