Vorneu (5mg) 14 Tablets

Vorneu (5mg) 14 Tablets

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  • Manufacturer Hilton Pharma (Pvt.) Ltd.
  • Generic Name Vortioxetine

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Description

    Vortioxetine is a novel antidepressant prescribed for major depressive disorder (MDD) that works by acting on the brain's serotonin system, a key pathway involved in regulating emotions and mood. Serotonin is a neurotransmitter, a chemical that nerve cells use to communicate with each other. It plays a crucial role in maintaining emotional balance and supporting various cognitive processes. Vortioxetine enhances the activity of serotonin within neurons by stimulating its release and inhibiting its reuptake. By these selective actions, serotonin's effects are amplified, leading to an alleviation of depressive symptoms. Vortioxetine also interacts with other neurotransmitter systems in the brain, including dopamine and norepinephrine, though its precise role in antidepressant action is not fully understood. The drug has been shown to have some affinity for histamine and melatonin receptors as well. By enhancing serotonin activity and regulating neurotransmission, vortioxetine helps to alleviate the symptoms of MDD.

  • Ingredients

    Vortioxetine
  • Drug Class

    Depression (Major Depressive Disorder) • Serotonin Reuptake Inhibitor (Ssri)

  • Dosage Form

    Tablet
  • Uses

    Unveiling its multifaceted uses and transformative applications as follows:

    • Treat depression, anxiety, and other mental health conditions.
    • Help improve energy levels and feelings of exhaustion.
    • Help regain interest in pleasurable activities.
    • Improve focus and reduce unwanted distracting thoughts/surfing.
    • Reduce feelings of guilt or worthlessness.
    • Reduce thoughts of suicide or self-harm.
    • Enhance emotional well-being.
    • Ease tension and anxiety.
    • Evoke feelings of relaxation and optimism.
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • For the treatment of major depressive disorder (MDD) or depressive episodes associated with bipolar disorder (BD)- Initially, 10 mg once daily for 1 week, followed by 20 mg once daily.
    • The maximum dose is 20 mg once daily; increasing the dose above 20 mg does not appear to confer additional clinical benefits.
    • Vortioxetine should be taken consistently, preferably at the same time each day, with or without food.
  • In case of Overdose

    An overdose of vortioxetine may be a medical emergency that requires careful monitoring and supportive care. Vital signs need to be monitored, and oxygen supplementation may be provided if necessary along with gastrointestinal decontamination if required. Severe cases may result in a gastric lavage to flush the stomach of excess medication. It is also necessary to monitor cardiac and pulmonary function and provide nutritional support where needed. Psychological distress needs to be monitored and managed through clinical monitoring and intervention. Further medical intervention may be given to address any complications.

  • Missed Dose

    Maintaining a regular schedule for taking vortioxetine is important because it helps ensure the medication's effectiveness. If you happen to forget a dose, take it as soon as possible, except if it is almost time for your next scheduled dose. In this case, you should skip the missed dose and continue with your regular dosage schedule. Doubling up on doses to make up for missed medicine can lead to an increased risk of side effects. If you frequently forget to take your medication or worry you often miss doses, speaking to your doctor or pharmacist would be wise. They could provide you with advice or suggestions to help you remember your medication or adjust your dosage or schedule based on your circumstances. It's vital to follow the treatment plan agreed upon with your healthcare team to achieve the best benefits of the medication.

  • How To Use

    Vortioxetine 5mg is a medication intended for adults. It should be consumed with food to enhance drug absorption. It is recommended to take this medication at a consistent time each day, ideally in the morning, to avoid potential disturbances in sleep patterns. A full treatment course lasting several weeks is typically recommended as it takes time to reach optimal effectiveness. Stopping this medication abruptly should be avoided to prevent withdrawal-like symptoms. If any difficulties arise in following the regimen or if issues such as appetite loss, agitation, or constipation, it is important to consult a medical professional, as they can offer suggestions and alternatives. Changing the dosage of this medication without consulting a medical professional can lead to unwanted health outcomes, therefore it is important to not do so. These steps serve as a general guide, and it is vital to consult a physician for specific directions to ensure the best outcome and avoidance of health risks.

  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • You are allergic to vortioxetine or any of the ingredients in the medication.
    • You have taken methylene blue injection within the last 14 days.
    • You have taken a monoamine oxidase inhibitor (MAOI) within the last 14 days (including Strengtedine, Phenelzine, and Tranylcypromine).
  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Dizziness
    • Dry mouth
    • Fatigue
    • Increased blood pressure
  • Precautions & Warnings

    The warnings and precautions for Vortioxetine are:

    • Patients with a history of suicide-related events or pre-existing suicidal ideation
    • Family history of bipolar disorder, mania, or hypomania
    • Seizure disorders or unstable epilepsy
    • Bleeding disorders, cirrhosis, narrow-angle glaucoma (without undergoing iridectomy)
    • Elderly patients
    • Pregnancy and lactation
    • CYP2D6 poor metabolizers
    • Patients taking strong CYP2D6 inhibitors or strong CYP450 inducers
  • Drug Interactions

    The drug interactions with vortioxetine include:

    • MAO Inhibitors (e.g., phenelzine) – Can cause serotonin syndrome.
    • Other SSRIs (e.g., fluoxetine) – Can increase risk of serotonin syndrome.
  • Food Interactions

    For Vortioxetine, food interactions that should be considered are:

    • Taking with food may help enhance absorption.
    • Avoid alcohol as it may increase the risk of side effects.
  • Storage/Disposal

    Vortioxetine is a type of antidepressant, and similar to other medications, it must be stored properly to ensure its effectiveness and safety. It should be stored at room temperature, ideally at 77°F (25°C). This medication should be kept in a dry place, away from direct heat and light. Be sure to keep the medication bottle closed when not in use. The bathroom is not a suitable place to store vortioxetine because of the high humidity levels, which can cause the tablets to degrade. For safety reasons, keep this medication out of children's and pets' reach at all times. Dispose of any unused or expired doses according to the instructions of your healthcare provider or pharmacist. It is important to always adhere to the storage instructions provided by the doctor, pharmacist, or medication label. If you have any questions or concerns about how to properly store vortioxetine, don't hesitate to ask your healthcare provider for guidance.

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