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Ziabex (50mg) 14 Tablets
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- Manufacturer Standpharm Pakistan (Pvt.) Ltd.
- Generic Name Vildagliptin
Healthwire Pharmacy Ratings & Reviews (1500+)
4.9/
5
Delivery by Today, 9:00 am - 12:00 pm
Product Information
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Description
Vildagliptin; Inhibits dipeptidyl peptidase-4 (DPP-4) this mechanism results in prevention of degradation of glucagon-like peptide-1 (GLP-1) and reduction of glycaemia in patients with type 2 diabetes mellitus, with low risk for hypoglycemia and no weight gain. This drug covalently binds to the catalytic site of DPP-4, resulting in prolonged enzyme inhibition. This increases intact GLP-1 levels, both in the fasting state and after taking a meal. Vildagliptin stimulates insulin secretion and inhibits glucagon secretion in a glucose-dependent manner. At hypoglycemic levels, the counterregulatory glucagon response is enhanced relative to baseline by vildagliptin. Vildagliptin also inhibits glucose production in the liver, by changes in islet hormone secretion, and improves insulin sensitivity. These effects result in improved glycaemia with low risk for hypoglycemia. Vildagliptin also suppresses the levels of postprandial triglyceride (Triglyceride)-rich lipoprotein after ingestion of a fat-rich meal and reduces fasting lipolysis(lipid breakdown), resulting in inhibition of fat absorption and decreased Triglyceride stores in non-fat tissues. -
Ingredients
Vildagliptin -
Dosage Form
Tablet -
Uses
Diabetes Type 2 -
Dosage
Dose must be taken according to the doctor’s advice only; doses given below are suggested as supportive literature for better understanding in some areas of requirements. Adult dose: Vildagliptin; The usual dose is 50mg twice daily when used as monotherapy, with metformin, or with a thiazolidinedione and 50mg once daily (in the morning) when used with a sulfonylurea drug. -
In case of Overdose
Vildagliptin; its overdose can cause trouble while breathing, irregular heartbeat, severe dizziness and fainting. Metformin overdose can cause hypotension. Consult your doctor in case of overdose. -
Missed Dose
In case you missed any dose, take the next dose as soon as you remember, but don't double your next dose to compensate for the missed one. -
How To Use
All patients are advised to continue their recommended diet with an adequate distribution of carbohydrate intake during the day. -
When Not to Use
Vildagliptin should not be used in patients with type 1 diabetes, diabetic ketoacidosis, severe liver impairment, during pregnancy and breastfeeding (in extreme need, administration during pregnancy will be decided by the doctor). -
Side Effects
Nausea Constipation Headache Tiredness Swelling of face, lips and eyelids Excessive sweating -
Precautions & Warnings
Caution is required with the use of this medicine in kidney patients. -
Food Interactions
Balanced diet is necessary along with the use of this medicine, management of carbohydrate level in food is required. -
Storage/Disposal
Store at 25°C. Protect from heat and moisture.
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