Zetro (500mg) 6 Tablets

Azithromycin is a macrolide antibiotic that binds to the P-50 subunit of the bacterial ribosome in the cytosol, preventing the binding of ATP and causing the energy required for peptide bond formation to be unavailable. This terminates peptide elongation and protein synthesis, leading the bacterial cell to die. It is effective against intracellular bacteria and is commonly used to treat a variety of bacterial infections. Due to its long half-life, it only needs to be ingested less frequently compared to other antibiotics. It is normally used as a second-line antibiotic when initial treatments have failed. Therefore, Azithromycin's mechanism of action is effective in treating bacterial infections due to its macrolide properties, and its long half-life. This makes it a convenient treatment option for patients who have failed initial treatments.

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Macrolide Antibiotics

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Tablet

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Unveiling its multifaceted uses and transformative applications as follows:

• Treats a wide range of bacterial infections.
• Effective for treating genital infections, pneumonia, strep throat, and skin infections.
• Useful for preventing malaria, especially in travelers to regions where malaria is common.
• Useful for treating diarrhea associated with Clostridium difficile infection.
• Approved for use in children above the age of 1 for selected infections.

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Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• The recommended dosage of Azithromycin for treating pneumonia is 500 mg once a day for 3 consecutive days.
• For Chlamydia trachomatis infections, a single dose of 1000 mg is recommended.
• For sexually transmitted infections, the recommended dosage is 500 mg once followed by 500 mg on the next day.

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An Azithromycin 500mg overdose can cause serious harm to the body and should be treated as a medical emergency. If you recognize this has happened to you or someone else, it is important to seek immediate medical attention. Treatment for this overdose may include various interventions and procedures such as emesis and gastric lavage, which is the process of inducing vomiting and cleaning the stomach to remove the extra medication present. Activating charcoal is another procedure that involves binding the medication in the stomach, ensuring it does not absorb into the bloodstream and cause further damage. General supportive care will also be implemented, monitoring vital signs, managing any complications, and assuring proper fluid and nutrient consumption is met. Additional medications may be prescribed by a healthcare provider as per the specific symptoms and situation. It is imperative to seek medical attention as soon as possible for proper and timely treatment of an Azithromycin overdose.

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When taking Azithromycin 500mg, it is critical to adhere to the prescribed dosage schedule, but if you miss a dose, you should take it as soon as possible. If it is nearly time for your next dose, though, you should skip the missed dose and resume your regular dosage schedule. It is important to avoid doubling up on doses, as this may increase the likelihood of adverse side effects. If you have any questions or concerns about your dosage or experience any adverse side effects, be sure to consult a medical professional or follow the advice of the doctor who prescribed the medication.

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Before you take Azithromycin, ensure you talk to your healthcare provider and follow the instructions they give you. Also, it is important to adhere to the following steps:

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Discerning instances where this medication may not be appropriate:

• Known Allergy to Azithromycin or any other macrolide antibiotic.
• Severe Liver or Kidney Disease.
• If you are pregnant or breastfeeding.
• Interaction with other Drugs such as blood thinners, stomach treatment medication, and sedatives.
• Symptoms due to viral infections.
• Remember Azithromycin is only effective against bacterial infections.
• If you have any concerns or potential interactions with the aforementioned points, please consult your healthcare provider for advice.

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Unraveling the side effects lurking behind this medications are as follows:

• Rashness
• Mouth irritation, including tongue, lips, and cheeks
• Esophagus inflammation
• Abdominal pain
• Loose stools/diarrhea
• Constipation
• Nausea
• Vomiting
• Headache
• Fatigue or tiredness
• Less appetite
• Metallic or strange taste in the mouth
• Increased thirst
• Joint pain

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The warnings and precautions associated with Azithromycin are:

• Patients with history of hypersensitivity to azithromycin, erythromycin, or other macrolides.
• Severe hepatic impairment.
• QT prolongation or risk factors for cardiac arrhythmias (e.g., congenital or documented QT prolongation, uncorrected hypokalemia or hypomagnesemia).
• Use with caution in patients with myasthenia gravis.
• Renal impairment (GFR <10 ml/min).
• Pregnancy and lactation.

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The drug interactions with azithromycin include:

• Antacids – Azithromycin absorption may be reduced if taken with antacids containing aluminum or magnesium.
• Warfarin – May enhance the anticoagulant effect of warfarin, increasing the risk of bleeding.
• Digoxin – Azithromycin may increase digoxin levels, leading to potential toxicity.
• Cyclosporine – Azithromycin can increase cyclosporine levels, which may enhance the risk of adverse effects.
• Statins (e.g., simvastatin) – Azithromycin may increase the risk of statin-related myopathy or rhabdomyolysis.
• QT-Prolonging Drugs (e.g., certain antiarrhythmics) – Azithromycin may enhance the QT-prolonging effects of other drugs, increasing the risk of torsades de pointes.
• Ergot Alkaloids – Concomitant use may increase the risk of ergot toxicity.
• HIV Protease Inhibitors (e.g., ritonavir) – Can increase azithromycin levels, leading to an increased risk of side effects.

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For Azithromycin, food interactions that should be considered are:

• Taking with food may help reduce gastrointestinal side effects.

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Azithromycin is an antibiotic typically taken orally. It is important to follow the manufacturer's instructions or your physician's directions to ensure its effectiveness. Store this medication in a cool, dry place, away from direct sunlight and moisture, at room temperature (15-25°C). Keep it in its original container and out of reach of children and pets. Avoid storing it in bathrooms or areas prone to humidity. Properly dispose of any unused or expired medication according to local regulations or through a pharmacy take-back program to ensure safe disposal. Avoid flushing it down the toilet or pouring it into drains unless instructed to do so.

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