Viocef (500mg) 12 Capsules

Ceftriaxone 500mg capsules work by inhibiting the synthesis of the bacterial cell wall. Ceftriaxone is a broad-spectrum cephalosporin antibiotic that specifically targets penicillin-binding proteins (PBPs) in susceptible bacteria. It binds to these PBPs, which are essential for cross-linking peptidoglycan strands in the bacterial cell wall during cell division. By inhibiting the activity of PBPs, ceftriaxone disrupts the formation of the cell wall, leading to cell lysis and bacterial death. This mechanism effectively weakens the structural integrity of the bacterial cell, resulting in a bactericidal effect.

Ceftriaxone 500mg

Ceftriaxone is a cephalosporin antibiotic.

Capsule

The following are the uses of Ceftriaxone 500mg Capsule:

• Used for treating severe bacterial infections like pneumonia, meningitis, and skin or abdominal infections.
• Used for surgical prophylaxis to prevent infections during and after surgery.
• Used for managing bone and joint infections, ensuring proper healing.
• Used in the treatment of sexually transmitted infections, particularly gonorrhea.
• Used for managing pelvic inflammatory disease, providing effective relief.
• Used for certain types of respiratory tract infections, offering quick recovery.
• Used as a reliable option for treating complicated urinary tract infections.
• Used for preventing infections in patients with weakened immune systems.

In the case of an overdose of Ceftriaxone 500mg Capsules, it is important to recognize the potential severity of this situation. Symptoms may include nausea, vomiting, diarrhea, and in more serious cases, seizures or kidney damage. If an overdose is suspected, seek medical advice promptly. Treatment options may include gastric lavage, supportive care, and monitoring of vital signs and kidney function. It is crucial to act quickly and ensure professional medical guidance to manage any potential complications.

In the case of a missed dose of Ceftriaxone 500mg Capsule, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting an alarm or using a medication reminder app to help you stay on track with your medication regimen. Consult your healthcare provider if you have any concerns or questions regarding missed doses.

To administer Ceftriaxone 500mg Capsule, gently pull the plunger to the prescribed dosage mark on the syringe, ensuring an accurate dose, and inject the medication intramuscularly, preferably into the upper outer quadrant of the buttock, following the instructions provided by your healthcare professional.

Here are the conditions or situations when Ceftriaxone 500mg Capsule should not be used:

• Avoid if you have a known allergy to Ceftriaxone or any other cephalosporin antibiotics.
• Do not use if you have a history of severe allergic reactions to penicillin.
• Contraindicated in patients with a history of jaundice or liver problems caused by Ceftriaxone.
• Should not be administered to newborns with hyperbilirubinemia or premature neonates.
• Not recommended for patients with a history of severe diarrhea caused by antibiotic use.
• Avoid if you have or have ever had colitis or other intestinal problems.
• Do not use if you have or may have phenylketonuria (PKU), as some brands of Ceftriaxone may contain phenylalanine.

The side effects of Ceftriaxone 500mg Capsule may include:

• Diarrhea
• Nausea and vomiting
• Abdominal pain or discomfort
• Skin rashes or itching
• Allergic reactions (hives, swelling, difficulty breathing)
• Increased liver enzymes
• Headache
• Dizziness

Following are the precautions and warnings for Ceftriaxone 500mg Capsule:

• Avoid use in patients with known hypersensitivity to ceftriaxone, other cephalosporins, or penicillins due to the risk of cross-reactivity.
• Use with caution in patients with a history of kidney or liver disease, as dosage adjustments may be required.
• Not recommended for neonates with hyperbilirubinemia, as ceftriaxone may displace bilirubin and increase the risk of kernicterus.
• May cause Clostridium difficile-associated diarrhea; discontinue use and seek medical attention if severe diarrhea occurs.
• Avoid concurrent use with calcium-containing IV solutions in neonates due to the risk of fatal precipitation.
• Patients with a history of gastrointestinal diseases, especially colitis, should use with caution, as antibiotics may exacerbate symptoms.
• Prolonged use may lead to the overgrowth of non-susceptible organisms, including fungi; monitor for secondary infections.
• May cause dizziness or fatigue; patients should exercise caution when driving or operating machinery.
• Use with caution in pregnant and breastfeeding women; consult a healthcare provider before use.
• If signs of an allergic reaction, such as rash, swelling, or difficulty breathing, occur, seek immediate medical attention.

Following are the drug interactions for Ceftriaxone 500mg Capsule:

• Concomitant use with calcium-containing solutions or products (e.g., calcium chloride, calcium gluconate) can lead to the formation of ceftriaxone-calcium precipitates, potentially causing fatal reactions.
• Avoid concurrent use with other neuromuscular blocking agents as it may prolong neuromuscular blockade.
• Ceftriaxone may decrease the effectiveness of oral contraceptives, requiring additional contraceptive measures.
• Probenecid can increase the blood levels of ceftriaxone, potentially increasing the risk of side effects.
• The risk of bleeding or bruising may increase when taken with anticoagulants like warfarin.
• Ceftriaxone may affect the metabolism of certain medications, including other antibiotics, leading to increased or decreased drug levels in the body.
• Concomitant use with loop diuretics (e.g., furosemide) may increase the risk of nephrotoxicity.

Following are the food interactions for Ceftriaxone 500mg Capsule:

• Avoid excessive alcohol consumption while taking Ceftriaxone, as it can increase the risk of liver-related side effects and may reduce the effectiveness of the medication.
• Grapefruit and grapefruit juice should be consumed with caution as they can affect the metabolism of Ceftriaxone, potentially increasing its levels in the body and the risk of side effects.
• Maintain adequate hydration and drink plenty of fluids to prevent dehydration, especially if experiencing diarrhea as a side effect.
• Avoid taking calcium-rich dairy products and antacids containing calcium, magnesium, or aluminum within 48 hours of taking Ceftriaxone, as they can reduce its absorption.
• High-fat meals may slightly delay the absorption of Ceftriaxone, but it is generally well-tolerated with food.
• Iron-rich foods or supplements may reduce the absorption of Ceftriaxone, so it is recommended to separate the intake of iron-containing products by at least 2 hours.
• Vitamin B deficiency may occur with prolonged use of Ceftriaxone, so consider including vitamin B-rich foods in your diet or consult your doctor about supplementation.
• Consult your healthcare provider for specific dietary recommendations based on your medical condition and treatment plan.

Ceftriaxone 500mg Capsules should be stored in a cool, dry area, specifically between 68°F and 77°F (20°C and 25°C), with excursions permitted between 59°F and 86°F (15°C and 30°C). It is crucial to keep the capsules in their original packaging, tightly sealed, to ensure their integrity and prevent exposure to moisture and light. Avoid storing them in the bathroom or kitchen, as these areas can have temperature fluctuations and humidity that may impact the medication's quality. Always check the expiration date on the packaging, and dispose of any unused or expired capsules responsibly. Do not flush them down the toilet or pour them into drains. Instead, contact your pharmacist or local waste management authorities for guidance on safe disposal practices to protect the environment. Keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Ceftriaxone 500mg Capsule:

• Take the capsule with a full glass of water to ensure proper swallowing.
• Ceftriaxone is typically taken once or twice daily as directed by your doctor.
• Swallow the capsule whole; do not crush, chew, or break it.
• It is best to take it at evenly spaced intervals to maintain an effective level in your body.
• Ceftriaxone can be taken with or without food, but taking it with food may reduce stomach upset.
• Store the capsules at room temperature, away from moisture and light.
• Inform your healthcare provider if you have a history of allergies, especially to penicillin or other antibiotics.