ZOPICLONE TAB 7.5MG 28 S

Zopiclone 5MG Tablet primarily acts as a positive allosteric modulator of the gamma-aminobutyric acid (GABA) type A receptors in the central nervous system. By binding to these receptors, it enhances the inhibitory effects of GABA, a neurotransmitter that reduces neuronal excitability. This modulation increases the frequency of chloride channel opening, allowing more chloride ions to enter the neurons, which stabilizes the neuronal membrane, leading to a decrease in neuronal activity and an overall sedative and anxiolytic effect. This mechanism helps in promoting sleep and is particularly useful in treating insomnia by improving sleep initiation and sleep maintenance.

Zopiclone 5MG Tablet is a non-benzodiazepine hypnotic.

Tablet

The following are the uses of Zopiclone 5MG Tablet:

• Used for treating insomnia and improving sleep patterns.
• Used for resetting the sleep-wake cycle, helping individuals fall asleep faster.
• Used to enhance sleep quality, ensuring a more restful and uninterrupted sleep.
• Used for managing sleep disturbances, allowing users to stay asleep for longer periods.
• Used in the short-term treatment of insomnia, typically prescribed for a limited duration.
• Used to alleviate symptoms of insomnia such as frequent awakenings and early morning awakenings.
• Used to improve overall sleep efficiency, ensuring users feel more refreshed upon waking.

In the case of an overdose of Zopiclone 5MG Tablets, several symptoms may occur, including extreme drowsiness, confusion, and difficulty in staying awake. Physical symptoms might include slow and shallow breathing, and individuals may experience coordination problems and impaired balance. It is essential to seek medical assistance immediately if an overdose is suspected, as prompt treatment can help mitigate these effects and prevent potential complications. The medical team can provide the necessary support and care to address the overdose effectively.

To take Zopiclone 5MG Tablet, swallow the tablet whole with a glass of water, preferably before bedtime, following the dosage instructions provided by your healthcare professional, ensuring a full 7-8 hours of uninterrupted sleep after ingestion.

Here are the conditions and situations when Zopiclone 5mg Tablet should not be used:

• Should not be taken by individuals who are allergic to zopiclone or any other similar medications (hypnotics or benzodiazepines).
• Contraindicated in patients with severe respiratory problems or sleep apnea.
• Not suitable for individuals with severe liver or kidney impairment.
• Should be avoided if you have a history of substance abuse or dependence.
• Not recommended for children or adolescents under 18 years of age.
• Do not use if you have myasthenia gravis, severe liver failure, or respiratory failure.
• Contraindicated in individuals with severe depression or suicidal thoughts.
• Avoid using if you have a pre-existing condition that affects your breathing or lung function.
• Do not take Zopiclone if you are pregnant or breastfeeding, as it can cause harm to the baby.
• Should not be used for long-term treatment of insomnia without consulting a doctor.

The side effects of Zopiclone 5MG Tablet may include:

• Drowsiness or sleepiness during the day
• Dizziness or lightheadedness
• Taste changes or a bitter aftertaste
• Dry mouth
• Headache
• Fatigue or weakness
• Memory impairment or forgetfulness
• Confusion or difficulty concentrating

Following are the precautions and warnings:

• Zopiclone 5MG Tablet should not be used in individuals with a known hypersensitivity or allergy to zopiclone or any other ingredients in the tablet.
• This medication is intended for short-term use only, typically up to 4 weeks. Prolonged use without medical supervision can lead to dependence and withdrawal symptoms.
• Patients with a history of substance abuse or addiction should exercise caution as zopiclone has the potential for misuse and may be habit-forming.
• It may cause drowsiness and impair your ability to drive or operate machinery. Avoid these activities until you know how the medication affects you.
• Zopiclone can affect cognitive and psychomotor performance, so caution is advised in situations where full alertness is required.
• Elderly patients may be more sensitive to the effects of zopiclone, and dosage adjustments might be necessary.
• Consult a healthcare professional before use if you have a history of liver, kidney, or respiratory problems, as zopiclone metabolism and excretion can be affected by these conditions.
• Pregnant and breastfeeding women should only use Zopiclone 5MG Tablet after consulting a healthcare provider, as the risks and benefits need to be carefully weighed.

Following are the drug interactions for Zopiclone 5MG Tablet:

• Alcohol and other central nervous system (CNS) depressants, like opioids or benzodiazepines, can increase sedation and respiratory depression, leading to potential serious adverse effects.
• Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole) can significantly increase zopiclone concentrations, enhancing its effects and side effects.
• CYP3A4 inducers (e.g., rifampicin, St. John's Wort) may decrease zopiclone levels, reducing its effectiveness.
• Antidepressants such as SSRIs and tricyclic antidepressants may increase the sedative effects of zopiclone.
• Zopiclone may increase the risk of side effects when taken with other medications that cause dizziness, such as antihistamines.
• It can interact with anticonvulsants, possibly reducing seizure threshold.
• Concomitant use with other sleep medications is not recommended due to additive CNS depression.

Following are the food interactions to be aware of when taking Zopiclone 5MG Tablet:

• Grapefruit and grapefruit juice consumption should be avoided as they can influence the metabolism of Zopiclone, potentially increasing its levels in the blood and leading to enhanced side effects.
• Alcohol should be strictly avoided as it can potentiate the sedative effects of Zopiclone, causing excessive drowsiness and impairing cognitive functions.
• Heavy meals, especially high-fat diets, may delay the absorption of Zopiclone, affecting its onset of action. It is best to take the medication on an empty stomach.
• Caffeine-rich beverages like coffee and energy drinks should be limited as they can counteract the sedative effects of Zopiclone, making it less effective.
• Dairy products, particularly milk, may interact with Zopiclone, reducing its absorption. It is advisable to separate milk intake from medication timing.
• Spicy foods might irritate the stomach lining and exacerbate gastrointestinal side effects associated with Zopiclone.
• Avoid consuming herbal teas or supplements containing St. John's Wort, as it can decrease Zopiclone's effectiveness.
• Always follow the advice of your healthcare provider regarding specific dietary instructions while using this medication.

Zopiclone 5MG Tablets should be stored in a secure and dry location, preferably in a medicine cabinet or a designated storage area, away from moisture, heat, and direct sunlight. Keep the tablets in their original packaging, ensuring the container is tightly sealed to maintain their integrity. It is crucial to store the medication at room temperature, avoiding extreme temperatures to prevent degradation. Always check the expiration date before use, and never use the tablets if they appear damaged or discolored. When disposing of unused or expired tablets, do not flush them or throw them into the trash. Instead, follow local guidelines for medication disposal or consult a pharmacist for safe disposal options to protect the environment and prevent misuse. Keep the medication out of children's reach to ensure their safety.

Following are the quick tips for Zopiclone 5MG Tablet:

• Take the tablet just before bedtime as directed by your doctor.
• Swallow the tablet whole with a glass of water, do not crush or chew.
• Avoid taking with or soon after a heavy meal to ensure optimal absorption.
• Do not drive or operate machinery after taking this medication as it may cause drowsiness.
• Inform your doctor if you have a history of liver, kidney, or respiratory problems.
• Store the tablets in a cool, dry place away from direct sunlight.
• Do not share this medication with others; it is prescribed specifically for your condition.