Vistamin (250mg) 10 Tablets

Penicillamine 250mg Tablet primarily exerts its therapeutic effects through its ability to bind with certain chemicals and heavy metals in the body. As a chelating agent, it forms stable complexes with substances like copper, lead, and other heavy metals, facilitating their elimination from the body. This chelation process helps to reduce the toxicity and harmful effects associated with excess metal accumulation. Additionally, penicillamine can inhibit the formation of abnormal cross-links between proteins, which is particularly relevant in conditions like Wilson's disease and rheumatoid arthritis, where abnormal protein structures contribute to disease progression. By interfering with these cross-links, penicillamine helps to alleviate symptoms and slow down disease processes.

Cheating Inhibitor

Tablet

The following are the uses of Penicillamine 250mg Tablet:

• Used for treating Wilson's disease, a condition where copper builds up in the body.
• Used to manage rheumatoid arthritis by reducing inflammation and slowing joint damage.
• Used for treating a rare kidney disorder called cystinuria, helping to prevent the formation of certain stones.
• Used in the treatment of lead poisoning to bind and eliminate lead from the body.
• Used for managing certain skin conditions like Pemphigus and Penfigoid, which cause painful blisters.
• Used to alleviate symptoms and slow the progression of systemic sclerosis, an autoimmune disease.
• Used as a second-line treatment for scleroderma, improving skin thickness and joint mobility.
• Used in specific cases of severe, persistent hives to reduce itching and inflammation.

In the case of an overdose of Penicillamine 250mg Tablets, the primary concern is the potential for severe gastrointestinal symptoms. Nausea, vomiting, and diarrhea may occur, and in severe cases, kidney damage or failure could result. It is essential to monitor renal function and seek medical advice promptly if an overdose is suspected. Treatment involves supportive care, including intravenous fluids and close observation to manage any adverse effects and prevent further complications.

In the case of a missed dose of Penicillamine 250mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss several doses, contact your healthcare provider for guidance on how to safely resume your medication without compromising its effectiveness.

To take Penicillamine 250mg Tablet, swallow the tablet whole with a full glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare provider.

Following are the conditions/situations when Penicillamine 250mg Tablet should not be taken:

• Avoid if you have a known allergy to Penicillamine or any other ingredients in the medication.
• Do not use if you have a history of blood disorders such as aplastic anemia or agranulocytosis.
• Contraindicated in individuals with a history of kidney disease or kidney dysfunction.
• Should not be taken if you have Wilson's disease, unless specifically prescribed for this condition.
• Not suitable for individuals with a history of lupus erythematosus.
• Avoid if you have a history of skin disorders or skin reactions to similar medications.
• Do not use if you have a condition called systemic sclerosis (scleroderma).
• Penicillamine should not be taken if you are breastfeeding, unless advised by a healthcare professional.

The side effects of Penicillamine 250mg Tablet may include:

• Skin rash or itching
• Nausea and vomiting
• Loss of appetite
• Metallic taste in the mouth
• Diarrhea
• Fatigue and weakness
• Joint pain
• Fever

Following are the precautions and warnings for Penicillamine 250mg Tablet:

• Not recommended for individuals with a history of allergic reactions to penicillamine or any other ingredients in the tablet.
• Regular blood and urine tests are necessary to monitor kidney and liver function during treatment.
• Patients with a history of kidney disease should exercise caution, as the drug may affect kidney function.
• Close monitoring is required for patients with a history of blood disorders, as it may cause a decrease in white blood cell count.
• Elderly patients may be more susceptible to side effects; dosage adjustments might be needed.
• This medication should be used with caution in patients with autoimmune diseases, as it may exacerbate symptoms.
• Patients should inform their doctor if they are pregnant, planning to become pregnant, or breastfeeding before taking this medication.

Following are the drug interactions for Penicillamine 250mg Tablet:

• Pyridoxine (vitamin B6) may reduce the effectiveness of Penicillamine, hence, co-administration should be avoided.
• Penicillamine can increase the effects of anticoagulants like Warfarin, leading to increased bleeding risk.
• It may decrease the absorption of Tetracycline antibiotics, thus reducing their effectiveness.
• When used with antacids containing aluminum, calcium, or magnesium, Penicillamine's absorption is reduced.
• Concomitant use with immunosuppressants like Cyclosporine may increase the risk of kidney toxicity.
• The effectiveness of Penicillamine can be reduced by Chloroquine, used for malaria treatment.
• Caution is advised with non-steroidal anti-inflammatory drugs (NSAIDs) as they may increase the risk of adverse effects.

Following are the food interactions for Penicillamine 250mg Tablet:

• Avoid excessive consumption of Vitamin C-rich foods like citrus fruits, tomatoes, and green vegetables as they can decrease the absorption of Penicillamine, reducing its effectiveness.
• Limit the intake of high-protein foods such as meat, fish, and dairy products, as Penicillamine may bind to proteins, leading to reduced absorption.
• Avoid drinking tea, coffee, or other caffeinated beverages with Penicillamine, as caffeine can interfere with the medication's action and increase the risk of side effects.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of Penicillamine, potentially altering its blood levels.
• Alcoholic beverages should be avoided or limited as they can increase the risk of liver-related side effects and may also reduce the effectiveness of the medication.
• Ensure a balanced diet with adequate hydration to support overall health during Penicillamine therapy.
• Consult a dietician or healthcare provider for personalized dietary advice, especially if you have specific dietary restrictions or health conditions.

Penicillamine 250mg Tablets should be stored in a cool, dry area away from direct sunlight and moisture. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent contamination. It is crucial to avoid exposing the medication to high temperatures or humidity, so refrain from storing it in bathrooms or near heat-emitting appliances. Always adhere to the expiration date printed on the packaging and dispose of any unused or expired tablets responsibly. To safely dispose of the medication, do not flush it or pour it down the drain; instead, consult a pharmacist or healthcare professional for appropriate disposal guidelines. Additionally, ensure that the medication is kept out of children's reach to prevent accidental consumption.

Following are the quick tips for Penicillamine 250mg Tablet:

• Consult your doctor for personalized dosage instructions based on your medical condition.
• Take the tablet with a full glass of water to aid absorption.
• Consume the tablet on an empty stomach, at least 1 hour before or 2 hours after meals.
• If stomach discomfort occurs, discuss taking the medication with food.
• Avoid consuming alcohol while on this medication to prevent potential interactions.
• Regularly monitor your health and report any unusual symptoms to your healthcare provider.
• Store the medication in a cool, dry place, away from direct sunlight and moisture.