Zolecta (250mg) 10 Capsules

Ciprofloxacin 250mg capsules primarily exert their antibacterial effect by inhibiting DNA gyrase, a type II topoisomerase enzyme essential for bacterial DNA replication, transcription, and repair. Ciprofloxacin binds to DNA gyrase, preventing it from unwinding and supercoiling DNA, which is necessary for various DNA-related processes in bacteria. This interference leads to the disruption of DNA synthesis and ultimately results in the death of susceptible bacterial cells. Specifically, Ciprofloxacin targets the A subunit of DNA gyrase, causing the accumulation of double-stranded DNA breaks and inhibiting DNA replication, thereby exerting its bactericidal effect. This mechanism of action is highly effective against a broad spectrum of Gram-positive and Gram-negative bacteria, making Ciprofloxacin a valuable antibiotic for treating various bacterial infections.

Ciprofloxacin 250mg

Fluoroquinolone antibiotic.

Capsule

The following are the uses of Ciprofloxacin 250mg Capsule:

• Used for treating bacterial infections such as pneumonia, bronchitis, and urinary tract infections.
• Used for controlling bacterial growth in severe bone and joint infections.
• Used to combat certain types of bacterial diarrhea and typhoid fever.
• Used for the treatment of bacterial skin infections and wound infections.
• Used for respiratory infections like sinusitis and chronic obstructive pulmonary disease (COPD) exacerbations.
• Used to manage certain eye and ear infections caused by bacteria.
• Used as a preventative measure for individuals with a compromised immune system to reduce the risk of bacterial infections.

In the case of an overdose of Ciprofloxacin 250mg Capsules, individuals may experience a range of adverse effects. These can include gastrointestinal symptoms such as nausea, vomiting, and diarrhea, as well as more severe reactions like seizures, dizziness, and changes in heart rate or rhythm. It is important to recognize that an overdose may lead to serious health complications, particularly if a large quantity is ingested. Prompt medical intervention is necessary to manage the symptoms and prevent potential long-term damage to the body.

In the case of a missed dose of Ciprofloxacin 250mg Capsule, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one. Never double the dose to make up for a missed one, as this may increase the risk of side effects. It is generally recommended to maintain a consistent dosing schedule, but if you frequently miss doses, consult your healthcare provider for advice on how to adjust your medication routine. They will guide you on the best course of action to ensure the medication's effectiveness.

To take Ciprofloxacin 250mg Capsule, swallow the capsule whole with a full glass of water, ensuring you complete the full course as prescribed by your healthcare provider, typically taken every 12 hours for the duration specified.

Following are the conditions/situations when Ciprofloxacin 250mg Capsule should not be taken:

• Do not take if you have a known allergy to Ciprofloxacin or any other quinolone antibiotics.
• Avoid if you have a history of myasthenia gravis, as it can worsen muscle weakness.
• Not suitable for individuals with a history of tendon disorders or tendon rupture.
• Contraindicated in patients with epilepsy or other seizure disorders, as it may lower the seizure threshold.
• Should not be used in patients with central nervous system disorders (CNS) or an increased risk of seizures.
• Avoid if you have a history of heart rhythm problems, especially QT prolongation.
• Do not take if you have severe kidney disease without adjusting the dose.
• Contraindicated in children and adolescents under 18 years old, as it can affect bone and joint development.
• Not recommended for pregnant women due to potential risks to the fetus.
• Avoid if you have a history of liver disease or if your liver function tests are abnormal.

