Xenical (120mg) 21 Capsules

Orlistat 120mg, a lipase inhibitor, primarily targets the absorption of dietary fats in the gastrointestinal tract. Its mechanism of action revolves around inhibiting pancreatic and gastric lipases, enzymes responsible for breaking down triglycerides into absorbable free fatty acids and monoglycerides. By blocking these lipases, Orlistat prevents the breakdown and subsequent absorption of approximately 30% of dietary fat, leading to reduced calorie intake and aiding in weight management. This unabsorbed fat is then excreted from the body.

Lipase inhibitor.

Capsule

The following are the uses of Orlistat 120mg Capsule:

• Used for weight management by preventing fat absorption in the intestines.
• Effective for obesity treatment, helping individuals lose and maintain weight.
• Aids in reducing the risk of weight-related health issues such as type 2 diabetes and high cholesterol.
• Assists in promoting healthy eating habits and lifestyle changes.
• Can be used in conjunction with a reduced-calorie diet for enhanced weight loss results.
• Helps individuals reach their weight loss goals and improve overall well-being.
• Provides support for long-term weight management and lifestyle modification.

In the case of an overdose of Orlistat 120mg capsules, it is important to recognize the symptoms, which may include severe stomach pain, diarrhea, and potential liver issues. If an overdose is suspected, seek medical advice promptly. The healthcare provider may recommend monitoring and supportive care, focusing on managing any discomfort and ensuring the patient's well-being. Timely intervention can help mitigate the risks associated with an overdose.

In the case of a missed dose of Orlistat 120mg Capsule, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. It is important not to double the dose to make up for a missed one. If you frequently miss doses, inform your healthcare professional, as they may provide guidance on how to manage your medication routine more effectively.

To take Orlistat 120mg Capsule, swallow the capsule whole with a glass of water during or up to one hour after each main meal (containing fat), following the dosage instructions provided by your healthcare professional, typically one capsule three times a day.

Following are the conditions or situations when Orlistat 120mg Capsule should not be taken:

• Should not be taken by individuals with known hypersensitivity or allergy to Orlistat or any of its inactive ingredients.
• Not recommended for use during pregnancy as it may affect fetal development.
• Contraindicated in patients with chronic malabsorption syndrome or cholestasis, as it may worsen these conditions.
• Should not be used in individuals with a history of liver problems or current liver disease.
• Not suitable for individuals with kidney failure or severe kidney impairment.
• Avoid use if you have had organ transplant surgery.
• Do not take if you have a history of problems with your gallbladder.

The side effects of Orlistat 120mg Capsule may include:

• Frequent or urgent bowel movements
• Oily or fatty stools
• Gas (flatulence)
• Abdominal pain or discomfort
• Nausea
• Vomiting
• Headache
• Fatigue or weakness
• Increased bowel movements

Here are the precautions and warnings for Orlistat 120mg Capsule:

• Not suitable for individuals with known allergies to Orlistat or any of its components.
• Orlistat may reduce the absorption of fat-soluble vitamins (A, D, E, and K); therefore, vitamin supplementation may be necessary.
• Patients with a history of liver problems should exercise caution, as liver function tests may be required during treatment.
• This medication should be used with caution in patients with chronic malabsorption syndrome or cholestasis.
• May cause gastrointestinal side effects; patients should maintain adequate hydration and promptly report any severe or persistent symptoms.
• Not recommended for use during pregnancy or while breastfeeding, as its effects on fetal development and nursing infants are not fully understood.
• Patients should follow a well-balanced, low-fat diet to maximize the benefits of Orlistat and minimize potential gastrointestinal side effects.
• Consult a healthcare professional before use if you have any underlying medical conditions or are taking other medications.

Following are the drug interactions for Orlistat 120mg Capsule:

• Concomitant use with cyclosporine can increase blood levels of cyclosporine, requiring close monitoring and potential dose adjustment.
• Orlistat may reduce the absorption of certain fat-soluble vitamins (A, D, E, K) and beta-carotene, necessitating supplementation if used long-term.
• Anticoagulants like warfarin may have their effects altered, requiring monitoring of INR and potential dose adjustments.
• Interactions with levothyroxine can reduce its absorption, possibly requiring adjustments in levothyroxine dosing.
• Antiepileptic medications (e.g., valproate, lamotrigine) may have decreased absorption, requiring monitoring of blood levels and potential dose adjustments.
• Drugs like amiodarone, acarbose, and miglitol can be affected by Orlistat, potentially reducing their effectiveness.
• The absorption of certain HIV medications (e.g., atazanavir, darunavir, lopinavir, saquinavir) may be reduced, leading to decreased effectiveness of these drugs.

Following are the food interactions for Orlistat 120mg Capsule:

• Avoid high-fat meals as Orlistat blocks the absorption of dietary fats, and consuming excessive fat may lead to increased gastrointestinal side effects.
• Reduce fat intake to 30% or less of your total daily calories to minimize digestive issues.
• Avoid foods with a high fat content, such as fatty meats, full-fat dairy products, and fried foods.
• Consume a well-balanced diet with a variety of fruits, vegetables, whole grains, and lean proteins.
• Orlistat may reduce the absorption of fat-soluble vitamins (A, D, E, and K). Consider a multivitamin supplement, but take it at least 2 hours before or after Orlistat.
• Avoid excessive alcohol consumption as it can increase the risk of liver-related side effects.
• Some studies suggest that consuming foods rich in medium-chain triglycerides (MCTs), like coconut oil, may reduce the effectiveness of Orlistat.

Orlistat 120mg capsules should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. It is crucial to keep the medication in its original packaging, tightly sealed, to maintain its integrity. Avoid storing it in areas exposed to heat, such as near kitchen appliances or in direct sunlight, as this can degrade the medication. Always refer to the packaging for the expiration date, and do not use the capsules beyond this date. When disposing of unused or expired Orlistat, do not flush or pour it down the drain; instead, consult your pharmacist or local waste management guidelines for safe disposal methods. Keep this medication securely stored away from children to prevent accidental consumption.

Following are the quick tips for Orlistat 120mg Capsule:

• Consult your doctor before taking this medication to ensure it's suitable for you.
• Take the capsule as directed, typically with a meal or up to an hour after eating.
• Stick to a balanced, low-fat diet while taking this medication for best results.
• Avoid high-fat meals as they can reduce the medication's effectiveness.
• Orlistat may cause some dietary fats to pass directly through your digestive system, leading to oily stools.
• Multivitamins are recommended daily, at least 2 hours before or after taking Orlistat, to ensure vitamin absorption.
• Store the capsules in their original packaging at room temperature, away from moisture and heat.