Voltrel Gel 20gm 1's

Diclofenac diethylamine gel is a topical nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the cyclooxygenase (COX) enzymes, mainly COX-2. When applied to the skin, diclofenac penetrates the underlying tissues and reduces inflammation by blocking the production of prostaglandins, which are key mediators of pain and inflammation. This mechanism of action helps to alleviate pain and inflammation associated with various musculoskeletal conditions, such as arthritis and sprains, by directly targeting the affected area without significant systemic absorption.

Diclofenac diethylamine

Non-steroidal anti-inflammatory drug (NSAID)

Gel

The following are the uses of Diclofenac diethylamine Gel:

• Used for relieving pain and reducing inflammation in muscles and joints, such as strains, sprains, and arthritis.
• Used for managing post-traumatic pain and swelling, aiding in the healing process.
• Used for treating acute pain and swelling after minor surgical procedures.
• Used for easing pain and stiffness in conditions like tendonitis and bursitis.
• Used for providing targeted pain relief in localized areas, offering a convenient application method.
• Used for reducing pain and inflammation in soft tissue injuries, promoting faster recovery.
• Used for managing chronic pain conditions, offering long-lasting relief when applied regularly.
• Used for alleviating symptoms of acute gout attacks, reducing pain and inflammation.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• For pain and swelling, apply the gel to the affected area 2-3 times a day.
• For muscle pain and sprains, initially apply 2 inches (5cm) gel to the affected area and rub in gently until it is absorbed into the skin, repeating this 3-4 times a day.
• For osteoarthritis, apply 2 inches (5cm) of gel to the affected area and rub in gently until it is absorbed into the skin, repeating this 3-4 times per day, with a maximum of 16g per day per adult.
• For migraine, follow the instructions that come with the medication as the dose will depend on the type of migraine medication you take. For example, if you are using a diclofenac nasal spray, you should spray once into each nostril. If you are using a dermal patch, you should apply the patch to the skin and keep it in place for up to 10 hours.
• For diabetic neuropathy, apply the gel topically to the affected area as directed by a doctor.
• For eye inflammation, dilute the diclofenac and apply it to the skin adjacent to the inner corner of the eye, nearest to the bridge of the nose, preferably with a half drop on the tip of a clean finger to massage into the skin. Do not apply directly to the eyes.
• Always follow the specific dosage instructions provided with your medication. If you have any questions or concerns, consult your doctor.

In the case of an overdose of Diclofenac diethylamine Gel, individuals may experience severe skin reactions at the application site, including redness, itching, and blistering. Systemic symptoms such as gastrointestinal distress, dizziness, and headaches can also occur. Promptly seek medical advice if an overdose is suspected, as healthcare professionals can provide guidance on managing symptoms and preventing potential complications. Timely intervention is essential to ensure appropriate treatment and minimize the risk of adverse effects.

In the case of a missed dose of Diclofenac diethylamine Gel, it is recommended to apply the gel as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra gel to make up for the missed dose, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare provider for guidance on how to resume your treatment safely.

To apply Diclofenac diethylamine Gel, clean and dry the affected area, then gently massage a small amount of the gel onto the skin, covering the entire painful or swollen area, usually 2 to 4 times a day or as directed by your doctor.

Here are the situations when Diclofenac diethylamine Gel should not be used:

• Avoid using if you have a known allergy or sensitivity to Diclofenac or any other NSAID (Non-Steroidal Anti-Inflammatory Drugs) ingredients.
• Do not apply on or near open wounds, infections, or skin conditions like eczema, dermatitis, or untreated burns.
• Contraindicated in individuals with a history of asthma or severe allergic reactions triggered by aspirin or other NSAIDs.
• Should not be used in people with severe heart failure or heart disease.
• Avoid using on areas where you have skin conditions such as psoriasis or it could make these conditions worse.
• Not recommended for individuals with a history of gastrointestinal bleeding or perforation.
• Do not use if you are in the third trimester of pregnancy or breastfeeding.
• Diclofenac gel is not suitable for children and adolescents under 18 years of age.
• Do not use on more than two body areas at the same time.

The side effects of Diclofenac Diethylamine Gel may include:

• Skin irritation at the application site, such as redness, itching, or rash.
• Burning or stinging sensation on the skin.
• Dryness or peeling of the skin.
• Allergic reactions, including hives, swelling, or difficulty breathing.
• Headache or dizziness.
• Nausea or stomach discomfort.
• Increased sensitivity to sunlight (photosensitivity).
• Skin discoloration or bruising at the application area.