The side effects of Ciprofloxacin 250mg Capsule may include:

• Nausea and vomiting
• Diarrhea
• Dizziness
• Headache
• Confusion or disorientation
• Skin rash or itching
• Increased sensitivity to sunlight
• Joint or muscle pain

Following are the precautions and warnings for Ciprofloxacin 250mg Capsule:

• Do not take if you are allergic to Ciprofloxacin or any other quinolone antibiotics.
• This medication may cause tendon damage, especially in those over 60 years old, athletes, and those taking corticosteroids; report any tendon pain or swelling immediately.
• Ciprofloxacin can increase sensitivity to sunlight; avoid prolonged sun exposure and tanning beds.
• It may cause dizziness or lightheadedness, so avoid driving or operating machinery until you know how it affects you.
• Inform your doctor if you have a history of kidney, liver, or heart disease as dose adjustments may be necessary.
• Pregnant and breastfeeding women should consult their doctor before taking this medication, as it may harm the unborn baby or infant.
• Avoid taking Ciprofloxacin with dairy products, antacids, or mineral supplements as they can interfere with absorption.

Following are the drug interactions for Ciprofloxacin 250mg Capsule:

• Avoid concurrent use with tizanidine due to increased risk of serious adverse events, including cardiac arrhythmias.
• Theophylline levels can be elevated, increasing the risk of theophylline-related side effects.
• May reduce the effectiveness of oral contraceptives, leading to breakthrough bleeding and potential contraceptive failure.
• Probenecid can decrease the elimination of Ciprofloxacin, resulting in increased Ciprofloxacin levels and potential toxicity.
• Antacids containing magnesium or aluminum may decrease the absorption of Ciprofloxacin, reducing its effectiveness.
• The risk of central nervous system (CNS) stimulation and seizures may increase when combined with certain medications like bupropion.
• Ciprofloxacin may enhance the effects of warfarin and other anticoagulants, necessitating close monitoring for bleeding.

Following are the food interactions to be aware of with Ciprofloxacin 250mg Capsules:

• Avoid consuming dairy products like milk, yogurt, or cheese with Ciprofloxacin. Calcium can interfere with the absorption of the medication, reducing its effectiveness.
• Limit caffeine intake from coffee, tea, or energy drinks as it can increase the side effects of Ciprofloxacin, causing increased heart rate and nervousness.
• Grapefruit and grapefruit juice should be avoided as they can affect the metabolism of Ciprofloxacin, leading to increased drug levels in the body and potential toxicity.
• Avoid alcohol consumption as it can enhance the adverse effects of Ciprofloxacin, particularly on the central nervous system, and may increase the risk of liver-related side effects.
• Iron-rich foods like red meat, spinach, and beans should be separated from Ciprofloxacin doses by at least 2 hours to prevent decreased absorption of the medication.
• Antacids containing magnesium or aluminum can reduce the absorption of Ciprofloxacin. Avoid taking them together; a gap of at least 4 hours is recommended.
• Consuming high-fat meals can slow the absorption of Ciprofloxacin, potentially delaying its therapeutic effect. It is best to take the medication on an empty stomach.
• Always follow healthcare provider's advice on specific dietary restrictions or recommendations while taking Ciprofloxacin.

Ciprofloxacin 250mg Capsules should be stored in a dry and cool environment, ideally at room temperature, ensuring protection from direct sunlight and moisture. Keep the medication securely sealed in its original container to maintain its integrity and prevent contamination. It is crucial to avoid exposing the capsules to extreme temperatures, so steer clear of storage areas like bathrooms or near heat-emitting appliances. Always exercise caution by checking the expiration date before use, and when disposing of unused or expired capsules, refrain from flushing them or pouring them down the drain. Instead, seek guidance from a pharmacist or healthcare professional for safe disposal practices. Additionally, ensure that the medication is stored out of children's reach to prevent accidental consumption.

Following are the quick tips for Ciprofloxacin 250mg Capsule:

• Take the capsule with a full glass of water for better absorption.
• Consume the capsule at the same time each day to maintain consistent medication levels.
• Swallow the capsule whole; do not crush, chew, or break it.
• Avoid taking with dairy products, calcium-rich foods, or iron supplements as they may interfere with absorption.
• Store the capsules at room temperature, away from moisture and direct sunlight.
• Do not skip doses; complete the full prescribed course even if you feel better.
• Inform your doctor if you have any allergies or medical conditions before taking this medication.