Overview of Acrodermatitis

Acrodermatitis is also known as Gianotti Crosti Syndrome. It is a very commonly occurring disease in children and is visible by spots or blisters on the body.

Signs and Symptoms of Acrodermatitis

Children have been affected by numerous diseases over the years and will continue to do so. It is because their immune systems are still developing and sometimes genetics play a role as well. Acrodermatitis is one of the many common skin conditions that affect children.

The full name of Acrodermatitis is “Papular Acrodermatitis of Childhood”. The name itself indicates that it primarily affects children, mainly from ages 3 months to 15 years. It is also known as Papular Acrodermatitis, Gianotti Crosti Syndrome (GCS), or Infantile Acrodermatitis.

It causes red or purple, itchy blisters. Since red blisters are an indication of many infections, a thorough check-up is required for the diagnosis of the disease.

If a sibling of a child has had interaction with the disease, chances for the child himself to develop the disease are also high. Children can still carry the disease even after being cleared of all symptoms.

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Types of Acrodermatitis

Symptoms of this syndrome develop over three to four days. Some of the common symptoms are below:

  • Asymmetrical spots (5-10mm in diameter)
  • Red spots or patches on arms, legs, and buttocks
  • Non-itchy spots in the beginning
  • Swelling and tenderness in the abdomen and lymph nodes
  • Flat patches, firm to the touch
  • Purple spots at a later stage
  • Mild temperature
  • No rash on the back, chest, or belly area

Risk Factors of Acrodermatitis
  • The exact cause of this disorder is unknown but it is linked with many other infections.
  • It is mainly linked with a viral infection. The virus itself is contagious and can be contracted by other children.
  • In America, the Epstein-Barr virus (EBV) is associated with acrodermatitis while in Italy; the Hepatitis B virus is associated with acrodermatitis. In Pakistan, EBV is the main virus connected with this syndrome.

Usually, vaccines work against bacteria or viruses that attack our bodies. In very rare cases the opposite happens. In this scenario, vaccines lead to the development of acrodermatitis, such as;

  • Smallpox
  • Chickenpox
  • Diphtheria
  • Influenza
  • Poliovirus



Many other infections can also cause acrodermatitis. Some of the other viruses associated with this disorder are as follows:

  • Parainfluenza virus
  • Respiratory syncytial virus (RSV)
  • Coxsackievirus
  • Cytomegalovirus
  • Echovirus
  • Enterovirus
  • Rotavirus
  • Hepatitis A, B, C
  • HIV


Acrodermatitis is a medical condition that is caused by viral infections. The best preventive means to lower the risk of acquiring this disease is by avoiding any viral infection. You should make sure that your child is taking care of his or her personal hygiene.

  • Make sure their hands are clean and properly sanitized
  • They are wearing neat and clean cloths
  • Tell them to maintain a safe distance from anyone who is sick

Treatment of Acrodermatitis | When to Consult a Doctor

Since it is similar to many other rashes, just symptoms are not enough for a proper diagnosis. Tests are performed to rule out other infections and diseases and to confirm this disorder:

  • Blood Count
  • Liver Function Test (liver enzymes)
  • Viral Serology or PCR
  • Bilirubin Level
  • Screening of EBV antibodies
  • Skin biopsy

Doctors to treat Acrodermatitis

Last updated on Wednesday 23/11/2022


Dr. Asif Rauf

Cosmetologist, Dermatologist | MBBS

Cosmolux ( The Hair & Skin Clinic )Rs 2000


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Highly Recommended


Dr. Farrukh Aslam

Cosmetologist | MBBS, FCPS, BFIRST Fellow, MRCPS, FACS

LaForma ClinicRs 1500


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Dr farukh is a kind man he listen whatever i said and then he diagnosed me the treatment of my issue


Dr. Aamir Chhipa

Cosmetologist, Dermatologist | MBBS, DCDD

Dr Aamir Skin ClinicRs 1000


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I am very satisfied with the overall doctor's experience.

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