Zezot (500mg) 6 Tablets

Zezot (500mg) 6 Tablets

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  • Manufacturer Bosch Pharmaceuticals (Pvt.) Ltd.
  • Generic Name Azithromycin

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Description

    Azithromycin is a valuable antibiotic that targets bacterial infections by interfering with their protein synthesis. It is effective against various bacteria, including Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus, and Moraxella catarrhalis. When introduced into the body, Azithromycin concentrates in the vacuoles of bacteria, specifically targeting the translocation step of peptide synthesis. It achieves this by binding to the 50S ribosomal subunits of the bacterial cell, thereby preventing the incorporation of amino acids into the growing polypeptide chain, ultimately resulting in bacterial cell death. Azithromycin is classified as a second-generation macrolide antibiotic, offering improved efficacy and pharmacokinetic properties compared to earlier generations. This includes a longer half-life and enhanced tissue distribution, allowing for less frequent dosing and a broader spectrum of activity against specific bacteria. In summary, Azithromycin's mechanism of action revolves around its ability to interfere with the fundamental process of bacterial protein synthesis, making it a crucial weapon in the treatment of various bacterial infections.

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  • Ingredients

    Azithromycin
  • Drug Class

    Macrolid

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  • Dosage Form

    Tablet

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  • Uses

    Unveiling its multifaceted uses and transformative applications as follows:

    • Treats a wide range of bacterial infections.
    • Effective for treating bronchitis, pneumonia, sinusitis, and skin infections.
    • Useful for preventing bacterial infections in individuals who are at an elevated risk of developing these infections.
    • Useful for treating cystic fibrosis.
    • Helps combat the growth of bacteria by inhibiting protein synthesis.

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  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Common Cold- 500mg once a day for 3 days
    • Flu- 500mg once a day for 3 days
    • Ear infections- 500mg once a day for 3 days
    • Strep Throat- 500mg once a day for 3 days
    • Bronchitis- 500mg once a day for 5 days
    • Pneumonia- 500mg once a day for 5 days
    • Skin infections- 500mg once a day for 3 days

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  • In case of Overdose

    Azithromycin is a medication that is used to treat a number of bacterial infections, and its overdose may lead to gastrointestinal problems such as nausea, vomiting, and diarrhea. More serious side effects may include liver inflammation and severe skin reactions. It is important to notify your doctor immediately if you believe you have taken an overdose of this medication. In treating an overdose, healthcare providers may induce vomiting or administer charcoal to neutralize the effects of the drug. Additional treatments may be required depending on the severity and symptoms of the overdose. Multiple medications, such as antacids, anxiolytics, and fluids, may be needed to aid recovery.

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  • Missed Dose

    When taking Azithromycin 250mg, it is important to adhere to the recommended dosage schedule, but if a dose is missed, the following steps should be taken:

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  • How To Use

    Before starting your course of Azithromycin, be sure to read the instructions that your healthcare provider gave you. Also, follow these steps for taking Azithromycin 250mg:

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  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • Anyone who has had an allergic reaction to Azithromycin or any other macrolide antibiotic in the past should avoid taking it.
    • Individuals with severe kidney disease or kidney failure should not take this medication.
    • Azithromycin should be used during pregnancy only if clearly necessary and the potential benefit justifies the potential risk to the fetus.
    • Since Azithromycin can pass into breast milk, it is recommended to consult with a healthcare provider before taking it if you are breastfeeding.

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  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Rash
    • Irritation of the mouth area, including tongue, lips, and cheeks
    • Mood changes or depression
    • Agitation
    • Nausea
    • Vomiting
    • Diarrhea
    • Constipation
    • Headache
    • Vertigo or dizziness
    • Tinnitus or ringing in the ears
    • Sore throat

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  • Precautions & Warnings

    The warnings and precautions associated with Azithromycin are:

    • Patients with history of hypersensitivity to azithromycin, erythromycin, or other macrolides.
    • Severe hepatic impairment.
    • QT prolongation or risk factors for cardiac arrhythmias (e.g., congenital or documented QT prolongation, uncorrected hypokalemia or hypomagnesemia).
    • Use with caution in patients with myasthenia gravis.
    • Renal impairment (GFR <10 ml/min).
    • Pregnancy and lactation.

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  • Drug Interactions

    The drug interactions with azithromycin include:

    • Antacids – Azithromycin absorption may be reduced if taken with antacids containing aluminum or magnesium.
    • Warfarin – May enhance the anticoagulant effect of warfarin, increasing the risk of bleeding.
    • Digoxin – Azithromycin may increase digoxin levels, leading to potential toxicity.
    • Cyclosporine – Azithromycin can increase cyclosporine levels, which may enhance the risk of adverse effects.
    • Statins (e.g., simvastatin) – Azithromycin may increase the risk of statin-related myopathy or rhabdomyolysis.
    • QT-Prolonging Drugs (e.g., certain antiarrhythmics) – Azithromycin may enhance the QT-prolonging effects of other drugs, increasing the risk of torsades de pointes.
    • Ergot Alkaloids – Concomitant use may increase the risk of ergot toxicity.
    • HIV Protease Inhibitors (e.g., ritonavir) – Can increase azithromycin levels, leading to an increased risk of side effects.

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  • Food Interactions

    For Azithromycin, food interactions that should be considered are:

    • Taking with food may help reduce gastrointestinal side effects.

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  • Storage/Disposal

    Store at room temperature, away from light, moisture, and heat. Keep the tablets in their original packaging and out of reach of children and pets. Do not store in the bathroom. Do not flush down the toilet or pour into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed.

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