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Zantum (1g) 1 Vial Injection
- Manufacturer Cell Laboratories (Pvt.) Ltd.
- Generic Name Cefoperazone, Sulbactam
Healthwire Pharmacy Ratings & Reviews (1500+)
Product Information
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Description
Cefoperazone is a cephalosporin antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis and death. Sulbactam is a beta-lactamase inhibitor that prevents bacterial enzymes from inactivating cefoperazone, thereby extending its spectrum of activity.
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Ingredients
Cefoperazone, Sulbactam -
Drug Class
Cephalosporin antibiotic, Beta-lactamase inhibitor
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Dosage Form
injection
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Uses
Cefoperazone is primarily indicated in conditions like Bone and joint infection, Pelvic inflammatory disease, Peritonitis, Respiratory tract infections, Septicaemia, Skin infections, Urinary tract infection.
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Dosage
Cefoperazone/Sulbactam dosage for the indication of severe bacterial infections, with a duration of 5-14 days:
- Adults - 1-2 g every 12 hours.
- Children - 50-100 mg/kg/day in 2 divided doses.
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In case of Overdose
Overdose may lead to gastrointestinal distress or kidney issues. Seek medical attention for symptomatic treatment.
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Missed Dose
If you miss a dose, consume as soon as you remember. If it is close to the next feeding, skip the missed dose. Do not double up on doses.
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How To Use
Cefoperazone and sulbactam are administered via intravenous injection. Follow the healthcare provider's instructions for dosage and administration.
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When Not to Use
Cefoperazone, Sulbactam should not be used if:
- Hypersensitivity
- Severe renal impairment
- History of colitis
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Side Effects
Unraveling the side effects lurking behind this product are the following:
Anemia
GI bleeding
Leucopenia
Hemolytic anemia
Bleeding
Lymphocytosis
Bone marrow depression
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Precautions & Warnings
Cefoparazone should be used with caution in patients with impaired kidney or liver function. Appropriate measure should be taken if secondary infection occurs.
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Drug Interactions
The drug interactions with cefoperazone and sulbactam include:
- Calcium-containing Solutions – Can form precipitates.
- Anticoagulants (e.g., warfarin) – Can increase bleeding risk.
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Food Interactions
The food interactions that should be considered while using cefoperazone and sulbactam are:
- Avoid alcohol consumption during treatment and for 72 hours after, as it can cause a disulfiram-like reaction.
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Storage/Disposal
Store Cefoperazone and Sulbactam at room temperature, away from light and moisture. Keep them in their original containers and out of reach of children. Dispose of any expired or unused medications according to local disposal guidelines or through a drug take-back program.
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