Voltex Gel 20g

Diclofenac gel works by inhibiting the cyclooxygenase (COX) enzymes, primarily COX-2, which are responsible for the production of prostaglandins. Prostaglandins are involved in mediating pain, inflammation, and fever responses in the body. When applied topically, diclofenac penetrates the skin and reaches the site of inflammation. It selectively blocks the COX-2 enzyme, reducing the formation of prostaglandins in the affected area. By inhibiting the production of these inflammatory mediators, diclofenac gel helps to alleviate pain, decrease swelling, and improve joint mobility in the targeted region without significantly affecting the systemic circulation, thus minimizing the potential for systemic side effects.

Diclofenac

Nonsteroidal anti-inflammatory drug (NSAID).

Gel

The following are the uses of Diclofenac Gel:

• Used for relieving pain and reducing inflammation in conditions like osteoarthritis, rheumatoid arthritis, and other joint or muscle injuries.
• Used for managing acute pain, such as post-surgical pain or pain due to strains and sprains.
• Used for treating localized pain in specific areas like the knees, elbows, or back.
• Used for reducing swelling and discomfort in soft tissue injuries.
• Used for providing targeted pain relief without the systemic side effects of oral medications.
• Used for easing pain and stiffness in affected joints, improving mobility.
• Used for managing pain and inflammation in conditions like tendinitis and bursitis.
• Used for offering a non-invasive alternative to oral or injectable pain medications.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• For pain and swelling, apply the gel to the affected area 2-3 times a day.
• For muscle pain and sprains, initially apply 2 inches (5cm) gel to the affected area and rub in gently until it is absorbed into the skin, repeating this 3-4 times a day.
• For osteoarthritis, apply 2 inches (5cm) of gel to the affected area and rub in gently until it is absorbed into the skin, repeating this 3-4 times per day, with a maximum of 16g per day per adult.
• For migraine, follow the instructions that come with the medication as the dose will depend on the type of migraine medication you take. For example, if you are using a diclofenac nasal spray, you should spray once into each nostril. If you are using a dermal patch, you should apply the patch to the skin and keep it in place for up to 10 hours.
• For diabetic neuropathy, apply the gel topically to the affected area as directed by a doctor.
• For eye inflammation, dilute the diclofenac and apply it to the skin adjacent to the inner corner of the eye, nearest to the bridge of the nose, preferably with a half drop on the tip of a clean finger to massage into the skin. Do not apply directly to the eyes.
• Always follow the specific dosage instructions provided with your medication. If you have any questions or concerns, consult your doctor.

In the case of an overdose of Diclofenac Gel, it is important to take prompt action. Remove any remaining gel from the skin and wash the affected area thoroughly with soap and water. Seek medical advice immediately, and inform the healthcare professional about the amount of gel applied and the time since application. They will provide guidance and monitor for any potential adverse effects, ensuring appropriate treatment if needed. Quick response and consultation with a medical expert are key in managing Diclofenac Gel overdoses effectively.

In the case of a missed dose of Diclofenac Gel, it is important to apply the gel as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for advice, as they may recommend adjusting your dosage to ensure you receive the proper amount of medication. It is best to apply the gel at around the same time each day to maintain consistent pain relief.

To apply Diclofenac Gel, clean and dry the affected area, then gently squeeze the gel from the tube and apply a thin layer, massaging it into the skin until it is absorbed, following the dosage instructions provided by your healthcare provider.

Here are the conditions and situations when Diclofenac Gel should not be used:

• Do not use if you have a known allergy or hypersensitivity to Diclofenac, aspirin, or other non-steroidal anti-inflammatory drugs (NSAIDs).
• Avoid using the gel if you have a history of asthma or severe allergic reactions triggered by NSAIDs.
• Not recommended for individuals with active gastrointestinal bleeding or perforation.
• Should not be applied to open wounds, infections, or areas of skin that are inflamed or damaged.
• Contraindicated in individuals with severe heart failure or heart disease.
• Do not use if you have a history of stroke, mini-stroke (TIA), or blood clots.
• Not suitable for patients with severe kidney or liver impairment.
• Avoid using the gel during the last three months of pregnancy and while breastfeeding.
• Should not be used on children under the age of 16 years.
• Do not use the gel if you have a history of stomach or intestinal ulcers.

The side effects of Diclofenac Gel may include:

• Skin redness or irritation at the application site
• Itching or rash
• Dry skin
• Swelling or bruising
• Burning or stinging sensation
• Allergic reactions (skin hives, difficulty breathing, swelling of the face/lips/tongue)
• Increased sensitivity to sunlight
• Headache

Following are the precautions and warnings for Diclofenac Gel:

• Avoid contact with eyes, nose, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water.
• Do not apply the gel to open wounds, infections, or inflamed skin conditions.
• Wash your hands thoroughly after applying the gel to avoid accidental transfer to sensitive areas.
• Diclofenac gel is for external use only. Do not ingest or apply to large areas of the body.
• Avoid using the gel on broken or damaged skin, as it may increase the risk of systemic absorption.
• Patients with a history of asthma, allergies, or aspirin sensitivity should use the gel with caution, as it may trigger respiratory reactions.
• Consult a doctor if you are pregnant, planning to become pregnant, or breastfeeding before using Diclofenac Gel.

Following are the drug interactions for Diclofenac Gel:

• Concurrent use with other non-steroidal anti-inflammatory drugs (NSAIDs) may increase the risk of gastrointestinal bleeding and kidney problems.
• Diclofenac can interact with anticoagulants (e.g., warfarin, heparin) and antiplatelet drugs (e.g., clopidogrel), enhancing the risk of bleeding.
• The gel may increase the plasma levels of lithium and digoxin, potentially leading to toxicity.
• When combined with diuretics, it can reduce their natriuretic effect and increase the risk of renal toxicity.
• Using diclofenac with angiotensin-converting enzyme (ACE) inhibitors or angiotensin II receptor blockers (ARBs) may decrease their antihypertensive effect.
• Caution is advised with concomitant use of methotrexate, as diclofenac may increase its plasma concentration and toxicity.
• It may also reduce the effectiveness of certain antihypertensive medications, such as beta-blockers and dihydropyridine calcium channel blockers.

Following are the food interactions for Diclofenac Gel:

• Avoid excessive alcohol consumption while using Diclofenac Gel as it may increase the risk of gastrointestinal bleeding and liver damage.
• Grapefruit and grapefruit juice should be consumed with caution as they can affect the metabolism of Diclofenac, potentially increasing its levels in the body and the risk of side effects.
• Limit the intake of fatty or greasy foods, as Diclofenac Gel is meant for topical application and oral consumption of high-fat meals may affect the overall medication regimen.
• Avoid spicy foods if the Diclofenac Gel is applied to sensitive areas, as it may cause a burning sensation or irritation.
• Caffeinated beverages should be consumed in moderation as caffeine may slightly reduce the absorption of Diclofenac through the skin.
• Avoid eating foods rich in vitamin K (like leafy greens) in excess, as Diclofenac can interfere with blood clotting and high vitamin K intake might reduce the medication's effectiveness.
• There is no specific food restriction for Diclofenac Gel, but maintaining a healthy diet supports overall well-being during treatment.
• Always follow the healthcare provider's instructions regarding the application of Diclofenac Gel and dietary considerations.

Diclofenac Gel should be stored in a cool and dry place, preferably at room temperature, ensuring it is kept away from direct sunlight, heat, and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial to pay attention to the expiration date on the packaging, and any unused or expired gel should be disposed of responsibly. Avoid flushing or pouring it down the drain; instead, consult a pharmacist or healthcare professional for guidance on proper disposal methods. Keep the gel out of children's reach to prevent accidental exposure, as it is meant for external use only. Always handle and store medications with care to maintain their effectiveness and safety.

Following are the quick tips for Diclofenac Gel:

• Wash your hands before and after applying the gel to maintain hygiene.
• Clean and dry the affected area before gel application.
• Apply a thin layer of gel to the skin and gently rub it in until absorbed.
• Avoid covering the treated area with bandages or clothing immediately after application.
• Do not apply the gel on broken or irritated skin.
• Avoid contact with eyes, nose, and mouth when using the gel.
• Store the gel at room temperature, away from direct sunlight and moisture.

It is crucial to monitor your health while taking Diclofenac Diethylamine 1% to ensure that the medication is working safely and effectively. To that end, your doctor may require you to undergo certain lab tests to check for changes and ensure that you remain in good health. These tests typically include a Blood Chemistry Profile, Liver Function Tests, Kidney Function Tests, Hemoglobin Concentration, White Blood Cell Count, and often Electrolyte Panels. The Blood Chemistry Profile assesses essential biomarkers in your blood like potassium, sodium, calcium, phosphorus, and chloride, ensuring that these levels are normal and your body's chemical balance is maintained while on the drug. Liver Function Tests assess the organ's function through liver enzyme levels (such as alanine aminotransferase (ALT) and aspartate aminotransferase (AST)) and bilirubin, which indicates liver health. These tests are crucial as Diclofenac can put stress on the liver, and cautions against any undue harm to this vital organ. Kidney Function Tests evaluate kidney function by measuring blood levels of creatinine and blood urea nitrogen (BUN). Since Diclofenac can be processed by the kidneys, these tests are important to monitor medication processing and eliminate it from the body. Hemoglobin Concentration tests monitor if enough oxygen reaches your organs and tissues and whether it indicates anemia, a condition that long-term use of nonsteroidal anti-inflammatory drugs like diclofenac can exacerbate. White Blood Cell Count measures the number of white blood cells, vital to your immune system. This test helps spot any signs of an immune disorder or infection. Electrolyte Panels evaluate levels of sodium and other electrolytes, maintaining nerve and muscle function and ensuring proper fluid balance in the body. These lab tests serve as a monitoring tool for your health care provider, aiding in the early detection of potential drug side effects or