X PLENDED EZ 10/10MG TAB 10S

X PLENDED EZ 10/10MG TAB 10S

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  • Generic Name

    Ezetimibe 10mg, Rosuvastatin 10mg

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Storage/Disposal
  • Description

    Rosuvastatin 20mg is a medication that works to reduce cholesterol levels in the blood. It does this by blocking an enzyme called HMG-CoA reductase, which plays a key role in producing cholesterol in the body. By blocking this enzyme, rosuvastatin effectively reduces the body's natural cholesterol production and induces the absorption of LDL cholesterol, leading to lower overall cholesterol levels and reducing the risk of cardiovascular events such as heart attacks and strokes. Ezetimibe 10mg is another cholesterol-lowering medication with a different mechanism of action than rosuvastatin. Ezetimibe specifically blocks the absorption of cholesterol from the intestine into the bloodstream. It acts on the intestinal absorptive cells in the small intestine, where it binds to a receptor called the Niemann-Pick C1-like 1 (NPC1L1) receptor, thereby blocking the absorption of cholesterol from dietary sources. This leads to a reduction in overall cholesterol levels in the body. When used together, rosuvastatin 20mg and ezetimibe 10mg provide a complementary and synergistic approach to cholesterol management. Not only do they reduce endogenous cholesterol production and induce its breakdown (as mediated by rosuvastatin), but they also inhibit the absorption of cholesterol from dietary sources (mediated by ezetimibe). This dual mechanism of action leads to a robust reduction in LDL cholesterol levels in the blood, thereby lowering the risk of cardiovascular events such as heart attacks and strokes.

  • Ingredients

    Ezetimibe 10mg, Rosuvastatin 10mg

  • Drug Class

    Hmg-Coa Reductase Inhibitors (Statins):

  • Dosage Form

    Tablet

  • Uses

    Ezetimibe, Rosuvastatin combination is utilized for the following therapeutic indications:

    • Reduction of LDL cholesterol levels
    • Treatment of primary hyperlipidemia
    • Management of dyslipidemia
    • Cardiovascular risk reduction
    • Used in patients requiring additional cholesterol-lowering therapy beyond monotherapy with statins
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Cholesterol Level- Take 2 grams per day with dinner for cholesterol level less than 200.
    • Weight Loss- Take 5 grams with breakfast, lunch, dinner and bedtime for weight loss.
    • Diabetes- Take 5 grams with each meal to reduce hemoglobin A1C levels.
    • Hyperlipidemia- Take 20 mg of Rosuvastatin and 10 mg of Ezetimibe with dinner to reduce cholesterol levels.
  • In case of Overdose

    An overdose of Rosuvastatin 20mg and Ezetimibe 10mg can be potentially fatal, and thus requires emergency medical intervention. If you suspect an overdose, it is important to contact emergency services or go to the nearest emergency room immediately. In such a case, the treatment may involve providing supportive care, continuously monitoring the patient's vital signs, providing oxygen supplementation, and addressing any symptoms that may have arisen. Further, dialysis is not expected to be beneficial in mitigating the toxicity of these medications in an overdose case. In general, it is advised that you do not induce vomiting or attempt any countermeasures without first seeking professional medical guidance. Doing so may inadvertently cause further harm or complicate an already critical situation. It is important to consult a medical professional for appropriate treatment guidelines as the specific treatment involved will be adapted to the individual based on the severity of their condition, any concurrent medical conditions, and other factors.

  • Missed Dose

    Maintaining a regular medication schedule is vital, but sometimes life can intervene and cause a missed dose. If you've missed a dose, don't worry, there are steps you can take. If it's soon before your next scheduled dose, you can take the missed dose right away and continue as normal. However, if it's nearly time for your next dose, it's recommended you skip the missed dose and return to your regular schedule. It's always wise to consult your doctor, or the medication label, for specific instructions and precautions. For any further concerns, it's recommended to speak to your doctor or pharmacist for personalized guidance based on your health condition, medication, and any potential risks involved with missing a dose. They can also provide helpful advice on how to keep on track with your medication schedule in the future.

  • How To Use

    Rosuvastatin 20mg and Ezetimibe 10mg is a medication that should be taken orally, usually once a day in the evening. This can be done with or without food. The medication should be consumed whole, but if you have difficulty swallowing, it can be crushed and mixed with applesauce or yogurt just before taking it. It is important to take this medication regularly to get the full benefit from it. If you experience any allergic reaction or muscle pain, tenderness, or weakness, it is important to notify your doctor. Also, if you have any medical history, especially related to liver disease, kidney disease, diabetes, muscle pain or weakness, or allergies, it is important to let your doctor know. This medication should only be used if clearly needed during pregnancy, and you should discuss the risks and benefits with your doctor.

  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • Have experienced muscle pain, tenderness, or weakness while on this medication or similar treatments in the past. Significantly, this condition can worsen and lead to true muscle breakage that can be dangerous.
    • Have experienced liver dysfunction or have an increased risk for liver dysfunction. Taking Rosuvastatin may worsen this condition.
    • Have experienced mental depression or disorder. Rosuvastatin can increase the risk of depression, and combining it with Ezetimibe, which also has a similar effect, may exacerbate this condition.
    • Have a history of cancer, especially breast, liver, or prostate cancer. This condition can be made worse by the use of Rosuvastatin.
    • Have experienced kidney failure or dysfunction. This condition can be exacerbated by Rosuvastatin use.
    • Have experienced seizure, or have a history of seizure disorders. Rosuvastatin and Ezetimibe use may increase the risk of seizures.
    • Have any allergies to the ingredients in the medications, as well as similar ingredients in other medications. It is important to be aware of these allergies and to always read the label and cautionary statements on all medications.
    • Are pregnant, planning to become pregnant, or breastfeeding. It is generally advised to avoid taking Rosuvastatin and Ezetimibe during these times unless necessary, and to consult a medical professional. The implications of taking these drugs during pregnancy or breastfeeding are not fully known, although there is some risk of birth defects and reduced birth weight. It is important to weigh the potential benefits and risks before making a decision.
    • Have eaten a grapefruit or drank grapefruit juice within the last few days of taking Rosuvastatin. The chemicals in grapefruit interfere with the metabolism of Rosuvastatin, leading to too much of the drug in your system.
  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Muscle Pain
    • Nausea, Fatigue, Diarrhea, Constipation
    • Headache
    • Nosebleed
    • Muscle Cramps
    • Joint Pain
    • Depression
    • Upper Respiratory Infection
  • Storage/Disposal

    Rosuvastatin is a drug used to prevent cardiovascular disease and cerebrovascular events, meaning it helps reduce the levels of low-density lipoprotein (LDL) cholesterol, often referred to as "bad" cholesterol, in the blood. It is essential to follow the manufacturer's storage instructions to ensure the medication remains effective and safe for consumption. For Rosuvastatin tablets, ensure the container is tightly closed or sealed and store it at room temperature between 59°F and 86°F (15°C and 30°C). Importantly, avoid freezing the tablets, and protect them from exposure to excessive heat, moisture, direct sunlight, or X-rays. Similarly, Ezetimibe, when used with Rosuvastatin, is a medication that helps block the absorption of cholesterol in the intestines. It is essential to store Ezetimibe tablets in a similarly secure and closed container at room temperature between 59°F and 86°F (15°C and 30°C). They, too, should be shielded from excessive heat, moisture, and direct sunlight. By following these storage instructions, you can help maintain the effectiveness of these medications and ensure their safety for use. If you have further questions or concerns about storing these medications, consult your physician or pharmacist for guidance.

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