X-Plended EZ (5/10mg) 10 Tablets

Rosuvastatin is an orally active drug that is absorbed selectively in the intestine and metabolized by the liver. It is a potent inhibitor of HMG-CoA reductase, which is a key enzyme in the liver's cholesterol production process. By reducing cholesterol production, Rosuvastatin helps to lower low-density lipoprotein (LDL) cholesterol levels in the blood. Ezetimibe works differently from other cholesterol-lowering drugs. Rather than intervene in the liver's cholesterol synthesis, it specifically inhibits the absorption of cholesterol in the small intestine. It accomplishes this by blocking the Niemann-Pick C1-Like 1 (NPC1L1) protein from absorbing cholesterol, which reduces the levels of LDL cholesterol in the blood. When Rosuvastatin 5mg and Ezetimibe 10mg are used in combination, they provide a synergistic approach to reducing cholesterol levels by both limiting cholesterol absorption in the intestine and reducing cholesterol production in the liver. This helps to effectively manage high cholesterol and improve overall cholesterol levels.

Ezetimibe 10mg, Rosuvastatin 5mg

Rosuvastatin:

Tablet

Ezetimibe, Rosuvastatin combination is utilized for the following therapeutic indications:

• Reduction of LDL cholesterol levels
• Treatment of primary hyperlipidemia
• Management of dyslipidemia
• Cardiovascular risk reduction
• Used in patients requiring additional cholesterol-lowering therapy beyond monotherapy with statins

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• If you are taking both Rosuvastatin 5mg and Ezetimibe 10mg as advised by your doctor, it is important to follow your physician's dosage instructions considering several factors based on age, weight, gender, and the severity of your condition.
• If you are taking Rosuvastatin 5mg, it is recommended to take it at night because statins can elevate levels of lipids in the blood that can affect glucose tolerance and insulin sensitivity, more common in the morning than evening. Consult your doctor if you wish to change the time of your dosage.

If a patient is experiencing an overdose of Rosuvastatin 5mg and Ezetimibe 10mg, there is no specific treatment for this statin overdose. The patient will require general supportive care and monitoring of symptoms. However, medical professionals may consider several different approaches to treat the overdose. These include Gastric Lavage, which can limit the drugs' absorption if performed soon after ingestion. Activated charcoal can adsorb the drugs and limit their absorption if used within a few hours of ingestion. Cholestyramine, can be used to adsorb the statin drugs in the intestine and limit their absorption, however, this should only be used if the patient is unable to immediately reach a medical facility. It is not routinely recommended to perform hemodialysis due to the small amount of drug excreted by the kidneys within a few hours of ingestion. The most important aspect of treatment is monitoring for signs and symptoms of muscle injury and monitoring kidney function regularly. The patient may require close monitoring of liver and kidney function, as well as frequent serum cholesterol and liver function tests. Note that these recommendations may vary based on a patient's individual situation and the resources available in an emergency setting. It is always recommended to consult a medical professional for the most appropriate treatment advice specific to a particular patient.

If you have missed a dose of your medication, it is important to take it as soon as possible. However, if it is almost time for your next scheduled dose, it is recommended to skip the missed dose and proceed with your regular dosing schedule. It is crucial to avoid double dosing as it can result in adverse effects. If you are uncertain about the next steps after missing a dose, it is advised to contact your doctor or pharmacist for guidance. Consistent and timely medication intake, along with adherence to the prescribed dosage, is essential to achieve the desired therapeutic effect. It is paramount not to cease or adjust the medication without professional medical supervision as it may lead to adverse consequences and deterioration of the medical condition.

When taking the Rosuvastatin 5mg and Ezetimibe 10mg tablets, it's essential to follow your doctor's directions and precautions carefully. Here are some essential guidelines to follow:

Discerning instances where this medication may not be appropriate:

• Have had an allergic reaction to either of the drugs or any of their ingredients.
• Have experienced muscle pain, tenderness, or weakness with active liver disease or while taking another cholesterol-lowering medication.
• Have a history of liver disease or drink more than two alcoholic beverages per day.
• Have cancer or a history of breast cancer.
• Have a history of gastrointestinal issues or liver disease.
• Are pregnant or planning to become pregnant.
• Are breastfeeding.

Unraveling the side effects lurking behind this medications are as follows:

• Muscle Pain/Tightness or Weakness
• Joint Pain
• Fatigue
• Nausea
• Digestive Issues
• Headaches
• Nose Bleeds
• Skin Rash

Rosuvastatin and Ezetimibe are two different medications that are often prescribed together to treat high cholesterol levels. These medications are typically prescribed when lifestyle changes such as diet and exercise are not sufficient on their own. While Rosuvastatin works by inhibiting the production of cholesterol in the liver, Ezetimibe blocks the absorption of cholesterol in the small intestine. When used together in conjunction with a healthy lifestyle, these medications help to significantly lower cholesterol levels in the blood. In order to ensure the effectiveness and longevity of these medications, it is important to follow specific storage instructions. Here are some recommended steps for storing Rosuvastatin and Ezetimibe: