Zomig (2.5mg) 3 Tablets

Zomig (2.5mg) 3 Tablets

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  • Manufacturer ICI Pakistan
  • Generic Name Zolmitriptan

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Laboratory Screening
  • Description

    Zolmitriptan, a selective serotonin receptor agonist, acts by binding to specific serotonin receptors, primarily the 5-HT1B and 5-HT1D receptors, located in cranial blood vessels and the trigeminal system. Upon binding, it induces vasoconstriction of these blood vessels, reduces inflammation, and inhibits the transmission of pain signals in the trigeminal pathway. This mechanism is believed to alleviate the symptoms of migraine by reducing the dilatation of cerebral blood vessels and decreasing the release of vasoactive peptides, thus reducing the pain and associated symptoms of migraine attacks.

  • Ingredients

    Zolmitriptan
  • Drug Class

    Triptan

  • Dosage Form

    Tablet

  • Uses

    The following are the uses of Zolmitriptan 5mg Tablet:

    • Used for treating migraine attacks.
    • Effective in relieving migraine-related symptoms such as headaches, nausea, and sensitivity to light and sound.
    • Helps stop a migraine attack and prevent its recurrence.
    • Can be taken at the onset of a migraine to provide faster relief.
    • May be used as a standalone treatment or in combination with other migraine medications.
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • For adults the recommended dosage is 81 mg per day for common cold and 8 • 11 mg per day for general adult consumption.
    • For children up to the age of 11 years the recommended dosage is 14 mg per day for common cold.
    • For patients with eye disease, the recommended dose is 65 mg elemental Zinc a day.
  • In case of Overdose

    In the case of an overdose of Zolmitriptan 5mg Tablets, the primary concern is the potential for an increase in adverse effects. Symptoms may include severe chest pain, tightness, or pressure, and individuals may experience heightened sensitivity to touch and sound. Nausea, vomiting, and dizziness can also occur. Promptly seek medical advice if you suspect an overdose, as treatment options should be discussed with a healthcare professional to manage the symptoms effectively and ensure a safe recovery.

  • Missed Dose

    In the case of a missed dose of Zolmitriptan 5mg Tablet, it is recommended to take the medication as soon as you remember, but there are a few important considerations. If you are close to the time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. It's important to maintain a consistent dosing routine for optimal effectiveness.

  • How To Use

    To take Zolmitriptan 5mg Tablets, place the tablet under your tongue and allow it to dissolve completely without chewing or swallowing, following the prescribed dosage instructions provided by your healthcare professional.

  • When Not to Use

    Following are the conditions when Zolmitriptan 5mg Tablet should not be used:

    • Should not be taken by individuals with a known allergy or hypersensitivity to Zolmitriptan or other triptans.
    • Contraindicated in patients with a history of cardiovascular disease, including heart attack, stroke, or uncontrolled high blood pressure.
    • Not suitable for individuals with severe liver or kidney impairment.
    • Should not be used by patients with hemiplegic or basilar migraine.
    • Contraindicated in patients with uncontrolled epilepsy or certain types of migraine aura.
    • Should not be taken within 24 hours of using other migraine medications, such as ergotamine or other triptans.
    • Not recommended for individuals with risk factors for cardiovascular disease, including diabetes, high cholesterol, obesity, or smoking.
    • Do not use if you have peripheral vascular disease or ischemic bowel disease.
    • Contraindicated in patients with uncontrolled hypertension.
  • Side Effects

    The side effects of Zolmitriptan 5mg Tablet may include:

    • Dizziness
    • Fatigue
    • Sensations of tingling, prickling, or numbness
    • Dry mouth
    • Neck stiffness
    • Nausea
    • Chest tightness or discomfort
    • Increased heart rate
  • Precautions & Warnings

    Following are the precautions and warnings for Zolmitriptan 5mg Tablet:

