Zezot (200mg/5ml) 15ml Oral Suspension

Azithromycin 200mg/5ml Syrup/Suspension works by inhibiting bacterial protein synthesis. It specifically binds to the 50S subunit of bacterial ribosomes, preventing the translocation of aminoacyl-tRNA, which is essential for protein synthesis. This binding interferes with the ribosome's ability to read the genetic code, thereby halting the production of proteins required for bacterial growth and survival. The primary mechanism of action is through this protein synthesis inhibition, which leads to a rapid decline in bacterial viability and ultimately results in the eradication of the targeted bacteria.

Azithromycin 200mg/5ml

Macrolide antibiotic

Suspension

The following are the uses of Azithromycin 200mg/5ml Syrup/Suspension:

• Used for treating bacterial infections, such as respiratory tract infections, including pneumonia and bronchitis.
• Used for managing ear infections like otitis media, effectively clearing the infection.
• Used for curing throat infections, particularly strep throat, providing quick relief.
• Used for certain skin infections caused by susceptible bacteria.
• Used for gastrointestinal infections, ensuring a swift recovery.
• Used for preventing and treating sexually transmitted diseases like chlamydia.
• Used for managing Mycobacterium avium complex (MAC) infections in HIV patients.
• Used for providing quick relief from acute bacterial exacerbations in chronic obstructive pulmonary disease (COPD).

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Acute bacterial sinusitis- 500 mg once daily for 3 days
• Acute bacterial exacerbation of chronic bronchitis- 500 mg once daily for 3 days
• Community-acquired pneumonia- 500 mg once daily for 5 days
• Pharyngitis/tonsillitis/laryngitis- 500 mg once daily for 5 days
• Skin and soft tissue infections- 500 mg once daily for 3 days

In the case of an overdose of Azithromycin 200mg/5ml Syrup/Suspension, individuals may experience gastrointestinal symptoms such as nausea, vomiting, and diarrhea. Additionally, there could be an increased risk of cardiovascular side effects, including palpitations and irregular heart rhythms. It is crucial to seek medical advice promptly, as healthcare professionals can provide guidance and support to manage any adverse effects and ensure appropriate treatment. Timely intervention can help prevent potential complications from overdosing on this medication.

In the case of a missed dose of Azithromycin 200mg/5ml Syrup/Suspension, it is important to administer the medication as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to make up for the missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to adjust the dosing schedule to ensure the full course of treatment is completed effectively. It is essential to maintain consistency in taking the medication as prescribed.

To administer Azithromycin 200mg/5ml Syrup/Suspension, shake the bottle vigorously, then measure the prescribed dose using an accurate measuring device like a dosing spoon or oral syringe, and take it orally once daily, either with or without food, following the dosage instructions provided by your healthcare professional or as indicated on the medication label.

Here are the situations when Azithromycin 200mg/5ml Syrup/Suspension should not be used:

• Do not use if the patient has a known allergy to azithromycin or any macrolide-type antibiotics.
• Avoid using in patients with a history of myasthenia gravis.
• Not suitable for patients with a prolonged QT interval or heart rhythm disorders.
• Contraindicated in patients with liver impairment or severe kidney disease.
• Should not be used in patients with a history of jaundice or liver problems caused by previous azithromycin use.
• Do not administer to infants under 6 months of age.
• Avoid using in patients with conditions that may prolong QT interval, such as low potassium or magnesium levels in the blood.

The side effects of Azithromycin 200mg/5ml Syrup/Suspension may include:

• Nausea and vomiting
• Diarrhea
• Abdominal pain or discomfort
• Headache
• Dizziness
• Skin rashes or itching
• Fatigue or weakness
• Altered sense of taste

Following are the precautions and warnings for Azithromycin 200mg/5ml Syrup/Suspension:

• Do not use if you are allergic to Azithromycin or similar antibiotics such as erythromycin.
• This medication may cause a serious allergic reaction, including a rapid heartbeat, hives, and swelling. Seek immediate medical attention if this occurs.
• Azithromycin can interact with other medications; inform your doctor about all the medicines you are currently taking.
• Prolonged use may result in bacterial or fungal overgrowth, especially in patients with a history of prolonged or repeated antibiotic treatment.
• Elderly patients may be more susceptible to the side effects of this medication, particularly irregular heart rhythm.
• Caution is advised in patients with liver disease, as Azithromycin is primarily metabolized in the liver.
• Patients with myasthenia gravis should be closely monitored as Azithromycin may worsen their condition.

