Vonnp (20mg) 30 Tablets

Vonnp (20mg) 30 Tablets

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  • Manufacturer Horizon Pharmaceuticals (Pvt.) Ltd.
  • Generic Name Vonoprazan

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Description

    Vonoprazan is a novel potassium-competitive acid blocker (P-KAB) or proton pump inhibitor (PPI) that has been recently approved for the treatment of gastric acid-related disorders such as gastroesophageal reflux disease (GERD), stomach ulcers, and Zollinger-Ellison syndrome. Unlike some of its predecessors, vonoprazan is more selective in its action. This selectivity allows vonoprazan to block more proton pumps in the gastric parietal cells, resulting in potent acid suppression. This strong acid suppression, coupled with a quicker onset of action, makes vonoprazan a more effective and efficient treatment option for patients suffering from gastric acid disorders. Upon taking vonoprazan, it works by blocking the proton pump enzyme system (the "proton pump") in the wall of the stomach, which produces hydrochloric acid. By inhibiting the proton pump, vonoprazan reduces the production of stomach acid. This helps to relieve the symptoms of GERD and allows for the healing of any damage to the esophagus or stomach caused by excess acid. Vonoprazan generally is well-tolerated by patients with mild and transient side effects. Common side effects may include diarrhea, nausea, constipation, and headaches. It's also important to note that, like all PPIs, vonoprazan may interact with other medications. Thus, it is important to always consult with a healthcare provider before starting any new medication. Overall, vonoprazan is a powerful and effective acid-suppressing medication that offers a new option for the treatment of GERD and other gastric acid disorders.

  • Ingredients

    Vonoprazan
  • Drug Class

    Potassium-Competitive Acid Blockers (Pcab)

  • Dosage Form

    Tablet
  • Uses

    Unveiling its multifaceted uses and transformative applications as follows:

    • Treats heartburn caused by gastroesophageal reflux disease• GERD.
    • Helps relieve heartburn caused by acid reflux.
    • First line of treatment for heartburn on expiry of trial of proton pump inhibitors (PPIs).
    • Can be used in short-term (4 weeks) for erosion of the lining of the esophagus (erosive esophagitis).
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • For heartburn and acid reflux- Take 1 tablet once daily for up to 14 days.
    • For erosive esophagitis- Take 1 tablet once or twice daily for up to 8 weeks.
    • For maintenance of healed erosive esophagitis- Take 1 tablet once or twice daily.
  • In case of Overdose

    An overdose of Vonoprazan can lead to severe symptoms such as nausea, vomiting, diarrhea, and abdominal pain. It is crucial to seek immediate medical attention if you experience any of these symptoms due to an overdose of this medication. Medical professionals will actively address these symptoms and support vital functions to prevent further health complications. In severe cases of overdose, a patient may be induced into a coma and required decompression technique, which involves the insertion of a tube through the mouth to assist in breathing and maintaining a stable heartbeat.

  • Missed Dose

    It is crucial to adhere to the prescribed dosage of vonoprazan 20mg. If you miss a dose, you can take it as soon as you remember, unless it is almost time for your next scheduled dose. In this case, it is best to skip the missed dose and resume your regular dosage schedule. It is not recommended to double up on doses to make up for a missed one. If you have any concerns or questions about missing a dose, it is important to consult a doctor for further guidance. They can provide you with instructions and peace of mind regarding your medication.

  • How To Use

    Before starting Vonoprazan, it is crucial to read the medication guide provided by the pharmacist, which will explain how to use the drug properly and potential side effects to be aware of. Take note, Vonoprazan is to be taken orally, typically once every day with or without food, at the same time every day to maintain a consistent level of the medicine in your blood. For the best results, it is important to follow medical instructions and take the medication as directed by your doctor. Most people feel better within four weeks, but it may take up to eight weeks to feel the full benefit of this medication. If you are not feeling better after eight weeks, contact your doctor. The dosage is based on your medical condition and your response to treatment, and your doctor may start you on a low dose and gradually increase it to minimize the risk of side effects. To get the most benefit from taking Vonoprazan, it is important to take it regularly. Do not stop taking this medication without discussing it with your doctor first. Suddenly stopping taking this medication may cause acid rebound, which refers to an increase in acid production in the stomach and can result in serious acidity and heartburn symptoms returning. Remember, it is important to always consult a healthcare professional if you have any questions or concerns about taking Vonoprazan 20mg.

  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • Hypersensitivity or allergies
    • Severe kidney problems
    • Ulcers with bleeding
    • Lack of vitamin B12 absorption
    • Pregnancy and breastfeeding
  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Nausea
    • Heartburn
    • Vomiting
    • Constipation
    • Dry mouth
    • Vaginal itching
    • Headaches
  • Precautions & Warnings

    The warnings and precautions for Vonoprazan are:

    • May mask symptoms of gastric malignancy
    • Renal and hepatic impairment
    • Pregnancy
  • Drug Interactions

    The drug interactions with vonoprazan include:

    • CYP3A4 Inhibitors (e.g., ketoconazole) – Can increase vonoprazan levels.
    • CYP3A4 Inducers (e.g., rifampin) – Can decrease vonoprazan levels.
  • Food Interactions

    For Vonoprazan, food interactions that should be considered are:

    • Taking before meals may enhance absorption.
  • Storage/Disposal

    Vonoprazan is a medication that should be stored at room temperature in an airtight container. It is important to remember that it should be kept dry and away from moisture, so it is not recommended to store Vonoprazan in the bathroom or near a sink due to high humidity, which can negatively impact the medication. For safekeeping, it is also important to keep Vonoprazan out of reach of children and pets at all times to prevent accidental consumption. If you have any questions or concerns about storing Vonoprazan, consult your physician, pharmacist, or local healthcare provider for further guidance.

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