    • Not recommended for individuals with a history of allergic reactions to Zolmitriptan or related compounds.
    • Patients with cardiovascular disease, hypertension, or risk factors for coronary artery disease should exercise caution and consult a healthcare professional before use.
    • This medication may cause dizziness or drowsiness; patients should avoid driving or operating machinery until they know how the medication affects them.
    • Not recommended for use in pregnant or breastfeeding women unless the potential benefits outweigh the risks.
    • Should not be used in patients with uncontrolled hypertension as it may increase blood pressure.
    • Patients with liver or kidney impairment may require dose adjustments, and regular monitoring is advised.
    • Zolmitriptan should not be used within 24 hours of taking ergotamine-containing medications or other serotonin agonists.
  • Drug Interactions

    Following are the drug interactions for Zolmitriptan 5mg Tablet:

    • Other triptans or ergotamine-containing medications can lead to prolonged and increased vasospastic reactions, and should not be taken within 24 hours of each other.
    • Selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) may increase the risk of serotonin syndrome when used with Zolmitriptan.
    • The effectiveness of Zolmitriptan may be reduced when used with strong CYP1A2 inhibitors like fluvoxamine.
    • Concomitant use of Zolmitriptan with moderate CYP1A2 inhibitors such as ciprofloxacin or fluconazole should be done with caution.
    • Avoid using monoamine oxidase inhibitors (MAOIs) within 14 days of taking Zolmitriptan, as it may lead to potentially fatal reactions.
    • The risk of coronary artery vasospasm may increase when Zolmitriptan is used with selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs).
    • Certain antidepressants, such as tricyclic antidepressants and St. John's Wort, may increase the effects of Zolmitriptan and should be used with caution.
  • Food Interactions

    Following are the food interactions for Zolmitriptan 5mg Tablet:

    • Avoid consuming large amounts of caffeine while taking this medication, as it can increase the risk of side effects such as increased heart rate and blood pressure.
    • Grapefruit and grapefruit juice should be consumed in moderation as they may affect the metabolism of Zolmitriptan, potentially leading to higher drug levels in the body.
    • Alcohol should be limited or avoided during treatment, as it can increase the risk of side effects such as dizziness, drowsiness, and may also affect the effectiveness of the medication.
    • Avoid foods rich in tyramine (aged cheeses, cured meats, fermented foods) as they can potentially interact with Zolmitriptan and increase blood pressure.
    • Chocolate and cocoa products contain compounds that can affect blood vessels and may interact with Zolmitriptan's action.
    • Spicy foods are not recommended immediately after taking the tablet to prevent potential stomach irritation.
    • It is generally advised to maintain a consistent diet and avoid significant changes during the course of treatment.
    • Always consult your healthcare provider for personalized advice regarding dietary restrictions and interactions with Zolmitriptan.
  • Storage/Disposal

    Zolmitriptan 5mg Tablets should be stored in a secure and dry location, away from direct sunlight, moisture, and extreme temperatures. The original packaging should be retained, ensuring the medication remains sealed and protected from environmental factors. It is crucial to keep the tablets out of the reach of children and pets to prevent accidental consumption. Regularly check the expiration date, and dispose of any unused or expired tablets promptly. Proper disposal methods should be followed, avoiding flushing or pouring them down the drain. Consult your pharmacist or local waste disposal company for guidance on appropriate disposal practices to ensure environmental safety. Never discard Zolmitriptan tablets with regular household waste or recycle them without proper guidance.

  • Quick Tips, if any

    Following are the quick tips for Zolmitriptan 5mg Tablet:

    • Take the tablet as soon as possible after the onset of a migraine attack as directed by your doctor.
    • Ensure you swallow the tablet whole with a full glass of water, do not crush or chew it.
    • Zolmitriptan can be taken with or without food, but taking it with food may reduce the risk of side effects.
    • Avoid driving or operating heavy machinery until you know how this medication affects you, as it may cause dizziness.
    • Do not take more than the prescribed dose; excessive use may lead to increased side effects.
    • Inform your doctor if you have a history of heart disease, as Zolmitriptan may not be suitable for you.
    • Store the tablets at room temperature, away from moisture and direct sunlight.
  • Laboratory Screening

    Before taking Zolmitriptan 2.5mg, it is crucial to disclose your medical history and any known allergies to your healthcare provider to ensure the safest and most effective use of the medication. Your doctor may perform specific laboratory tests, including:

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