Zeldox (60mg) 14 Capsules

Zeldox (60mg) 14 Capsules

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  • Manufacturer PFIZER LABORATORIES LTD
  • Generic Name Ziprasidone

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    Ziprasidone, a 60mg capsule, primarily exerts its therapeutic effects by interacting with multiple neurotransmitter receptors in the brain. It acts as an antagonist at dopamine receptors, specifically D2 and D3 receptors, which helps to reduce positive symptoms of schizophrenia, such as hallucinations and delusions. Additionally, ziprasidone blocks serotonin receptors, particularly 5-HT2A and 5-HT2C receptors, contributing to its antipsychotic and mood-stabilizing properties. This dual mechanism of action helps regulate dopamine and serotonin activity, leading to improved symptoms in individuals with schizophrenia and other mental health conditions.

  • Ingredients

    Ziprasidone
  • Drug Class

    Atypical antipsychotic.

  • Dosage Form

    Capsule

  • Uses

    The following are the uses of Ziprasidone 60mg Capsule:

    • Used for treating schizophrenia, a mental health condition with symptoms like hallucinations and delusions.
    • Used to manage bipolar disorder, helping stabilize moods and reduce manic episodes.
    • Effective in reducing symptoms of agitation and aggression in various mental health disorders.
    • Helps in managing severe anxiety disorders by controlling symptoms.
    • Can be prescribed for off-label uses like treatment-resistant depression and eating disorders.
    • Assists in alleviating behavioral problems associated with dementia and Alzheimer's.
    • May be used to treat severe behavioral issues in children with autism.
    • Provides short-term relief from acute psychotic episodes, promoting stabilization.
  • In case of Overdose

    In the case of an overdose of Ziprasidone 60mg Capsules, it is important to act swiftly. Symptoms may include rapid heartbeat, dizziness, and fainting. If an overdose is suspected, seek medical assistance immediately. Call emergency services and provide them with the medication details. They will guide you on the necessary steps to ensure the individual receives prompt and appropriate treatment to mitigate the risks associated with the overdose.

  • Missed Dose

    In the case of a missed dose of Ziprasidone 60mg Capsule, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss several doses, contact your healthcare provider for guidance, as they may recommend adjusting your dosage or provide specific instructions to help you get back on track with your medication regimen.

  • How To Use

    To take Ziprasidone 60mg Capsule, swallow the capsule whole with water, preferably at the same time each day, as directed by your healthcare provider, and ensure you complete the prescribed course of medication.

  • When Not to Use

    Here are the conditions and situations when Ziprasidone 60mg Capsule should not be taken:

    • Should not be used in individuals with a known allergy to Ziprasidone or other similar antipsychotic medications.
    • Not suitable for individuals with a history of cardiovascular problems, including heart disease, recent heart attack, or irregular heart rhythms.
    • Contraindicated in patients with a personal or family history of Long QT syndrome.
    • Should not be used in individuals with severe liver or kidney impairment.
    • Not recommended for elderly patients with dementia-related psychosis, as it can increase the risk of death.
    • Contraindicated in patients with uncontrolled seizure disorders.
    • Should be avoided in patients with low white blood cell counts or a history of low white blood cell counts.
    • Not suitable for individuals with severe gastrointestinal conditions, such as paralytic ileus or severe constipation.
  • Side Effects

    The side effects of Ziprasidone 60mg Capsule may include:

    • Dizziness or lightheadedness
    • Headache
    • Nausea and vomiting
    • Dry mouth
    • Diarrhea
    • Restlessness or agitation
    • Muscle stiffness or spasms
    • Sleep disturbances
  • Precautions & Warnings

    Following are the precautions and warnings for Ziprasidone 60mg Capsule:

    • Do not use if you are allergic to Ziprasidone or similar medications.
    • Patients with a history of cardiovascular diseases should be closely monitored as this medication may cause changes in heart rhythm.
    • It may cause dizziness or lightheadedness; patients should rise slowly from a sitting or lying position to prevent falls.
    • This medication can increase the risk of stroke, especially in elderly patients with dementia-related psychosis.
    • Avoid alcohol consumption while taking Ziprasidone as it may enhance side effects.
    • Patients with a history of seizures or conditions that lower the seizure threshold should be cautious as Ziprasidone may lower the seizure threshold.
    • Pregnant or breastfeeding women should consult their doctor as the risks and benefits should be carefully evaluated before use.
  • Drug Interactions

    Following are the drug interactions for Ziprasidone 60mg Capsule:

    • Concomitant use with other antipsychotics, such as haloperidol or risperidone, can increase the risk of QT prolongation, leading to cardiac arrhythmias.
    • Ziprasidone may lower the seizure threshold; caution is advised when used with other medications that lower the seizure threshold, like certain antidepressants or tramadol.
    • It can interact with medications metabolized by the liver enzyme CYP3A4, including some calcium channel blockers, statins, and certain benzodiazepines, potentially altering their effects.
    • Antihistamines and other medications that cause drowsiness may have additive effects when taken with Ziprasidone, leading to increased sedation.
    • Ziprasidone may increase the effects of certain antihypertensive medications, resulting in low blood pressure.
    • Caution is needed with diuretics, especially if they cause electrolyte imbalances, as Ziprasidone may also affect electrolyte levels.
    • It may increase the blood levels of certain beta-blockers, enhancing their effects and potential side effects.
  • Food Interactions

    Following are the food interactions for Ziprasidone 60mg Capsule:

    • Consuming grapefruit or grapefruit juice should be avoided as it may interfere with the metabolism of Ziprasidone, leading to increased drug levels and potential side effects.
    • Alcohol consumption should be minimized or avoided as it can enhance the sedative effects of Ziprasidone, causing excessive drowsiness and impaired coordination.
    • Foods high in fat can affect the absorption of Ziprasidone; it is advisable to maintain a consistent dietary pattern to ensure stable drug levels.
    • Avoid excessive caffeine intake as it may exacerbate nervousness and insomnia, especially when starting Ziprasidone treatment.
    • Do not consume large meals immediately after taking Ziprasidone, as it may impact the drug's absorption and effectiveness.
    • Ensure adequate hydration and maintain a balanced diet to support overall health during the medication period.
    • Certain high-potassium foods like bananas, oranges, and tomatoes should be consumed in moderation to prevent potential electrolyte imbalances.
    • Always follow the medication guidelines provided by your healthcare professional regarding food and drug interactions.
  • Storage/Disposal

    Ziprasidone 60mg Capsules should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. It is crucial to keep the capsules in their original packaging, tightly sealed, to maintain their integrity and prevent contamination. Avoid storing them in bathrooms or areas exposed to heat, as temperature fluctuations can impact the medication's effectiveness. Dispose of any unused or expired capsules responsibly by consulting a pharmacist or healthcare professional for guidance on proper disposal methods. Keep the medication away from children to prevent accidental consumption, and always check the expiration date before use.

  • Quick Tips, if any

    Following are the quick tips for Ziprasidone 60mg Capsule:

    • Take the capsule as directed by your doctor, usually once or twice daily with food.
    • Swallow the capsule whole with a full glass of water; do not crush, chew, or open it.
    • Ensure you finish the entire course of medication as prescribed.
    • Avoid alcohol consumption as it may intensify side effects.
    • Inform your doctor about all medications you are taking to prevent potential drug interactions.
    • Store the capsules in a cool, dry place, away from direct sunlight and moisture.
    • Do not share your medication with others, even if they have similar symptoms.

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