Xylor (5mg/5ml) 60ml Syrup

Loratadine is a second-generation antihistamine that selectively blocks peripheral histamine H1 receptors. Its primary mechanism of action is to inhibit the binding of histamine to these receptors, thereby preventing the activation of downstream cellular responses. Loratadine's selectivity for peripheral H1 receptors helps reduce the likelihood of crossing the blood-brain barrier and causing central nervous system-related side effects. By blocking the histamine-induced response, loratadine effectively reduces symptoms associated with allergic reactions, such as sneezing, itching, and nasal congestion, providing relief without causing drowsiness or sedation, which is commonly associated with older antihistamines.

Loratadine 5mg

Antihistamine

Suspension

The following are the uses of Loratadine 5mg Syrup/Suspension:

• Used for relieving symptoms of seasonal allergies like sneezing, runny nose, and itchy eyes.
• Used for treating allergic rhinitis and its associated discomfort.
• Used to manage chronic hives and skin itching, providing relief.
• Used to reduce congestion and inflammation caused by allergies.
• Used for easing symptoms of pet allergies, pollen allergies, and dust allergies.
• Used for preventing allergic reactions during outdoor activities.
• Used to improve sleep quality for those with nighttime allergies.

In the case of an overdose of Loratadine 5mg Syrup/Suspension, symptoms may include drowsiness, rapid heartbeat, and confusion. The severity of these symptoms can vary depending on the amount ingested. It is important to seek medical advice or contact a poison control center for guidance. Quick action can help mitigate potential health risks, especially in children, who may be more susceptible to the effects of an overdose. Prompt medical assessment and intervention are key to managing any adverse effects.

In the case of a missed dose of Loratadine 5mg Syrup/Suspension, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you have missed multiple doses, consult your healthcare professional for advice on how to get back on track with your medication regimen.

To administer Loratadine 5mg Syrup/Suspension, shake the bottle thoroughly, measure the prescribed dose with an accurate measuring device like a dosing spoon or oral syringe, and give it to the patient once daily, either with or without food, following the dosage instructions provided by a healthcare professional or the product label, ensuring not to exceed the recommended amount.

Here are the conditions or situations when Loratadine 5mg Syrup/Suspension should not be used:

• Not suitable for individuals with a known allergy to Loratadine or related antihistamines.
• Should not be used in patients with a history of liver or kidney disease.
• Contraindicated in patients with a rare hereditary problem of fructose intolerance.
• Not recommended for children under 2 years of age due to potential risks.
• Avoid use if you have a severe allergy or hypersensitivity to any of the inactive ingredients in the syrup/suspension.
• Do not administer if the patient is currently taking certain medications that may interact with Loratadine, such as erythromycin or ketoconazole.

The side effects of Loratadine 5mg Syrup/Suspension may include:

• Drowsiness or fatigue
• Headache
• Dry mouth or throat irritation
• Nausea or stomach discomfort
• Diarrhea
• Dizziness
• Skin rash or itching
• Difficulty concentrating

Following are the precautions and warnings for Loratadine 5mg Syrup/Suspension:

• Do not use if you are allergic to Loratadine or any of the inactive ingredients in the syrup.
• Loratadine may cause drowsiness or dizziness in some individuals, so avoid driving or operating heavy machinery until you know how the medication affects you.
• If you have a medical condition such as liver or kidney disease, consult your doctor before taking this medication as it may require dosage adjustments.
• Avoid alcohol consumption while taking Loratadine as it can increase the risk of side effects.
• Do not exceed the recommended dosage; an overdose may lead to serious health complications.
• Keep out of reach of children. In case of accidental overdose, seek medical attention immediately.
• Consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding before using this medication.

Following are the drug interactions for Loratadine 5mg Syrup/Suspension:

• Alcohol may cause increased drowsiness and sedation when taken with Loratadine.
• Medications that cause drowsiness, such as benzodiazepines, opioids, or certain antidepressants, can enhance the sedative effects of Loratadine.
• Macrolide antibiotics (e.g., erythromycin) and antifungal medications (e.g., ketoconazole) may inhibit the metabolism of Loratadine, leading to increased drug levels in the body.
• Loratadine can potentially interact with antiepileptic drugs like phenytoin and carbamazepine, affecting their blood levels.
• Grapefruit juice may inhibit the metabolism of Loratadine, leading to increased drug exposure.
• The effectiveness of Loratadine may be reduced when taken with antacids containing aluminum and magnesium.
• Loratadine can increase the concentration of certain HIV protease inhibitors, such as ritonavir, in the blood.

Following are the food interactions for Loratadine 5mg Syrup/Suspension:

• Loratadine can be taken without regard to meals, as food does not significantly affect its absorption.
• Grapefruit and grapefruit juice consumption should be avoided as it may increase the concentration of Loratadine in the blood, leading to potential side effects.
• Alcohol may cause increased drowsiness and sedation when combined with Loratadine, so it's best to limit or avoid alcohol consumption during treatment.
• Caffeine intake should be monitored as it may counteract the sedating effects of Loratadine, potentially reducing its effectiveness in alleviating allergy symptoms.
• There is no specific food restriction with Loratadine, but maintaining a balanced diet is advisable to support overall health.
• Avoid excessive consumption of citrus fruits, as they may slightly alter the drug's metabolism.
• Always follow your healthcare provider's instructions regarding dietary restrictions or recommendations while taking this medication.
• Inform your doctor if you have any specific dietary concerns or restrictions to ensure safe and effective use of Loratadine.

Loratadine 5mg Syrup/Suspension should be stored with caution, preferably in a dry and cool place, ensuring it remains protected from direct sunlight and moisture. Keep the medication securely sealed within its original container to maintain its integrity and prevent contamination. It is crucial to avoid storing it in areas like the bathroom or near heat-emitting appliances, as extreme temperatures can compromise the medicine's effectiveness. Always verify the expiration date, and if the medication is no longer needed or has expired, do not dispose of it by flushing or pouring it down the drain. Instead, consult a pharmacist or healthcare professional for guidance on safe disposal practices. Additionally, ensure the medication is stored out of children's reach to prevent accidental consumption.

Following are the quick tips for Loratadine 5mg Syrup/Suspension:

• Always follow your healthcare provider's instructions for dosage and duration of treatment.
• Shake the bottle vigorously before each use to ensure proper mixing.
• Administer the syrup with a measuring cup or syringe provided to ensure accurate dosing.
• It can be taken with or without food, but taking it with a small snack may help prevent stomach upset.
• Avoid drinking fruit juices or carbonated drinks immediately after taking the syrup.
• Store the syrup at room temperature, away from direct sunlight and moisture.
• Do not share your medication with others, even if they have similar symptoms.