Xenglu (25mg) 14 Tablets

Xenglu (25mg) 14 Tablets

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  • Manufacturer Hilton Pharma (Pvt.) Ltd.
  • Generic Name Empagliflozin

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Storage/Disposal
  • Description

    Empagliflozin is a drug used to treat adults with type 2 diabetes mellitus. It helps restore the body's response to insulin, a natural hormone that helps control blood sugar levels. Working as a sodium-glucose cotransporter-2 (SGLT-2) inhibitor, empagliflozin increases the excretion of glucose in the urine, blocking the SGLT-2 proteins responsible for reabsorbing glucose in the kidneys, and thereby helping to lower blood sugar levels. This medication is often prescribed alongside lifestyle adjustments such as healthy eating and regular exercise. Despite being a common treatment for type 2 diabetes, it is important to consult a healthcare professional before taking this medication to ensure it is the right treatment plan for you. Diabetes is a complex condition and every individual will require different care and treatment.

  • Ingredients

    Empagliflozin
  • Drug Class

    Sodium-Glucose Co-Transporter 2 (SGLT2) Inhibitor

  • Dosage Form

    Tablet
  • Uses

    Unveiling its multifaceted uses and transformative applications as follows:

    • Lowering blood sugar levels in people with type 2 diabetes.
    • Reduce the risk of heart attacks, strokes, and death in people with diabetes.
    • Reduce the risk of death from heart disease in people with diabetes and heart disease.
    • Lower chance of getting diabetic eye disease.
    • Lower chances of kidney damage.
    • Lowers chances of going on dialysis due to kidney damage.
    • Reduces the risk of death in people with diabetes and kidney disease.
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • For treatment of type 2 diabetes Adults 10 mg or 25 mg once daily
    • Adults with a high risk of complications Initially 10 mg once daily for 1 month, then increase to 25 mg once daily
    • For reduction of cardiovascular risk in adults with type 2 diabetes and cardiovascular disease Greater than 10 mg / day and No initial dose adjustment required. Greater than 10 mg / day and less than 10 mg / day and Consider reducing the empagliflozin dose to 10 mg / day
    • For the treatment of obesity in adults Placebo or 10 mg once daily
  • In case of Overdose

    An Empagliflozin overdose can be life-threatening, and immediate medical attention is required in such cases. The first step involves inducing emesis (vomiting) to remove the excess drug from the body if the overdose recently occurred. To reduce the amount of drug absorbed, activated charcoal may be given, which binds and neutralizes it in the digestive tract. In more severe cases, specific medications aimed at treating hypoglycemia (low blood sugar) and regulating blood glucose levels may be administered, which can include glucose solutions, insulin, or glucagon.

  • Missed Dose

    Maintaining a regular medication schedule for drugs like Empagliflozin 25mg is crucial. If you miss a dose, you should take it as soon as possible, except if it's almost time for the following scheduled dose. In this case, it's safer to skip the missed dose and continue with your regular schedule. It's imperative to avoid doubling up or taking extra medication to make up for a missed dose, as it can lead to an overdose or adverse side effects. It's also important to consult a doctor or healthcare professional before taking any medication, especially if you miss a dose.

  • How To Use

    Before starting your medication, it is important to read the provided medication guide and consult your doctor or pharmacist for any concerns. The dosage of Empagliflozin 25mg is tailored to the child's age, weight, and the severity of their condition. It is usually taken once daily with or without food. For the best results in treating diabetes, it is crucial to monitor blood sugar levels and adjust diet, exercise, and medication accordingly. It is also important to continue taking the medication as directed by your doctor, even if you feel well. Stopping without medical consultation can lead to relapse. Be sure to store the medication safely, away from heat, moisture, light, and out of the reach of children and pets. Keep in mind that these instructions may vary based on your specific formulation and strength, so it's always best to refer to the instructions provided with your medication. Remember to consult your doctor or pharmacist if you have any further questions or concerns about using Empagliflozin 25mg.

  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • If you are allergic to empagliflozin or any of the other ingredients in this medication.
    • If you have type 1 diabetes, severe kidney disease, or diabetic ketoacidosis.
    • If you have metabolic acidosis that is not related to diabetes.
    • If you are in a state of diabetic pre-coma or coma.
    • If you are taking captopril or ramipril, and have renal artery stenosis.
    • If you are pregnant or planning to become pregnant, or breastfeeding.
    • If you have any severe gastrointestinal issues including inflammatory bowel disease or bowel obstruction.
    • If you have any conditions that require you to limit your potassium, magnesium, or calcium levels.
    • If you have urea cycle disorders, or conditions that affect the metabolism of ammonia.
    • If you have any severe illnesses or are in acute severe stress.
  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Edema
    • Bone Fracture
    • Hypoglycemia
    • Upper Respiratory Infection
    • Headache
    • Diarrhea
    • Muscle Pain
  • Precautions & Warnings

    Patients should be aware of these precautions and warnings before using this product:

    • Use with caution in individuals with cardiovascular disease, a history of hypotension, or those at risk for acute kidney injury, including conditions like hypovolaemia or chronic kidney insufficiency.
    • Be cautious in patients with risk factors for ketoacidosis, such as low β-cell function reserve, pancreatic disorders suggesting insulin deficiency (e.g., history of pancreatitis or pancreatic surgery), insulin dose reduction, caloric restriction, alcohol abuse, acute febrile illness, or severe dehydration.
    • Consider patients with a history of genitourinary fungal infections or those with risk factors for amputation (e.g., prior amputation, peripheral vascular disease, neuropathy, diabetic foot ulcers). Also, note special considerations for uncircumcised males.
    • This product is not indicated for use in patients with type 1 diabetes mellitus or diabetic ketoacidosis.
    • Temporarily discontinue treatment at least 3 days before any surgery.
    • Use with caution in individuals with renal or severe hepatic impairment, and in the elderly.
    • Avoid use during pregnancy.
  • Drug Interactions

    Drug interactions with empagliflozin include:

    • Diuretics (e.g., furosemide) (may increase the risk of dehydration and hypotension- monitor for volume status and blood pressure)
    • ACE inhibitors (e.g., lisinopril) (may enhance hypotensive effect- monitor blood pressure)
    • Angiotensin II receptor blockers (ARBs) (e.g., losartan) (may enhance hypotensive effects- monitor blood pressure)
    • Insulin and other antidiabetic agents (e.g., sulfonylureas) (may increase the risk of hypoglycemia- monitor blood glucose levels)
    • Rifampin (may decrease empagliflozin levels- monitor for reduced efficacy)
    • Strong CYP3A4 inducers (e.g., carbamazepine) (may decrease empagliflozin levels- monitor for reduced efficacy)
    • Strong CYP3A4 inhibitors (e.g., ketoconazole) (may increase empagliflozin levels- monitor for increased side effects)
    • Non-steroidal anti-inflammatory drugs (NSAIDs) (e.g., ibuprofen) (may increase the risk of renal impairment- monitor renal function)
    • Lithium (may increase the risk of lithium toxicity- monitor lithium levels)
  • Storage/Disposal

    Empagliflozin is a drug that should be stored in a cool, dry location that maintains a consistent room temperature of 25°C/77°F. Such an area should be away from direct heat and light, like a windowsill. It should also be kept away from bathrooms or sinks, as the high humidity levels in these areas can negatively affect the drug's composition. Empagliflozin should be stored in a secure location, out of the reach of children and pets as it can be dangerous if ingested without proper caution and medical supervision. If you have any questions about the proper storage of Empagliflozin 25 mg, it is vital to consult a physician or pharmacist for guidance regarding this medication's storage conditions and other inquiries you may have.

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