Following are the precautions and warnings for Diclofenac Diethylamine Gel:

• Avoid contact with eyes, nose, mouth, and other mucous membranes. In case of accidental contact, rinse thoroughly with water.
• Wash your hands thoroughly after applying the gel to avoid accidental transfer to sensitive areas.
• Do not apply the gel to open wounds, infections, or areas of skin that are inflamed or irritated.
• Diclofenac gel is for external use only. Do not swallow or ingest it.
• If you are pregnant or breastfeeding, consult your doctor before using this medication.
• Avoid using the gel on large areas of skin or under occlusive dressings, as this may increase the risk of side effects.
• Discontinue use and seek medical attention if you experience any skin reactions, such as rash, itching, or severe burning.
• Keep out of reach of children and pets. Store in a cool, dry place, away from direct sunlight.

Following are the drug interactions for Diclofenac diethylamine Gel:

• If used with other NSAIDs (e.g., ibuprofen, naproxen), there is an increased risk of gastrointestinal bleeding and kidney problems.
• It may reduce the blood pressure-lowering effect of ACE inhibitors and angiotensin receptor blockers.
• The diuretic effect of loop diuretics can be reduced by Diclofenac.
• Combining with corticosteroids may increase the risk of gastrointestinal bleeding and delay wound healing.
• Lithium levels can be increased, leading to potential lithium toxicity.
• Blood pressure medications like beta-blockers and diuretics may have reduced effectiveness when used with Diclofenac.
• Anticoagulants (e.g., warfarin) may have their effects enhanced, increasing the risk of bleeding.

Following are the food interactions for Diclofenac diethylamine Gel:

• Avoid excessive alcohol consumption while using this medication, as alcohol can increase the risk of gastrointestinal bleeding and liver toxicity.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of Diclofenac, potentially increasing its levels in the body and the risk of side effects.
• Avoid fatty or greasy foods, as Diclofenac diethylamine gel is primarily for topical use and should not be applied to areas with significant amounts of fat.
• The gel should not be applied to skin that is broken or has open wounds, and it should be kept away from the eyes, nose, and mouth to avoid accidental ingestion.
• Avoid using the gel on skin areas where you plan to apply other topical medications or treatments to prevent potential interactions.
• There is no significant interaction with specific foods, but maintaining a balanced diet is essential for overall health while using any medication.
• Consult your healthcare provider if you have dietary restrictions or concerns regarding food interactions with Diclofenac diethylamine gel.

Diclofenac diethylamine gel should be stored in a cool and dry place, preferably at room temperature, ensuring protection from direct sunlight and moisture. The gel tube should be tightly sealed after each use to maintain its integrity and effectiveness. It is crucial not to freeze the gel and to keep it away from heat sources, as temperature fluctuations can impact its quality. Always check the expiration date, and if the gel has expired or is no longer needed, proper disposal is essential. Do not pour it down the drain or discard it with regular household waste; instead, follow local guidelines for pharmaceutical waste disposal or consult a healthcare professional for guidance on safe disposal methods. Keep the gel out of children's reach to prevent accidental exposure.

Following are the quick tips for Diclofenac diethylamine Gel:

• Wash your hands before and after applying the gel for hygiene and to avoid irritation.
• Apply a thin layer of gel to the affected area and gently rub it in until absorbed.
• Use only the prescribed amount; more gel doesn't mean faster relief.
• Avoid covering the treated area with tight clothing or bandages to allow proper ventilation.
• Do not apply the gel to broken or irritated skin. Seek medical advice if needed.
• Consult your healthcare provider if you experience skin reactions or if symptoms persist.
• Store the gel at room temperature, away from direct sunlight and moisture.

It is crucial to monitor your health while taking Diclofenac Diethylamine 1% to ensure that the medication is working safely and effectively. To that end, your doctor may require you to undergo certain lab tests to check for changes and ensure that you remain in good health. These tests typically include a Blood Chemistry Profile, Liver Function Tests, Kidney Function Tests, Hemoglobin Concentration, White Blood Cell Count, and often Electrolyte Panels. The Blood Chemistry Profile assesses essential biomarkers in your blood like potassium, sodium, calcium, phosphorus, and chloride, ensuring that these levels are normal and your body's chemical balance is maintained while on the drug. Liver Function Tests assess the organ's function through liver enzyme levels (such as alanine aminotransferase (ALT) and aspartate aminotransferase (AST)) and bilirubin, which indicates liver health. These tests are crucial as Diclofenac can put stress on the liver, and cautions against any undue harm to this vital organ. Kidney Function Tests evaluate kidney function by measuring blood levels of creatinine and blood urea nitrogen (BUN). Since Diclofenac can be processed by the kidneys, these tests are important to monitor medication processing and eliminate it from the body. Hemoglobin Concentration tests monitor if enough oxygen reaches your organs and tissues and whether it indicates anemia, a condition that long-term use of nonsteroidal anti-inflammatory drugs like diclofenac can exacerbate. White Blood Cell Count measures the number of white blood cells, vital to your immune system. This test helps spot any signs of an immune disorder or infection. Electrolyte Panels evaluate levels of sodium and other electrolytes, maintaining nerve and muscle function and ensuring proper fluid balance in the body. These lab tests serve as a monitoring tool for your health care provider, aiding in the early detection of potential drug side effects or