Following are the drug interactions for Azithromycin 200mg/5ml Syrup/Suspension:

• Concomitant use with other macrolide antibiotics or drugs that prolong the QT interval (e.g., antiarrhythmics, certain antipsychotics) may increase the risk of cardiac arrhythmias.
• Azithromycin may reduce the effectiveness of oral contraceptives, so alternative birth control methods are advised during treatment.
• Co-administration with antacids containing aluminum or magnesium can decrease the absorption of azithromycin, so they should be taken at least 2 hours apart.
• The drug can interact with ergotamine and dihydroergotamine, potentially leading to ergot toxicity.
• Azithromycin may increase the concentration of digoxin, requiring close monitoring of digoxin levels.
• Live attenuated vaccines (e.g., measles, mumps, rubella) may not work as well during and shortly after azithromycin treatment.
• Caution is advised when using Azithromycin with statins, as it may increase the risk of muscle-related side effects.

Following are the food interactions for Azithromycin 200mg/5ml Syrup/Suspension:

• Azithromycin can be taken with or without food, but taking it with food may reduce the risk of gastrointestinal side effects like nausea.
• Avoid consuming grapefruit and grapefruit juice as they can interfere with the metabolism of Azithromycin, leading to increased drug levels in the body.
• Alcohol consumption should be avoided as it may increase the risk of liver-related side effects and potential stomach issues.
• Dairy products like milk, cheese, and yogurt may reduce the absorption of Azithromycin, so it is best to take the medication 2 hours before or after consuming dairy.
• Caffeinated beverages may slightly decrease the absorption of Azithromycin, so it is advisable to limit coffee, tea, or energy drinks around the time of medication intake.
• Avoid high-fat meals as they can delay the absorption of Azithromycin, potentially affecting its effectiveness.
• Some fruit juices, especially apple and orange juice, may reduce the absorption of Azithromycin, so it is recommended to take the medication with water instead.
• Consult your healthcare provider for specific dietary instructions, especially if you have any underlying health conditions or are taking other medications.

Azithromycin 200mg/5ml Syrup/Suspension should be stored with care to maintain its effectiveness and safety. Keep the medication in a cool, dry place, ideally at room temperature, ensuring it is protected from direct sunlight and moisture. Always keep the bottle tightly sealed to prevent contamination. Avoid storing it in hot or humid environments like bathrooms or near heat sources, as temperature fluctuations can impact the medicine's quality. Pay attention to the expiration date, and properly dispose of any unused or expired syrup by following local guidelines or consulting your pharmacist. Do not dispose of it in sinks or toilets; instead, seek advice on appropriate disposal methods. Keep the medication securely stored away from children to prevent accidental consumption.

Following are the quick tips for Azithromycin 200mg/5ml Syrup/Suspension:

• Always follow the prescription guidelines provided by your healthcare professional for the best outcomes.
• Administer the correct dose using the measuring device provided to ensure accuracy.
• Ensure you complete the full course of medication, even if you feel better before finishing.
• Store the syrup at room temperature, away from direct sunlight and moisture.
• Do not share your medication with others, even if their symptoms seem similar.
• Inform your doctor about any other medications you are taking to prevent potential interactions.
• Contact your healthcare provider if you experience any persistent or severe side effects during treatment.

When taking Azithromycin, the lab tests that are required depend on a variety of factors, including the age of the patient, their health history, and the severity of the infection being treated. These tests are implemented to ensure that the vital signs and overall health of the patient are properly monitored during the course of the antibiotic treatment. Monitoring vital signs and overall health may include regular blood cell count checks, kidney function tests, and liver function tests to ensure that the medication is not causing any adverse effects on these vital organs. In addition, if any symptoms of an allergic reaction occur, such as a rash, hives, itching, or swelling of the lips, face, or throat, it is imperative to seek medical attention immediately. Due to the potential for severe allergic reactions, further lab tests may be required to rule out the possibility of an allergic reaction. Ultimately, it's important to note that the lab tests required while taking Azithromycin may differ from person to person and will likely be tailored to each individual by a medical professional based on their specific needs and factors.