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Zohydro (1/1%) 10g Cream
- Manufacturer Tabros Pharma (Pvt.) Ltd.
- Generic Name Clotrimazole
Healthwire Pharmacy Ratings & Reviews (1500+)
Product Information
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Description
Clotrimazole is an antifungal medication that functions through a multi-step mechanism of action. First, it penetrates fungal cell membranes. It then inhibits the synthesis of ergosterol, a crucial component of the fungal cell membrane. This disruption compromises the integrity of the membrane, leading to increased permeability and leakage of cellular contents. Ultimately, this inhibits fungal growth and replication. Clotrimazole is particularly effective against a wide range of fungal infections, including Candida species and dermatophytes.
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Ingredients
Clotrimazole -
Drug Class
Antifungal
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Dosage Form
Cream -
Uses
This cream is indicated in Fungal and gram-positive bacterial infections of the skin and nails. Fungal otitis externa. Vulvitis; balanitis; treatment of partner to prevent re-infection -
Dosage
Clotrimazole dosage for the indication of fungal skin infections, with a duration of 2-4 weeks or as advised:
- Adults and Children - Apply a thin layer to the affected area twice daily for 2-4 weeks.
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In case of Overdose
Overdose may lead to gastrointestinal distress. Seek medical help if symptoms persist.
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Missed Dose
If you miss a dose, consume as soon as you remember. If it is close to the next feeding, skip the missed dose. Do not double up on doses.
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How To Use
Applied topically to the affected area, usually once or twice daily. Follow the directions for application.
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When Not to Use
Clotrimazole should not be used if:
- Hypersensitivity
- Viral infections
- Pregnancy (during first trimester, topical use)
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Side Effects
Local mild burning, irritation. Hypersensitivity reactions, erythema or irritation -
Precautions & Warnings
Avoid contact with eyes -
Drug Interactions
The drug interactions with clotrimazole include:
- CYP3A4 Substrates (e.g., statins) – Can increase the levels of these drugs.
- Warfarin – Can enhance the effects of warfarin, increasing the risk of bleeding.
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Food Interactions
Clotrimazol has no documented food interactions that affect their efficacy or safety.
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Storage/Disposal
Clotrimazole should be stored at room temperature, away from light and moisture. It should be kept in its original packaging and out of reach of children. Dispose of any expired or unused Clotrimazole according to local disposal guidelines or use a drug take-back program.
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