Voben (0.5%) 5ml Eye Solution

Levobunolol HCl eye drops work by selectively blocking beta-adrenergic receptors in the eye. This mechanism of action reduces the production of aqueous humor, a fluid in the eye, by decreasing the rate of fluid secretion from the ciliary body. Beta-blockers like levobunolol primarily target the β1 and β2 adrenergic receptors, which are responsible for stimulating the production of aqueous humor. By blocking these receptors, levobunolol lowers intraocular pressure (IOP) and is primarily used to treat conditions like glaucoma and ocular hypertension. This reduction in IOP helps prevent damage to the optic nerve and improves eye health.

Beta-adrenergic blocking agent

Drop

The following are the uses of Levobunolol HCL Eye Drop:

• Used for treating glaucoma and ocular hypertension, reducing intraocular pressure.
• Used for preventing further optic nerve damage and vision loss.
• Used for managing elevated eye pressure, providing a sustained effect.
• Used for controlling fluid production in the eye, aiding drainage.
• Used for long-term management of open-angle glaucoma and ocular hypertension.
• Used for once or twice daily dosage, depending on individual needs.
• Used for as an adjunct therapy, often combined with other eye medications.

In the case of an overdose of Levobunolol HCL Eye Drops, symptoms may include extreme drowsiness, slow heart rate, difficulty breathing, and cold or clammy skin. If you or someone you know has ingested a large amount of this medication, it is important to seek medical advice promptly. Quick action can help prevent potential complications, especially in cases where the overdose is severe. Medical professionals can provide guidance and support to ensure the best possible outcome.

In the case of a missed dose of Levobunolol HCL Eye Drops, it is important to administer the medication as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. However, do not double the dose to make up for the missed one, as this may increase the risk of side effects. It is recommended to create a routine or set reminders to help you remember to take your eye drops consistently at the prescribed times.

To administer Levobunolol HCL Eye Drops, gently tilt your head back, pull the lower eyelid down to create a pocket, and hold the dropper close to the eye; release one drop into the pocket, blink gently, and keep your eyes closed for 1-2 minutes to allow the medication to absorb.

Following are the conditions when Levobunolol HCl Eye Drops should not be used:

• Should not be used if you have a known allergy or sensitivity to Levobunolol HCl or any other beta-blocker medications.
• Not suitable for individuals with respiratory diseases such as asthma, chronic bronchitis, or severe chronic obstructive pulmonary disease (COPD).
• Contraindicated in patients with a history of severe heart failure or a heart block.
• Should not be used if you have a slow heart rate (bradycardia) or low blood pressure (hypotension).
• Avoid using these eye drops if you have uncontrolled diabetes, as they can mask the symptoms of hypoglycemia.
• Not recommended for individuals with depression, as beta-blockers may worsen the symptoms.
• Do not use these eye drops if you have hyperthyroidism that is not adequately controlled.
• Contraindicated during breastfeeding, as Levobunolol HCl can pass into breast milk and may harm the nursing infant.

The side effects of Levobunolol HCL Eye Drops may include:

• Stinging, burning, or discomfort in the eye
• Temporary blurred vision
• Dry or itchy eyes
• Watery eyes
• Headache
• Dizziness
• Fatigue or weakness
• Increased sensitivity to light

Following are the precautions and warnings for Levobunolol HCL Eye Drops:

• Do not use if you are allergic to Levobunolol or any other ingredients in the eye drops.
• If you have a history of respiratory diseases like asthma or chronic obstructive pulmonary disease (COPD), use with caution as it may exacerbate these conditions.
• Patients with cardiovascular problems such as bradycardia, heart block, or heart failure should use it under medical supervision.
• May cause temporary blurred vision after administration. Avoid driving or operating machinery until your vision is clear.
• Contact lenses should be removed before instilling the eye drops and can be reinserted after 15 minutes.
• For pediatric use, consult a healthcare professional as the safety and efficacy may vary in children.
• Elderly patients may be more susceptible to the effects of Levobunolol; therefore, close monitoring is necessary.
• Always follow the prescribed dosage and consult a doctor if you have any concerns or experience any adverse effects.

Following are the drug interactions for Levobunolol HCl Eye Drops:

• Beta-blockers, Concomitant use with other beta-adrenergic blocking agents may result in additive effects and increased risk of adverse events, including cardiovascular effects like bradycardia and hypotension.
• Digoxin, Levobunolol can increase the plasma levels of digoxin, potentially leading to increased risk of digoxin toxicity.
• Insulin or oral hypoglycemic agents, Beta-blockers may mask the signs and symptoms of hypoglycemia and delay recovery from it.
• Anesthetics, Levobunolol may interact with anesthetics, potentially causing severe hypotension and cardiac depression during anesthesia.
• Anticholinesterase inhibitors, Concurrent use can antagonize the effects of both drugs on intraocular pressure.
• Clonidine, Abrupt withdrawal of clonidine after concurrent use with beta-blockers may lead to a severe increase in blood pressure.
• Verapamil, Concomitant use can lead to severe hypotension and cardiac failure.

Following are the food interactions to consider with Levobunolol HCl Eye Drops:

• Avoid consuming alcohol during the treatment period as it may temporarily impair your vision and increase the risk of side effects.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the absorption of Levobunolol, potentially leading to increased drug levels in the body.
• Caffeine-rich foods and beverages like coffee, tea, and chocolate might increase eye pressure, so it's advisable to limit their consumption.
• Salt and salty foods may need to be monitored, as Levobunolol can increase the sensitivity of the eyes to salt, affecting eye pressure.
• It is generally recommended to wait a few minutes after using eye drops before eating to prevent potential irritation or dilution of the medication.
• No significant interactions have been reported with specific foods, but maintaining a balanced diet is advisable for overall eye health.
• Always consult your healthcare provider or pharmacist for personalized advice regarding dietary restrictions or interactions based on your medical history.

Levobunolol HCL Eye Drops should be stored properly to maintain their effectiveness and safety. Keep the eye drops in a cool and dry place, preferably at room temperature, ensuring they are protected from direct sunlight and heat sources. The original container should be tightly sealed to prevent contamination and maintain the integrity of the medication. It is crucial not to store the eye drops in the bathroom due to humidity concerns. Always check the expiration date, and if the drops are past their prime, proper disposal is essential. Do not dispose of them by flushing or pouring them down the drain; instead, consult a pharmacist or healthcare professional for appropriate disposal methods. Keep the eye drops out of children's reach to prevent accidental exposure.

Following are the quick tips for Levobunolol HCL Eye Drops:

• Wash your hands thoroughly before administering the eye drops to maintain hygiene.
• Tilt your head back, gently pull down your lower eyelid, and instill the prescribed number of drops into the eye.
• Avoid touching the dropper tip with your hands or eyes to prevent contamination.
• Close your eyes gently after instilling the drops and apply light pressure to the inner corner of the eye for better absorption.
• If you use other eye medications, wait at least 5-10 minutes before applying the next one to prevent washout.
• Store the eye drops at room temperature, away from direct sunlight and moisture.
• Do not share your eye drops with others to prevent the spread of infection.
• Inform your doctor if you have any eye surgery or develop any eye discomfort during treatment.