Good Cholesterol Recedes Chances of Alzheimer’s Disease


by Hamna Bano

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According to a recent study in the Journal of the Alzheimer’s Association, it has been revealed that Good Cholesterol or high-density lipoprotein (HDL) at high levels can decrease the risk of Alzheimer’s disease.

Alzheimer’s disease is a disorder that has impacted a huge number of people and has influenced their ability to function normally in everyday life. Researchers however are still developing an understanding of the condition.

The study conducted included 180 participants 60 years of age. The participants were from the University of Southern California Alzheimer’s Disease Research Center (ADRC). The deduction was made after noticing the cognitive functions through a lot of cognitive tests.

On observation of the levels of small HDL in the CSF, it was found that higher levels of small HDL particles were associated with improved cognitive function among those who participated.


The results of this study are still expected to lead to the development of new therapies for Alzheimer’s disease.

Study author Hussein Yassine said that “The discovery of lipid particles (LDL, HDL) in [the] blood will lead to several advances in drug discovery for cardiovascular disease treatment and prevention. Here for the first time, we measure HDL particles in cerebrospinal fluid as a surrogate of brain HDL and find that greater levels of small HDL correlate with better performance on cognitive measures.”

He further added that “Now that we have this biomarker, our next step is to figure out what promotes the formation of these small HDL particles in the brain. Such new discoveries could then lead to a new list of medications in our fight against Alzheimer’s.”

The Alzheimer’s Association is optimistic about the results of the study and is expecting further experimentation to be done in the future.